77 completed, 12 terminated, 4 unknown, 2 withdrawn. 96 Phase 2, 37 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 96 | Completed 77, Terminated 12, Unknown 4, Withdrawn 2, Recruiting 1 |
| Phase 1 | 37 | Completed 28, Terminated 4, Unknown 3, Recruiting 1, Withdrawn 1 |
| Phase 3 | 2 | Completed 2 |
Follow Unspecified Adult Solid Tumor, Protocol Specific: new trials by email Literature Review of Unspecified Adult Solid Tumor, Protocol Specific trials Research Report on Unspecified Adult Solid Tumor, Protocol Specific
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 1/2 Clinical Trial of CP-506 (HAP) in Monotherapy or With Carboplatin or ICI CP-506, Carboplatin, Immune checkpoint inhibitor - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 / Phase 2 | Recruiting | Maastricht University Medical Center | 126 | 2023-05-30 | 2025-10-07 |
| A Phase 1/2 Multicenter Dose Escalation and Expansion Study Of NKTR-214 In Subjects With Locally Advanced Or Metastatic Solid Tumors NKTR-214 - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 / Phase 2 | Completed | Nektar Therapeutics | 28 | 2015-12-01 | 2021-07-29 |
| Bevacizumab in Pats w/ Recurrent ST Brain Metas Who Have Failed Whole Brain Radiation Therapy bevacizumab, quality-of-life assessment - Metastatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific | Phase 2 | Completed | Northwestern University | 27 | 2013-11-27 | 2019-09-17 |
| 18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy 18F-fludeoxyglucose (18F-FDG), 18F-FPPRGD2 - Adult Giant Cell Glioblastoma, Adult Glioblastoma | Phase 1 / Phase 2 | Completed | Sanjiv Sam Gambhir | 25 | 2013-03-04 | 2019-10-03 |
| A Study of KX2-391 With Paclitaxel in Patients With Solid Tumors KX2-391 and Paclitaxel - Unspecified Adult Solid Tumor, Protocol Specific, Gastric Cancer | Phase 1 / Phase 2 | Unknown | Hanmi Pharmaceutical Company Limited | 60 | 2012-12-01 | 2015-05-18 |
| Probiotic Supplementation in Preventing Treatment-Related Diarrhea in Patients With Cancer Undergoing Chemotherapy Lactobacillus plantarum strain 299v, Lactobacillus acidophilus probiotic, placebo - Diarrhea, Unspecified Adult Solid Tumor, Protocol Specific | Phase 2 | Withdrawn | Stanford University | 2012-11-01 | 2014-02-14 | |
| A Dose Escalation Trial of PR610 Treating Patients With Solid Tumors PR610 - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 / Phase 2 | Terminated | Proacta, Incorporated | 33 | 2012-08-01 | 2014-06-16 |
| Avoiding the Hippocampus During Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases intensity-modulated radiation therapy - Cognitive/Functional Effects, Metastatic Cancer | Phase 2 | Completed | Radiation Therapy Oncology Group | 113 | 2011-03-01 | 2017-09-27 |
| Benazepril Hydrochloride, Lisinopril, Ramipril, or Losartan Potassium in Treating Hypertension in Patients With Solid Tumors lisinopril, losartan potassium, laboratory biomarker analysis - Hypertension, Unspecified Adult Solid Tumor, Protocol Specific | Phase 2 | Terminated | Wake Forest University Health Sciences | 6 | 2011-02-01 | 2018-08-28 |
| S0916, MLN1202 in Treating Patients With Bone Metastases anti-CCR2 monoclonal antibody MLN1202, polymorphism analysis, laboratory biomarker analysis - Metastatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific | Phase 2 | Completed | SWOG Cancer Research Network | 44 | 2010-03-01 | 2018-08-09 |
| Vaccine Therapy and 1-MT in Treating Patients With Metastatic Breast Cancer adenovirus-p53 transduced dendritic cell (DC) vaccine, 1-methyl-d-tryptophan, Laboratory biomarker analysis - Male Breast Cancer, Recurrent Breast Cancer | Phase 1 / Phase 2 | Completed | H. Lee Moffitt Cancer Center and Research Institute | 44 | 2009-12-28 | 2018-04-11 |
| Magnesium Oxide in Treating Hot Flashes in Menopausal Women With Cancer magnesium oxide, questionnaire administration, quality-of-life assessment - Breast Cancer, Cancer Survivor | Phase 2 | Completed | Virginia Commonwealth University | 31 | 2009-07-01 | 2016-06-21 |
| Electrical Stimulation Therapy Using the MC5-A Scrambler in Reducing Peripheral Neuropathy Caused by Chemotherapy questionnaire administration, Sensory Neuropathy Scale instrument, Quality of Life instrument - Chemotherapeutic Agent Toxicity, Neurotoxicity | Phase 2 | Completed | Virginia Commonwealth University | 18 | 2009-06-12 | 2017-03-29 |
| Cognitive Behavioral Therapy With or Without Armodafinil in Treating Cancer Survivors With Insomnia and Fatigue After Chemotherapy Quality-of-Life Assessment, Questionnaire Administration, Placebo - Unspecified Adult Solid Tumor, Protocol Specific | Phase 2 | Completed | Abramson Cancer Center at Penn Medicine | 226 | 2009-06-01 | 2020-04-09 |
| Sunitinib Malate After Stereotactic Radiosurgery in Treating Patients With Newly Diagnosed Brain Metastases sunitinib malate, cognitive assessment - Cognitive/Functional Effects, Metastatic Cancer | Phase 2 | Terminated | Case Comprehensive Cancer Center | 14 | 2009-04-01 | 2014-09-29 |
| Stereotactic Body Radiation Therapy and Vertebroplasty in Treating Patients With Localized Spinal Metastasis radiation - Metastatic Cancer, Pain | Phase 2 | Completed | University of Texas Southwestern Medical Center | 35 | 2009-02-01 | 2022-03-16 |
| Donor Natural Killer Cells After Donor Stem Cell Transplant in Treating Patients With Advanced Cancer donor natural killer cell infusion - Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders | Phase 1 / Phase 2 | Completed | Asan Medical Center | 47 | 2009-01-01 | 2013-02-20 |
| Sorafenib in Treating Patients With Advanced Malignant Solid Tumors Sorafenib - Unspecified Adult Solid Tumor, Protocol Specific | Phase 2 | Completed | University of California, Davis | 50 | 2008-12-01 | 2018-01-10 |
| Stereotactic Radiosurgery in Treating Patients With Brain Metastases therapeutic conventional surgery, stereotactic radiosurgery - Metastatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific | Phase 2 | Terminated | Duke University | 6 | 2008-10-01 | 2013-11-25 |
| Stereotactic Radiosurgery After Surgery in Treating Patients With Brain Metastases MMSE, QOL via FACT-Br, MRI - Metastatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific | Phase 2 | Terminated | Duke University | 1 | 2008-08-01 | 2019-02-26 |
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Carcinoma, Non-Small-Cell Lung (17) · Neoplasm Metastasis (17) · Lung Neoplasms (15) · Breast Neoplasms (14) · Burkitt Lymphoma (13) · Leukemia, Lymphocytic, Chronic, B-Cell (13) · Lymphoma (13) · Lymphoma, B-Cell, Marginal Zone (13) · Lymphoma, Follicular (13) · Lymphoma, Large B-Cell, Diffuse (13) · Lymphoma, Large-Cell, Immunoblastic (13) · Lymphoma, Mantle-Cell (13) · Lymphoma, Non-Hodgkin (13) · Hodgkin Disease (12) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (12)
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David R. Gandara, MD (3) · Robert O. Dillman, MD, FACP (3) · Charles L. Wiseman, MD, FACP (2) · Hamidreza Aliabadi, MD (2) · James E. Herndon, PhD (2) · Jamie Hayden Von Roenn, MD (2) · John H. Sampson, MD, PhD (2) · John P. Kirkpatrick, MD (2) · Philip L. McCarthy, MD (2) · Steven A. Rosenberg, MD, PhD (2) · Thomas J. Smith, MD (2) · Albert G. Hakaim, MD (1) · Alessandro Olivi, MD (1) · Allan Y. Chen, MD, PhD (1) · Angela Davies, MD (1)
PMID 10850352, PMID 12843799, PMID 12906958, PMID 14767498, PMID 15623609, PMID 17418968, PMID 17545536, PMID 18090584, PMID 18327587, PMID 19170225, PMID 19494788, PMID 21234281, PMID 21271347, PMID 21620511, PMID 22015991, PMID 22688670, PMID 24013936, PMID 25349290, PMID 25965900, PMID 26062933, PMID 26611425, PMID 29867922, PMID 30850872, PMID 30988166, PMID 31138725, PMID 36482188, PMID 37315579, PMID 39285365, PMID 41170811, PMID 41811823, PMID 8399072
P30CA093373 (3), P30CA015083 (2), P30CA033572 (2), P30CA043703 (2), P30CA051008 (2), U10CA031946 (2), 2016 (1), N01CM17107 (1), P30CA006516 (1), P30CA008748 (1), P30CA014236 (1), P30CA016059 (1), P30CA016087 (1), P30CA021765 (1), P30CA022453 (1)