1589 completed, 346 unknown, 250 recruiting, 114 terminated. 1208 Not applicable, 279 Phase 3, 277 Phase 4, 234 Phase 2, 220 Phase 1.
Follow Type 2 Diabetes: new trials by email Literature Review of Type 2 Diabetes trials Research Report on Type 2 Diabetes
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MEDBRIDGE-Guided NCM/CHW Post-Discharge Support for High-Risk T2D Patients MEDBRIDGE-Guided NCM/CHW Post-Discharge Support Intervention - Type 2 Diabetes, Medication Adherence | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 45 | 2029-05-01 | 2026-05-20 |
| Implementation Support for HEARTS-Based Hypertension and Diabetes Care in Guatemala HEARTS implementation support, Routine HEARTS implementation - Hypertension (HTN), Type 2 Diabetes | Not applicable | Not yet recruiting | University of Michigan | 1440 | 2027-10-01 | 2026-11-12 |
| South Asians With Type 2 Diabetes at Risk for Depression CHW-led T2D Intervention - Type 2 Diabetes | Not applicable | Not yet recruiting | NYU Langone Health | 100 | 2027-08-01 | 2026-05-19 |
| Community Health Worker Nutrition Self-Management Support for Cardio-Kidney-Metabolic Health INTEGRATE-CHW, Usual Care - Hypertension (HTN), CKD - Chronic Kidney Disease | Not applicable | Not yet recruiting | Florida International University | 200 | 2027-07-15 | 2026-11-05 |
| Tracking Income Dynamics and Everyday Health Study Preventative health review invitation early in SNAP cycle, Financial counseling invitation early in the SNAP cycle, Aim 3 follow-up call early in the SNAP period - HIV, Hypertension | Not applicable | Not yet recruiting | University of Pennsylvania | 400 | 2027-03-01 | 2026-10-19 |
| Mindful Eating and Mindful Movement for Persons With Type 2 Diabetes Mellitus Standard of Care Diet and Exercise Group, Mindful Eating and Mindful Movement (MEMO) Group - Type 2 Diabetes | Not applicable | Not yet recruiting | Northeastern University | 60 | 2027-03-01 | 2026-09-18 |
| Adaptive Dietary Intervention (ADI) for Asian Americans With Type 2 Diabetes Continuous Glucose Monitoring (CGM), Adaptive dietary intervention (GEM) - Type 2 Diabetes | Not applicable | Not yet recruiting | NYU Langone Health | 120 | 2027-02-01 | 2026-08-13 |
| Insulin Icodec Initiation Strategies and Day-4 Supplemental Dosing in Type 2 Diabetes Insulin icodec - Type 2 Diabetes | Phase 4 | Not yet recruiting | Xi'an International Medical Center Hospital | 462 | 2027-01-01 | 2026-08-05 |
| Evaluation of Superiority of Valsartan+Celecoxib+Metformin Over Metformin Alone in Type 2 Diabetes Patients Metformin, Val, Cel and Met XR Low, Val, Cel and Met XR High - Type 2 Diabetes, High Blood Pressure | Phase 1 / Phase 2 | Withdrawn | ARKAY Therapeutics | 2026-12-10 | 2026-07-16 | |
| Efficacy of Topical Lidocaine Gel vs. Oral Duloxetine for Painful Diabetic Peripheral Neuropathy Topical Lidocaine 2% Gel, Duloxetine (60 MG) - Painful Diabetic Neuropathy (PDN), Diabetic Neuropathies | Phase 4 | Not yet recruiting | Wah Medical college , POF hospital | 80 | 2026-12-01 | 2026-09-02 |
| The LifeMeds Cohort Multimorbidity, Cancer | Not yet recruiting | Tilburg University | 2000 | 2026-12-01 | 2026-09-29 | |
| Relacorilant in Patients With Poorly Controlled Type 2 Diabetes and Autonomous Cortisol Secretion Relacorilant - Type 2 Diabetes, Hypercortisolism | Phase 1 / Phase 2 | Not yet recruiting | The University of Texas Health Science Center at San Antonio | 34 | 2026-12-01 | 2026-11-09 |
| Effect of Interactive Video-Based Self-Management Education in Adults With Type 2 Diabetes Interactive video training, Standard Nursing Care - Type 2 Diabetes, Outpatient | Not applicable | Not yet recruiting | Abant Izzet Baysal University | 60 | 2026-11-30 | 2026-10-09 |
| Peer Support and Remote Patient Monitoring for Black Adults With Type 2 Diabetes PROMOTE, DSMES - Type 2 Diabetes | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 200 | 2026-11-30 | 2026-10-30 |
| A Study to Learn More About How Well Finerenone Works in Real-world in People With Type 2 Diabetes and Chronic Kidney Disease in Primary Care (IMSS= Instituto Mexicano Del Seguro Social) Finerenone - Type 2 Diabetes, Chronic Kidney Disease (CKD) Stages G2 to G3b | Not yet recruiting | Bayer | 800 | 2026-11-30 | 2026-11-12 | |
| Effect of Molar Replacement on Glycemic Control in Adults With Uncontrolled Type 2 Diabetes Replacement of one pair of molars - Type 2 Diabetes | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 140 | 2026-11-15 | 2026-06-24 |
| AMBITION 3: A Research Study Investigating How Well Zenagamtide at Higher Dose Levels Lowers Blood Sugar and Body Weight Compared to Semaglutide in People With Type 2 Diabetes Treated With Metformin, SGLT2i, or Both Zenagamtide, Semaglutide, Placebo - Type 2 Diabetes | Phase 3 | Not yet recruiting | Novo Nordisk A/S | 1200 | 2026-11-10 | 2026-11-12 |
| A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes and Chronic Kidney Disease Treated With Once Daily Basal Insulin Alone or in Combination With Metformin, SGLT2i, or Both Placebo, Zenagamtide - Type 2 Diabetes, Chronic Kidney Disease | Phase 3 | Not yet recruiting | Novo Nordisk A/S | 450 | 2026-11-10 | 2026-11-12 |
| Inter-Arm Differences in Continuous Glucose Monitor Readings in Adults With Diabetes FreeStyle Libre 3 Plus Continuous Glucose Monitor - Continuous Glucose Monitoring, Type 1 Diabetes | Not applicable | Not yet recruiting | University of the Pacific | 60 | 2026-11-04 | 2026-11-05 |
| Efficacy of the Use of Real-time Continuous Glucose Monitoring on Glycemic Control in Patients With Type 2 Diabetes and Stage 3 and 4 Chronic Kidney Disease. Real time continuos glucose monitoring, self blood glucose monitoring - Type 2 Diabetes, Kidney Disease | Not applicable | Not yet recruiting | Hospital Universitario San Ignacio | 30 | 2026-11-01 | 2026-06-25 |
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Diabetes Mellitus, Type 2 (2587) · Diabetes Mellitus (355) · Obesity (337) · Insulin Resistance (181) · Motor Activity (100) · Overweight (100) · Cardiovascular Diseases (83) · Diabetes Mellitus, Type 1 (78) · Hypertension (78) · Prediabetic State (62) · Metabolic Syndrome (58) · Renal Insufficiency, Chronic (43) · Glucose Intolerance (42) · Inflammation (39) · Dyslipidemias (37)
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Metformin (135) · Sitagliptin Phosphate (77) · Insulin Glargine (63) · dapagliflozin (61) · Exercise (60) · semaglutide (51) · Pioglitazone (49) · Exenatide (47) · Liraglutide (45) · saxagliptin (33) · empagliflozin (32) · dulaglutide (28) · glimepiride (28) · Diet (24) · Insulin (24)
AstraZeneca (95) · Eli Lilly and Company (54) · Jiangsu HengRui Medicine Co., Ltd. (33) · Novo Nordisk A/S (24) · University of Aarhus (23) · University of Colorado, Denver (23) · Shanghai Jiao Tong University School of Medicine (20) · University of British Columbia (20) · Merck Sharp & Dohme LLC (19) · The University of Texas Health Science Center at San Antonio (19) · Brigham and Women's Hospital (15) · Emory University (15) · University Hospital, Gentofte, Copenhagen (15) · Assistance Publique - Hôpitaux de Paris (13) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (13)
United States (909) · China (254) · Canada (199) · Denmark (141) · United Kingdom (133) · Germany (102) · South Korea (99) · France (96) · Italy (86) · Mexico (86) · Turkey (Türkiye) (66) · India (65) · Sweden (55) · Australia (54) · Poland (52)
Daniela Jakubowicz, MD (8) · Deborah Price, MSc (7) · Guillermo Umpierrez, MD (7) · Ralph DeFronzo, MD (7) · Xiaoying Li, MD (6) · Adrian Vella, MD (5)
PMID 38770818, PMID 26894924, PMID 38682786, PMID 39963952, PMID 27402391, PMID 27461213, PMID 33368935, PMID 41591636, PMID 22913891, PMID 27306058, PMID 27964837, PMID 29974618, PMID 30117761, PMID 31301210, PMID 33436401, PMID 33512717, PMID 34131047, PMID 34135015, PMID 35210595, PMID 36938582, PMID 18663165, PMID 18852398, PMID 19017758, PMID 19114617, PMID 20859612, PMID 21228246, PMID 21932999, PMID 23435159, PMID 23451166, PMID 24400077, PMID 24912589, PMID 25414932, PMID 25927357, PMID 26303892, PMID 26441467, PMID 27407117, PMID 27514243, PMID 27627987, PMID 29802530, PMID 29923298, PMID 29941497, PMID 29941498, PMID 30475965, PMID 30550345, PMID 30632972, PMID 30765435, PMID 31114694, PMID 31178433, PMID 31364269, PMID 31589290
2023 (11), 2015 (7), 2019 (7), 2025 (5), 2016 (4), R01DK024092 (4), R01HL089637 (4), 2014 (3), 2018 (3), R01HL168858 (3), UL1RR024150 (3), 2005 (2), 2008 (2), 2009 (2), P50MD017338 (2)