8 completed, 4 recruiting, 4 unknown. 11 Not applicable, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 5, Unknown 4, Recruiting 2 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
Follow Tourette Syndrome in Children: new trials by email Literature Review of Tourette Syndrome in Children trials Research Report on Tourette Syndrome in Children
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study on the Mechanism of Pei Tu Ning Feng Tang in Alleviating Tourette Syndrome Via Functional Near-Infrared Spectroscopy (fNIRS) and the DA-MAPK-BDNF Pathway Tourette Syndrome (TS) children were administered Pei Tu Ning Feng Tang treatment. - Tourette Syndrome in Children | Not applicable | Completed | Dongdong Qin | 60 | 2026-04-01 | 2026-10-01 |
| Investigating Changes in Premonitory Urges During Habit Reversal Training for Tics Habit Reversal Training - Tics, Tourette Disorder | Not applicable | Recruiting | University of Utah | 6 | 2025-02-11 | 2025-05-28 |
| Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders Sertraline, Placebo - Neurodevelopmental Disorders, Autism | Phase 2 | Recruiting | Holland Bloorview Kids Rehabilitation Hospital | 130 | 2024-09-16 | 2026-07-27 |
| Clinical Characteristics and Temporal Properties of Individual Tics in Persistent Tic Disorder Habit Reversal Training (HRT) - Tics, Tic Disorders | Not applicable | Unknown | University of Utah | 12 | 2024-04-04 | 2024-04-26 |
| Exploring the Role of Neuroactive Steroids in Tourette Syndrome Tic suppression task - Tourette Syndrome in Children | Not applicable | Recruiting | University of Utah | 120 | 2023-05-15 | 2026-10-06 |
| Tourette Discrimination (TD) Stigma Scale Tourette Syndrome, Tourette Syndrome in Children | Completed | Wake Forest University Health Sciences | 43 | 2023-03-04 | 2025-09-10 | |
| Peripheral Mechanisms of Humoral Immune Effector-mediated Tourette's Syndrome and the Role of Tuina Intervention Spine manipulation; westren medicine - Tourette Syndrome in Children, Food Intolerance | Not applicable | Unknown | The First Affiliated Hospital of Zhejiang Chinese Medical University | 50 | 2023-02-01 | 2024-04-23 |
| Theta Burst Stimulation to Improve Inhibitory Motor Physiology in Tourette Syndrome iTBS - Tourette Syndrome, Tourette Syndrome in Children | Not applicable | Completed | Children's Hospital Medical Center, Cincinnati | 16 | 2022-11-01 | 2026-03-18 |
| A Clinical Study to Evaluate the Safety and Efficacy of T92 in Pediatric Patients With Tourette Syndrome T92, Placebo - Tourette Syndrome in Children, Tourette Syndrome in Adolescence | Not applicable | Unknown | Tasly Pharmaceuticals, Inc. | 150 | 2022-05-01 | 2022-01-12 |
| Influence of Stress and Psychiatric Symptoms on Children With Tourette Syndrome Tourette Syndrome in Adolescence, Tourette Syndrome | Completed | Vanderbilt University Medical Center | 66 | 2021-03-29 | 2023-02-24 | |
| Transcranial Magnetic Stimulation to Augment Behavior Therapy for Tics Comprehensive Behavioral Intervention for Tics (CBIT), Repetitive Transcranial Magnetic Stimulation (rTMS), Continuous Theta Burst Stimulation (cTBS) - Tic Disorders, Tics | Not applicable | Completed | University of Minnesota | 50 | 2020-11-01 | 2025-03-07 |
| Ecopipam Tablets to Study Tourette Syndrome in Children and Adolescents - Open Label Extension Ecopipam - Tourette Syndrome in Children, Tourette Syndrome in Adolescence | Phase 2 | Completed | Emalex Biosciences Inc. | 124 | 2019-10-04 | 2024-02-01 |
| Internet-based CBIT for Children With Chronic Tics ICBIT, waiting list - Tourette Syndrome in Children, Tourette Syndrome in Adolescence | Not applicable | Unknown | Tel Aviv Medical Center | 40 | 2019-07-01 | 2019-09-12 |
| Extinction Learning in Youth With Tourette Syndrome Habit Reversal Training - Tourette Syndrome in Children, Tourette Syndrome in Adolescence | Not applicable | Completed | Johns Hopkins University | 20 | 2019-02-28 | 2023-08-08 |
| Evaluation of a Cognitive Psychophysiological Treatment for Tourette Syndrome and Tic Disorders Cognitive behavioural treatment for tics, Cognitive psychophysiological - Tic Disorder, Chronic Motor or Vocal, Tourette Syndrome in Children | Not applicable | Completed | Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal | 144 | 2016-04-21 | 2022-07-15 |
| The Findings of Magnetic Resonance Imaging in Subtypes of Tics-related Disorders Brain MRI - Tourette Syndrome in Children | Recruiting | National Taiwan University Hospital | 500 | 2015-10-20 | 2024-08-06 |
Tourette Syndrome (13) · Tic Disorders (6) · Tics (6) · 22q11 Deletion Syndrome (1) · Anxiety Disorders (1) · Attention Deficit Disorder with Hyperactivity (1) · Autism Spectrum Disorder (1) · Autistic Disorder (1) · DiGeorge Syndrome (1) · Food Intolerance (1) · Fragile X Syndrome (1) · Modifier, X-Linked, for Neurofunctional Defects (1) · Neurodevelopmental Disorders (1) · Social Stigma (1) · Tuberous Sclerosis (1)
Basal Ganglia Diseases (13) · Brain Diseases (13) · Central Nervous System Diseases (13) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (13) · Genetic Diseases, Inborn (13) · Heredodegenerative Disorders, Nervous System (13) · Mental Disorders (13) · Movement Disorders (13) · Nervous System Diseases (13) · Neurodegenerative Diseases (13) · Neurodevelopmental Disorders (12) · Neurologic Manifestations (7) · Pathological Conditions, Signs and Symptoms (7) · Signs and Symptoms (7) · Tic Disorders (7)
Behavior Therapy (1) · Manipulation, Spinal (1) · Selective Serotonin Reuptake Inhibitors (1) · Sertraline (1) · Therapeutics (1) · Transcranial Magnetic Stimulation (1) · Waiting Lists (1) · ecopipam (1)
University of Utah (3) · Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal (1) · Children's Hospital Medical Center, Cincinnati (1) · Dongdong Qin (1) · Emalex Biosciences Inc. (1) · Holland Bloorview Kids Rehabilitation Hospital (1) · Johns Hopkins University (1) · National Taiwan University Hospital (1) · Tasly Pharmaceuticals, Inc. (1) · Tel Aviv Medical Center (1) · The First Affiliated Hospital of Zhejiang Chinese Medical University (1) · University of Minnesota (1) · Vanderbilt University Medical Center (1) · Wake Forest University Health Sciences (1)
United States (10) · Canada (3) · China (2) · France (1) · Germany (1) · Israel (1) · Poland (1) · Taiwan (1)
Christine Conelea, PhD (1) · David A Isaacs, MD, MPH (1) · Dr. Evdokia Anagnostou (1) · Heather Riordan, MD (1) · Jaclyn M Martindale, DO (1) · Joseph F McGuire, PhD (1) · Marco Bortolato, MD PhD (1) · Michael H Bloch, MD, PhD (1) · Michael Himle, PhD (1) · Wang-Tso Lee (1)
PMID 33231786, PMID 37398344, PMID 37400828, PMID 41579326, PMID 42856611