10 completed, 2 unknown, 1 active not recruiting, 1 recruiting. 15 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 15 | Completed 10, Unknown 2, Active not recruiting 1, Recruiting 1, Terminated 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Teratoma: new trials by email Literature Review of Teratoma trials Research Report on Teratoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors Best Practice, Biopsy Procedure, Biospecimen Collection - Childhood Extracranial Germ Cell Tumor, Extragonadal Embryonal Carcinoma | Phase 3 | Recruiting | Children's Oncology Group | 1780 | 2017-05-25 | 2026-08-25 |
| Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors paclitaxel, ifosfamide, cisplatin - Germ Cell Tumor, Teratoma | Phase 3 | Active not recruiting | Alliance for Clinical Trials in Oncology | 420 | 2015-08-06 | 2026-06-16 |
| Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy sodium thiosulfate, examination - Brain Tumor, Central Nervous System Tumor | Phase 3 | Completed | Children's Oncology Group | 131 | 2008-06-23 | 2023-11-09 |
| Observation and/or Combination Chemotherapy After Surgery or Biopsy in Treating Young Patients With Extracranial Germ Cell Tumors bleomycin sulfate, carboplatin, cisplatin - Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor | Phase 3 | Unknown | Children's Cancer and Leukaemia Group | 105 | 2005-05-01 | 2013-09-17 |
| Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors cisplatin, ifosfamide, paclitaxel - Extragonadal Germ Cell Tumor, Testicular Germ Cell Tumor | Phase 3 | Terminated | Alliance for Clinical Trials in Oncology | 1 | 2004-04-01 | 2016-07-04 |
| Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors bleomycin sulfate, cisplatin, etoposide - Extragonadal Germ Cell Tumor, Teratoma | Phase 3 | Completed | UNICANCER | 263 | 2003-11-26 | 2025-02-06 |
| Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors conventional surgery, cisplatin, etoposide - Childhood Embryonal Tumor, Childhood Extracranial Germ Cell Tumor | Phase 3 | Completed | Children's Oncology Group | 302 | 2003-11-03 | 2021-07-13 |
| Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment caspofungin acetate, liposomal amphotericin B - Cancer | Phase 3 | Completed | Memorial Sloan Kettering Cancer Center | 2000-08-01 | 2013-01-18 | |
| Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation captopril, cyclophosphamide, autologous bone marrow transplantation - Cancer | Phase 3 | Completed | Northwestern University | 35 | 1999-10-01 | 2012-06-06 |
| Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients liposomal amphotericin B - Cancer | Phase 3 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 115 | 1999-06-01 | 2012-09-24 |
| Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer bleomycin sulfate, filgrastim, cisplatin - Mediastinal Cancer, Metastatic Cancer | Phase 3 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 222 | 1999-04-01 | 2012-09-24 |
| Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation palivizumab, ribavirin - Cancer | Phase 3 | Completed | Fred Hutchinson Cancer Center | 1999-02-01 | 2010-04-02 | |
| Combination Chemotherapy in Treating Men With Germ Cell Cancer bleomycin sulfate, filgrastim, cisplatin - Extragonadal Germ Cell Tumor, Teratoma | Phase 2 / Phase 3 | Unknown | European Organisation for Research and Treatment of Cancer - EORTC | 498 | 1998-10-01 | 2012-03-06 |
| Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation fluconazole, itraconazole - Cancer | Phase 3 | Completed | Fred Hutchinson Cancer Center | 578 | 1998-10-01 | 2010-04-02 |
| Combination Chemotherapy With or Without Bone Marrow or Stem Cell Transplantation in Treating Men With Untreated Germ Cell Tumors bleomycin sulfate, filgrastim, carboplatin - Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor | Phase 3 | Completed | Memorial Sloan Kettering Cancer Center | 270 | 1994-09-01 | 2013-06-26 |
Endodermal Sinus Tumor (13) · Testicular Neoplasms (13) · Carcinoma, Embryonal (11) · Seminoma (10) · Teratoma, Testicular (7) · Neuroblastoma (6) · Blast Crisis (5) · Breast Neoplasms (5) · Burkitt Lymphoma (5) · Carcinoma, Ovarian Epithelial (5) · Hodgkin Disease (5) · Leukemia, Hairy Cell (5) · Leukemia, Lymphocytic, Chronic, B-Cell (5) · Leukemia, Myeloid, Accelerated Phase (5)
Neoplasms by Histologic Type (15) · Urogenital Diseases (14) · Endocrine Gland Neoplasms (13) · Endocrine System Diseases (13) · Genital Diseases (13) · Genital Diseases, Male (13) · Genital Neoplasms, Male (13) · Gonadal Disorders (13) · Male Urogenital Diseases (13) · Mesonephroma (13) · Neoplasms by Site (13) · Neoplasms, Germ Cell and Embryonal (13) · Testicular Diseases (13) · Urogenital Neoplasms (13) · Neoplasms (10)
Cisplatin (9) · Etoposide (8) · Bleomycin (7) · Ifosfamide (5) · Carboplatin (4) · Paclitaxel (4) · Filgrastim (3) · Peripheral Blood Stem Cell Transplantation (3) · Cyclophosphamide (2) · Radiotherapy (2) · Vinblastine (2) · liposomal amphotericin B (2) · 1,2-diaminocyclohexaneplatinum II citrate (1) · Biopsy (1) · Captopril (1)
Children's Oncology Group (3) · European Organisation for Research and Treatment of Cancer - EORTC (3) · Alliance for Clinical Trials in Oncology (2) · Fred Hutchinson Cancer Center (2) · Memorial Sloan Kettering Cancer Center (2) · Children's Cancer and Leukaemia Group (1) · Northwestern University (1) · UNICANCER (1)
United States (11) · Australia (5) · United Kingdom (5) · Belgium (4) · Canada (4) · France (4) · Germany (4) · Italy (4) · Netherlands (4) · Slovakia (4) · Spain (4) · Denmark (3) · Puerto Rico (3) · Switzerland (3) · Austria (2)
Robert J. Motzer, MD (2) · A. L Frazier (1) · Anne Frazier, MD (1) · Darren Feldman, MD (1) · David R. Freyer, DO, MS (1) · Eric J. Small, MD (1) · Gedske Daugaard, MD, DMSc (1) · Juliet Hale, MD (1) · Karim Fizazi, MD, PhD (1) · Kent Sepkowitz, MD (1) · Kieren A. Marr, MD (1) · Kim A. Margolin, MD (1) · Leo I. Gordon, MD (1) · Michael Boeckh, MD (1) · P. Ljungman, MD (1)
PMID 15459300, PMID 17235042, PMID 21059637, PMID 25456363, PMID 27914822, PMID 30563754, PMID 31355926, PMID 37783480, PMID 39028926, PMID 39167741
2005 (1), U10CA031946 (1), U10CA098543 (1), U10CA180821 (1), U10CA180886 (1)