5 completed, 3 terminated, 1 active not recruiting, 1 recruiting. 10 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Completed 5, Terminated 3, Active not recruiting 1, Recruiting 1 |
| Phase 2 | 1 | Active not recruiting 1 |
Follow Torulopsis: new trials by email Literature Review of Torulopsis trials Research Report on Torulopsis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis. Fosmanogepix, Caspofungin, Fluconazole - Candidemia, Candidiasis, Invasive | Phase 3 | Recruiting | Basilea Pharmaceutica | 450 | 2024-12-11 | 2026-10-19 |
| Ibrexafungerp for the Treatment of Complicated Vulvovaginal Candidiasis Ibrexafungerp - Vulvovaginal Candidiasis | Phase 3 | Completed | Scynexis, Inc. | 150 | 2022-05-01 | 2024-07-10 |
| Efficacy of Topical Treatment With Clobetasol in Symptomatic Oral Lichen Planus. Clobetasol Propionate, Placebo/Klobetasol APL oral gel 0.025%, Placebo - Oral Lichen Planus | Phase 2 / Phase 3 | Active not recruiting | Malmö University | 90 | 2020-05-18 | 2024-12-04 |
| Study to Compare the Efficacy and Safety of Micafungin Versus Conventional Amphotericin B for the Treatment of Neonatal Candidiasis micafungin, amphotericin B deoxycholate - Candidiasis | Phase 3 | Terminated | Astellas Pharma Global Development, Inc. | 30 | 2013-02-01 | 2015-11-04 |
| An Evaluation Of The Effectiveness And Safety Of Anidulafungin Compared To Caspofungin For The Treatment Of Serious Fungal Infection Due To Candida In Patients With A Dysfunctional Immune System Active Anidulafungin, Active Caspofungin - Fungemia, Neutropenia | Phase 3 | Terminated | Pfizer | 21 | 2009-08-01 | 2012-12-20 |
| An Evaluation Of The Effectiveness And Safety Of Anidulafungin Compared To Caspofungin For The Treatment Of Deep Tissue Infection Due To Candida Active anidulafungin, Active Caspofungin - Candidiasis, Fungemia | Phase 3 | Terminated | Pfizer | 41 | 2009-04-01 | 2013-08-01 |
| Fluconazole Prophylaxis for the Prevention of Candidiasis in Infants Less Than 750 Grams Birthweight fluconazole, placebo - Candidiasis | Phase 3 | Completed | Daniel Benjamin | 362 | 2008-11-01 | 2019-03-01 |
| Anidulafungin Candidemia/Invasive Candidiasis Intensive Care Study Anidulafungin, Fluconazole, Voriconazole - Invasive Candidiasis | Phase 3 | Completed | Pfizer | 216 | 2008-07-01 | 2011-05-30 |
| Caspofungin to Prevent Candidiasis in Adults in Hospital Intensive Care Units Caspofungin - Candidiasis | Phase 3 | Completed | National Cancer Institute (NCI) | 1200 | 2004-12-01 | 2008-03-04 |
| Anidulafungin Versus Fluconazole in the Treatment of Candidemia Anidulafungin - Candida, Candidiasis | Phase 3 | Completed | National Cancer Institute (NCI) | 248 | 2003-04-01 | 2008-03-04 |
Candidiasis (6) · Candidemia (5) · Mycoses (5) · Candidiasis, Invasive (4) · Fungemia (2) · Candidiasis, Vulvovaginal (1) · Invasive Fungal Infections (1) · Lichen Planus, Oral (1) · Neutropenia (1) · Systemic candidiasis (1)
Bacterial Infections and Mycoses (9) · Infections (9) · Inflammation (5) · Invasive Fungal Infections (5) · Pathologic Processes (5) · Pathological Conditions, Signs and Symptoms (5) · Sepsis (5) · Systemic Inflammatory Response Syndrome (5) · Mycoses (4) · Candidiasis (3) · Fungemia (3) · Agranulocytosis (1) · Candidiasis, Invasive (1) · Cytopenia (1) · Female Urogenital Diseases (1)
Fluconazole (3) · Anidulafungin (2) · Caspofungin (2) · Amphotericin B (1) · Clobetasol (1) · Injections (1) · Micafungin (1) · Voriconazole (1) · amphotericin B, deoxycholate drug combination (1) · ibrexafungerp (1)
Pfizer (3) · National Cancer Institute (NCI) (2) · Astellas Pharma Global Development, Inc. (1) · Basilea Pharmaceutica (1) · Daniel Benjamin (1) · Malmö University (1) · Scynexis, Inc. (1)
United States (7) · Belgium (3) · Bulgaria (3) · Canada (3) · France (3) · Greece (3) · Italy (3) · Romania (3) · Russia (3) · Austria (2) · Brazil (2) · Colombia (2) · Germany (2) · Hungary (2) · Israel (2)
Alexandra Hill, MD (1) · Daniel K Benjamin, MD MPH PhD (1) · Lori Tierney (1)
PMID 28459966, PMID 28597967, PMID 33891293, PMID 31280481, PMID 19915602, PMID 21961941, PMID 22026929, PMID 24794367, PMID 29596222, PMID 42163196
R01HD057956 (1)