607 completed, 74 terminated, 34 unknown, 30 withdrawn. 502 Phase 1, 96 Phase 2, 88 Not applicable, 67 Phase 3, 5 Early Phase 1.
Follow Unspecified Adult Solid Tumor, Protocol Specific: new trials by email Literature Review of Unspecified Adult Solid Tumor, Protocol Specific trials Research Report on Unspecified Adult Solid Tumor, Protocol Specific
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 1/2 Clinical Trial of CP-506 (HAP) in Monotherapy or With Carboplatin or ICI CP-506, Carboplatin, Immune checkpoint inhibitor - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 / Phase 2 | Recruiting | Maastricht University Medical Center | 126 | 2023-05-30 | 2025-10-07 |
| A Phase 1 Dose Escalation and Expansion Study Of SHR-1916 In Subjects With Locally Advanced Or Metastatic Solid Tumors SHR-1916 - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Terminated | Jiangsu HengRui Medicine Co., Ltd. | 11 | 2021-04-08 | 2024-02-09 |
| TR1801-ADC in Patients With Tumors That Express c-Met TR1801-ADC - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Suspended | Open Innovation Partners, Inc. | 15 | 2019-08-14 | 2023-09-22 |
| RNR Inhibitor COH29 in Treating Patients With Solid Tumors That Are Refractory to Standard Therapy or For Which No Standard Therapy Exists RNR inhibitor COH29, laboratory biomarker analysis, pharmacological study - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Active not recruiting | City of Hope Medical Center | 12 | 2017-01-09 | 2026-10-20 |
| A Phase 1/2 Multicenter Dose Escalation and Expansion Study Of NKTR-214 In Subjects With Locally Advanced Or Metastatic Solid Tumors NKTR-214 - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 / Phase 2 | Completed | Nektar Therapeutics | 28 | 2015-12-01 | 2021-07-29 |
| Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive Cancer radionuclide imaging, positron emission tomography, laboratory biomarker analysis - Breast Cancer, Colon Cancer | Not applicable | Active not recruiting | City of Hope Medical Center | 20 | 2015-11-11 | 2026-09-24 |
| Quantitative MRI in Assessing Disease in Patients With Brain Tumors diffusion-weighted magnetic resonance imaging, chemical exchange saturation transfer magnetic resonance imaging, dynamic contrast-enhanced magnetic resonance imaging - Tumors Metastatic to Brain, Unspecified Adult Solid Tumor, Protocol Specific | Not applicable | Terminated | Vanderbilt-Ingram Cancer Center | 10 | 2015-04-01 | 2018-05-29 |
| S1316, Surgery or Non-Surgical Management in Treating Patients With Intra-Abdominal Cancer and Bowel Obstruction therapeutic conventional surgery, gastrointestinal complications management/prevention, quality-of-life assessment - Constipation, Impaction, and Bowel Obstruction, Unspecified Adult Solid Tumor, Protocol Specific | Not applicable | Completed | SWOG Cancer Research Network | 221 | 2015-03-09 | 2023-03-30 |
| Dovitinib Lactate, Gemcitabine Hydrochloride, and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Solid Tumors or Pancreatic Cancer dovitinib lactate, gemcitabine hydrochloride, paclitaxel albumin-stabilized nanoparticle formulation - Duct Cell Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer | Phase 1 | Withdrawn | Roswell Park Cancer Institute | 2015-03-01 | 2015-01-09 | |
| APN401 in Treating Patients With Melanoma, Kidney Cancer, Pancreatic Cancer, or Other Solid Tumors That Are Metastatic or Cannot Be Removed By Surgery siRNA-transfected peripheral blood mononuclear cells APN401, laboratory biomarker analysis - Recurrent Melanoma, Recurrent Pancreatic Cancer | Phase 1 | Completed | Wake Forest University Health Sciences | 17 | 2014-12-01 | 2018-07-03 |
| Palliative Care Intervention in Improving Quality of Life, Psychological Distress, and Communication in Patients With Solid Tumors Receiving Treatment palliative care, quality-of-life assessment, survey administration - Unspecified Adult Solid Tumor, Protocol Specific | Not applicable | Completed | City of Hope Medical Center | 480 | 2014-09-17 | 2026-10-26 |
| VEGFR/PDGFR Dual Kinase Inhibitor X-82 and Docetaxel in Treating Patients With Solid Tumors VEGFR/PDGFR dual kinase inhibitor X-82, docetaxel, fluorine F 18 fluorothymidine - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | University of Wisconsin, Madison | 14 | 2014-09-01 | 2019-11-18 |
| Antiemetic Therapy With or Without Olanzapine in Preventing Chemotherapy-Induced Nausea and Vomiting in Patients With Cancer Receiving Highly Emetogenic Chemotherapy Olanzapine, Chemotherapy (cisplatin or cyclophosphamide and doxorubicin), Antiemetic treatment (ondansetron or granisetron or palonosetron; plus dexamethasone; plus fosaprepitant or aprepitant) - Hematopoietic/Lymphoid Cancer, Nausea and Vomiting | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 401 | 2014-08-20 | 2025-01-28 |
| Icotinib Hydrochloride in Treating Patients With Advanced Cancers icotinib hydrochloride, laboratory biomarker analysis, pharmacological study - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Withdrawn | Roswell Park Cancer Institute | 2014-08-01 | 2014-11-05 | |
| Genomic Profiling in Recommending Treatment for Patients With Metastatic Solid Tumors mutation analysis, cytology specimen collection procedure, laboratory biomarker analysis - Unspecified Adult Solid Tumor, Protocol Specific | Recruiting | Stanford University | 100 | 2014-07-28 | 2025-12-24 | |
| Gene-Modified T Cells, Vaccine Therapy, and Ipilimumab in Treating Patients With Locally Advanced or Metastatic Malignancies cyclophosphamide, fludarabine phosphate, NY-ESO-1 reactive TCR retroviral vector transduced autologous PBL - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Terminated | Jonsson Comprehensive Cancer Center | 4 | 2014-07-17 | 2019-02-28 |
| Cisplatin, Etoposide and PI3K Inhibitor BKM120 in Treating Patients With Advanced Solid Tumors or Small Cell Lung Cancer BKM120, cisplatin, etoposide - Extensive Stage Small Cell Lung Cancer, Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | University of California, Davis | 3 | 2014-07-01 | 2018-01-09 |
| Placebo-Controlled Therapeutic Trial for the Prevention of Lymphedema placebo for study drug, (RS)2-(3-benzoylphenyl)-propionic acid, laboratory biomarker analysis - Lymphedema, Unspecified Adult Solid Tumor, Protocol Specific | Not applicable | Terminated | Stanford University | 14 | 2014-04-01 | 2017-05-18 |
| PET-CT in Determining the Radioembolization Dose Delivered to Patients With Liver Metastasis, Primary Liver Cancer, or Biliary Cancer PET scan, CT Scan, hepatic artery embolization - Adult Primary Hepatocellular Carcinoma, Advanced Adult Primary Liver Cancer | Not applicable | Completed | Fox Chase Cancer Center | 44 | 2014-02-01 | 2026-07-02 |
| Propranolol Hydrochloride in Treating Patients With Locally Recurrent or Metastatic Solid Tumors That Cannot Be Removed By Surgery propranolol hydrochloride, Correlative Studies - Male Breast Cancer, Recurrent Melanoma | Early Phase 1 | Completed | William Carson | 1 | 2014-01-21 | 2022-12-06 |
Showing 20 of 758. Sign in to see all of them.
Leukemia, Lymphocytic, Chronic, B-Cell (119) · Lymphoma, Follicular (118) · Lymphoma, Non-Hodgkin (117) · Lymphoma, B-Cell, Marginal Zone (116) · Lymphoma, Mantle-Cell (116) · Lymphoma, Large B-Cell, Diffuse (115) · Burkitt Lymphoma (114) · Lymphoma, Large-Cell, Immunoblastic (114) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (114) · Hodgkin Disease (102) · Lymphoma (102) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (94) · Lymphoma, Large-Cell, Anaplastic (92) · Immunoblastic Lymphadenopathy (89) · Lymphoma, T-Cell, Cutaneous (82)
Neoplasms (282) · Pathological Conditions, Signs and Symptoms (228) · Neoplasms by Site (227) · Neoplasms by Histologic Type (198) · Pathologic Processes (163) · Hemic and Lymphatic Diseases (154) · Hematologic Diseases (149) · Immune System Diseases (135) · Immunoproliferative Disorders (133) · Lymphatic Diseases (131) · Disease Attributes (123) · Leukemia, Lymphoid (122) · Chronic Disease (121) · Leukemia, B-Cell (119) · Virus Diseases (118)
Paclitaxel (40) · Gemcitabine (39) · Irinotecan (39) · Cisplatin (36) · Carboplatin (33) · Docetaxel (30) · Bortezomib (22) · Capecitabine (21) · Fluorouracil (21) · Oxaliplatin (21) · Leucovorin (18) · Cyclophosphamide (17) · Filgrastim (17) · Psychiatric Rehabilitation (16) · alvocidib (16)
National Cancer Institute (NCI) (147) · Memorial Sloan Kettering Cancer Center (36) · Alliance for Clinical Trials in Oncology (34) · Case Comprehensive Cancer Center (27) · City of Hope Medical Center (26) · Mayo Clinic (22) · Roswell Park Cancer Institute (22) · National Institutes of Health Clinical Center (CC) (20) · European Organisation for Research and Treatment of Cancer - EORTC (17) · Jonsson Comprehensive Cancer Center (16) · University of California, Davis (14) · Wake Forest University Health Sciences (14) · NCIC Clinical Trials Group (13) · Northwestern University (11) · Barbara Ann Karmanos Cancer Institute (10)
United States (632) · Canada (35) · United Kingdom (29) · France (23) · Germany (15) · Belgium (14) · Netherlands (13) · Switzerland (13) · Norway (10) · Denmark (9) · Austria (8) · South Korea (5) · Spain (5) · Israel (4) · Italy (4)
Mario Sznol, MD (9) · Gary K. Schwartz, MD (8) · David R. Spriggs, MD (7) · Aminah Jatoi, MD (6) · George Wilding (6) · Alex Adjei (5) · Charles Erlichman (5) · Charles L. Loprinzi, MD (5) · Eric K. Rowinsky, MD (5) · Franco M. Muggia, MD (5) · Gary R. Morrow, PhD, MS (5) · Angela Davies, MD (4) · David R. Gandara, MD (4) · Debra Barton, RN, PhD, AOCN, FAAN (4) · Howard S. Hochster, MD (4)
PMID 20028764, PMID 39868569, PMID 10442378, PMID 10815886, PMID 10850352, PMID 11211153, PMID 11331328, PMID 11410496, PMID 11773155, PMID 12114401, PMID 12231519, PMID 12473581, PMID 12525514, PMID 12525530, PMID 12562658, PMID 12702532, PMID 12807934, PMID 12843799, PMID 12906958, PMID 12963697, PMID 14555506, PMID 14630685, PMID 14767498, PMID 15033677, PMID 15122073, PMID 15494606, PMID 15623609, PMID 15711184, PMID 15763645, PMID 15958629, PMID 15961763, PMID 16135477, PMID 16148284, PMID 16198982, PMID 16391300, PMID 16428495, PMID 16505427, PMID 16567769, PMID 16683073, PMID 16710026, PMID 17084620, PMID 17145828, PMID 17261851, PMID 17310049, PMID 17397698, PMID 17404091, PMID 17414457, PMID 17418968, PMID 17429623, PMID 17470735
P30CA043703 (23), U01CA062505 (22), P30CA015083 (17), P30CA033572 (17), U01CA062491 (17), U01CA062502 (15), P30CA014520 (13), U01CA062487 (12), U01CA069912 (12), P30CA022453 (11), P30CA093373 (9), U01CA099168 (9), U10CA031946 (9), U01CA069856 (8), P30CA006973 (7)