22 completed, 2 recruiting, 2 terminated, 1 unknown. 28 Phase 2, 3 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 28 | Completed 22, Recruiting 2, Terminated 2, Unknown 1, Withdrawn 1 |
| Phase 1 | 3 | Completed 2, Terminated 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Teratoma: new trials by email Literature Review of Teratoma trials Research Report on Teratoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| High-dose Chemotherapy as Second-line Drug Therapy for Relapsed Germ Cell Tumors High-dose chemotherapy (TI- 2 cycles, CE- 3 cycles ) - Germ Cell Tumor | Phase 2 | Recruiting | N.N. Petrov National Medical Research Center of Oncology | 25 | 2024-03-01 | 2025-08-03 |
| A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT Biospecimen Collection, Carboplatin, Etoposide - Central Nervous System Nongerminomatous Germ Cell Tumor, Choriocarcinoma | Phase 2 | Recruiting | Children's Oncology Group | 160 | 2021-07-13 | 2026-09-23 |
| Vactosertib and Imatinib Combination in Patients with Advanced Desmoid Tumor/aggressive Fibromatosis (DT/AF) Vactosertib, Imatinib - Dermoid | Phase 2 | Withdrawn | MedPacto, Inc. | 2021-06-01 | 2024-12-09 | |
| A Randomized, Blinded, Placebo-controlled, Phase II Trial of LEE011 in Patients With Relapsed, Refractory, Incurable Teratoma With Recent Progression LEE011, LEE011 Placebo - Teratoma | Phase 2 | Completed | Novartis Pharmaceuticals | 10 | 2015-02-26 | 2020-10-26 |
| Palifosfamide in Treating Patients With Recurrent Germ Cell Tumors palifosfamide - Adult Central Nervous System Germ Cell Tumor, Adult Teratoma | Phase 2 | Terminated | Indiana University | 5 | 2013-02-01 | 2015-07-02 |
| Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer PD-0332991 - Adult Solid Tumor, Adenocarcinoma of the Colon | Phase 2 | Completed | Abramson Cancer Center at Penn Medicine | 304 | 2009-10-01 | 2021-03-11 |
| Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors carboplatin, dasatinib, etoposide phosphate - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 / Phase 2 | Terminated | City of Hope Medical Center | 7 | 2008-09-10 | 2026-11-04 |
| Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment sunitinib malate - Extragonadal Germ Cell Tumor, Ovarian Cancer | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 10 | 2007-03-01 | 2015-10-27 |
| Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors pegfilgrastim, cisplatin, ifosfamide - Brain and Central Nervous System Tumors, Extragonadal Germ Cell Tumor | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 60 | 2007-03-01 | 2017-11-28 |
| Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors carboplatin, etoposide, ifosfamide - Childhood Germ Cell Tumor, Ovarian Cancer | Phase 2 | Completed | Masonic Cancer Center, University of Minnesota | 23 | 2006-12-19 | 2022-05-17 |
| Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With Germ Cell Tumors That Did Not Respond to Cisplatin filgrastim, carboplatin, ifosfamide - Brain and Central Nervous System Tumors, Extragonadal Germ Cell Tumor | Phase 1 / Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 26 | 2006-08-01 | 2016-05-18 |
| Combination Chemotherapy in Treating Male Patients With Germ Cell Tumors bleomycin sulfate, carboplatin, cisplatin - Extragonadal Germ Cell Tumor, Teratoma | Phase 2 | Completed | Medical Research Council | 88 | 2005-06-01 | 2013-08-26 |
| Oxaliplatin in Treating Young Patients With Recurrent Solid Tumors That Have Not Responded to Previous Treatment oxaliplatin - Childhood Central Nervous System Germ Cell Tumor, Childhood Extragonadal Germ Cell Tumor | Phase 2 | Completed | National Cancer Institute (NCI) | 180 | 2004-10-01 | 2013-06-05 |
| Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors bleomycin sulfate, pegfilgrastim, cisplatin - Extragonadal Germ Cell Tumor, Teratoma | Phase 2 | Completed | Cambridge University Hospitals NHS Foundation Trust | 20 | 2004-08-01 | 2013-08-07 |
| Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors carboplatin, etoposide, ifosfamide - Brain Tumor, Central Nervous System Tumors | Phase 2 | Completed | Children's Oncology Group | 104 | 2004-01-01 | 2018-02-14 |
| Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors ixabepilone - Brain and Central Nervous System Tumors, Extragonadal Germ Cell Tumor | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 29 | 2003-08-01 | 2013-06-24 |
| Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors arsenic trioxide - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 22 | 2001-03-01 | 2015-11-25 |
| Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors filgrastim, recombinant interleukin-11 - Breast Cancer, Gestational Trophoblastic Tumor | Phase 2 | Completed | Fred Hutchinson Cancer Center | 2000-08-01 | 2010-04-02 | |
| Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon beclomethasone dipropionate - Breast Cancer, Chronic Myeloproliferative Disorders | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 2000-07-01 | 2010-04-02 | |
| Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell Tumors bleomycin sulfate, amifostine trihydrate, cisplatin - Childhood Germ Cell Tumor, Drug/Agent Toxicity by Tissue/Organ | Phase 2 | Completed | Children's Oncology Group | 27 | 2000-04-01 | 2013-07-04 |
Showing 20 of 28. Sign in to see all of them.
Testicular Neoplasms (22) · Carcinoma, Embryonal (15) · Endodermal Sinus Tumor (15) · Testicular Germ Cell Tumor (15) · Ovarian Neoplasms (14) · Seminoma (13) · Central Nervous System Neoplasms (9) · Neuroblastoma (8) · Wilms Tumor (7) · Breast Neoplasms (6) · Burkitt Lymphoma (6) · Dendritic Cell Sarcoma, Interdigitating (6) · Kidney Neoplasms (6) · Lymphoma, Large B-Cell, Diffuse (6)
Neoplasms by Histologic Type (28) · Neoplasms (27) · Neoplasms, Germ Cell and Embryonal (26) · Neoplasms by Site (24) · Urogenital Diseases (24) · Endocrine Gland Neoplasms (22) · Endocrine System Diseases (22) · Genital Diseases (22) · Genital Diseases, Male (22) · Genital Neoplasms, Male (22) · Gonadal Disorders (22) · Male Urogenital Diseases (22) · Testicular Diseases (22) · Urogenital Neoplasms (22) · Female Urogenital Diseases and Pregnancy Complications (18)
Ifosfamide (9) · Etoposide (8) · Carboplatin (7) · Cisplatin (7) · Filgrastim (7) · Paclitaxel (6) · Bleomycin (4) · Peripheral Blood Stem Cell Transplantation (4) · Radiotherapy (4) · Thiotepa (4) · etoposide phosphate (3) · pegfilgrastim (3) · Granulocyte Colony-Stimulating Factor (2) · Mesna (2) · Neoadjuvant Therapy (2)
Memorial Sloan Kettering Cancer Center (6) · Fred Hutchinson Cancer Center (4) · Children's Oncology Group (3) · City of Hope Medical Center (2) · Medical Research Council (2) · Abramson Cancer Center at Penn Medicine (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Cancer Treatment Centers of America (1) · European Organisation for Research and Treatment of Cancer - EORTC (1) · Indiana University (1) · Masonic Cancer Center, University of Minnesota (1) · Mayo Clinic (1) · MedPacto, Inc. (1) · N.N. Petrov National Medical Research Center of Oncology (1) · National Cancer Institute (NCI) (1)
United States (22) · United Kingdom (4) · Australia (3) · Canada (3) · Netherlands (3) · France (2) · New Zealand (2) · Spain (2) · Switzerland (2) · Austria (1) · Belgium (1) · Denmark (1) · Germany (1) · Hungary (1) · Israel (1)
Darren Feldman, MD (2) · Robert J. Motzer, MD (2) · Aleksei M Belyaev, MD,DSc,Prof. (1) · Anastasios Raptis, MD (1) · Brian H. Kushner, MD (1) · David Hockenbery, MD (1) · Dean F. Bajorin, MD (1) · Gnanamba V. Kondagunta, MD (1) · Ira Dunkel, MD (1) · Jan C. Buckner, MD (1) · Judith K. Sato, MD (1) · Lawrence H Einhorn, MD (1) · Leona A. Holmberg, MD, PhD (1) · Malcolm D. Mason, MD (1) · Mary E. D. Flowers, MD (1)
PMID 15999102, PMID 15999362, PMID 19547919, PMID 25001888, PMID 31545689, PMID 32641862, PMID 32692450
P30CA008748 (3), P30CA033572 (2), 2014 (1), P30CA015083 (1), U10CA098543 (1), U10CA180886 (1)