11 terminated. 11 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 11 | Terminated 11 |
| Phase 2 | 4 | Terminated 4 |
Follow Type 1 Diabetes: new trials by email Literature Review of Type 1 Diabetes trials Research Report on Type 1 Diabetes
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Premixed Glucagon/Insulin Solution for Faster Insulin Absorption in Type 1 Diabetes Lyumjev 100 UNT/ML Injectable Solution, Premixed Lyumjev - Type 1 Diabetes | Phase 1 / Phase 2 | Terminated | St. Olavs Hospital | 9 | 2025-04-01 | 2026-10-19 |
| Study to Explore the Effect of Dapagliflozin and Stress in Adolescent and Adult Subjects With Type 1 Diabetes (T1D) Dapagliflozin, Placebo oral tablet, Stress - Type 1 Diabetes, Diabetic Ketoacidosis | Phase 1 | Terminated | Kinderkrankenhaus auf der Bult | 2 | 2022-05-18 | 2024-12-09 |
| Effect of ZT-01 on Glucagon During Hypoglycemia in Type 1 Diabetes Mellitus ZT-01 low dose, ZT-01 high dose, Placebo - Type 1 Diabetes, Hypoglycemia | Phase 1 | Terminated | Zucara Therapeutics Inc. | 24 | 2021-07-08 | 2023-07-12 |
| Glucagon Response to Prandial Insulin Administration in Persons With Type 1 Diabetes Insulin - Type 1 Diabetes, Hyperglycemia, Postprandial | Phase 1 / Phase 2 | Terminated | Washington University School of Medicine | 1 | 2020-02-13 | 2022-10-07 |
| Insulin Tolerance Test Study in Patients With Type 1 Diabetes Pitolisant - Type 1 Diabetes, Hypoglycemia | Phase 1 | Terminated | High Point Clinical Trials Center | 5 | 2019-09-15 | 2021-04-02 |
| A Study to Evaluate Safety, Engraftment, and Efficacy of VC-01 in Subjects With T1 Diabetes Mellitus VC-01 Combination Product - Type 1 Diabetes | Phase 1 / Phase 2 | Terminated | ViaCyte | 31 | 2019-06-25 | 2023-10-18 |
| Intra-nasal Naloxone for Treatment of Impaired Awareness of Hypoglycemia intra-nasal naloxone, Intra-nasal saline - Hypoglycemia Unawareness, Type 1 Diabetes | Phase 1 / Phase 2 | Terminated | University of Minnesota | 11 | 2016-06-01 | 2023-03-27 |
| Non Invasive Breath Based Acetone-meter- Easy Check Easy Check - Type 1 Diabetes | Phase 1 | Terminated | Rabin Medical Center | 6 | 2012-03-01 | 2018-05-15 |
| Effects of Metreleptin in Type 1 Diabetes Mellitus Leptin - Type 1 Diabetes | Phase 1 | Terminated | University of Texas Southwestern Medical Center | 8 | 2010-09-01 | 2019-08-28 |
| A Trial of 18F-AV-133 Positron Emission Tomography (PET) 18F-AV-133 - Type 1 Diabetes, Type 2 Diabetes | Phase 1 | Terminated | Avid Radiopharmaceuticals | 19 | 2010-06-01 | 2020-01-13 |
| DIATOR-Diabetes Intervention With Atorvastatin Atorvastatin, atorvastatin matching placebo - Type 1 Diabetes | Phase 1 | Terminated | Profil Institut für Stoffwechselforschung GmbH | 63 | 2004-03-01 | 2017-06-19 |
Diabetes Mellitus, Type 1 (11) · Hypoglycemia (3) · Diabetes Mellitus, Type 2 (1) · Diabetic Ketoacidosis (1) · Hyperglycemia (1)
Autoimmune Diseases (11) · Diabetes Mellitus (11) · Endocrine System Diseases (11) · Glucose Metabolism Disorders (11) · Immune System Diseases (11) · Metabolic Diseases (11) · Nutritional and Metabolic Diseases (11) · Acid-Base Imbalance (1) · Acidosis (1) · Diabetes Complications (1) · Ketosis (1)
Atorvastatin (1) · Insulin (1) · Leptin (1) · Naloxone (1) · adrenocorticotropin zinc (1) · dapagliflozin (1) · florbenazine F 18 (1) · metreleptin (1) · pitolisant (1)
Avid Radiopharmaceuticals (1) · High Point Clinical Trials Center (1) · Kinderkrankenhaus auf der Bult (1) · Profil Institut für Stoffwechselforschung GmbH (1) · Rabin Medical Center (1) · St. Olavs Hospital (1) · University of Minnesota (1) · University of Texas Southwestern Medical Center (1) · ViaCyte (1) · Washington University School of Medicine (1) · Zucara Therapeutics Inc. (1)
United States (6) · Germany (2) · Canada (1) · Israel (1) · Norway (1)
Abhimanyu Garg, M.D. (1) · Amir Moheet, MD (1) · Janet McGill, MD (1) · Manasi Jaiman, MD (1) · Melanie Fein, MD (1) · Moshe Phillip, Prof (1) · Richard Liggins, PhD (1) · Stefan Martin, MD (1) · Sven M Carlsen, MD PhD (1) · Torben Biester, MD (1)
PMID 21412424, PMID 22448235, PMID 23991111, PMID 42168649
2023 (1)