11 completed, 4 unknown, 2 terminated, 1 active not recruiting. 5 Not applicable, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 3, Active not recruiting 1, Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 4 | 1 | Terminated 1 |
Follow Systemic Inflammatory Response Syndrome (SIRS): new trials by email Literature Review of Systemic Inflammatory Response Syndrome (SIRS) trials Research Report on Systemic Inflammatory Response Syndrome (SIRS)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Electroacupuncture at ST36 for Reducing Postoperative Inflammation After Cardiac Surgery With Cardiopulmonary Bypass Electroacupuncture at Bilateral ST36, Acupuncture Without Electrical Stimulation at Bilateral ST36 - Systemic Inflammatory Response Syndrome (SIRS), Cardiac Surgical Procedures | Not applicable | Recruiting | Sir Run Run Shaw Hospital | 140 | 2026-09-01 | 2026-09-08 |
| Implementation of Timely Management of Sepsis and Septic Shock Protocol in the Emergency Department and Intensive Care Unit: A Quality Improvement Project at AFHJ Adapted Surviving Sepsis Campaign (SSC) Protocol, Standard Clinical Care - Sepsis, Septic Shock | Not applicable | Completed | Al-Azhar University | 120 | 2026-03-03 | 2026-10-16 |
| Initial Feasibility Study of the CycloPE® Device PATH EX CycloPE® Device - Sepsis, Infection | Not applicable | Active not recruiting | PATH EX, Inc. | 15 | 2024-06-11 | 2025-05-14 |
| Effect of Lactiplantibacillus Plantarum DAD-13 on Inflammatory Markers in ICU Sepsis Patients Lactiplantibacillus plantarum DAD-13, Placebo - Sepsis, Systemic Inflammatory Response Syndrome (SIRS) | Not applicable | Completed | PT Royal Medikalink Pharmalab | 30 | 2024-04-01 | 2025-07-22 |
| Oxygen Delivery During Cardiopulmonary Bypass And Inflammatory Reaction After Cardiac Surgery Cardiopulmonary Bypass, Cardiac Surgery | Completed | Azienda Ospedaliero, Universitaria Ospedali Riuniti | 908 | 2023-10-30 | 2025-05-28 | |
| Myostatin and Irisin Levels in Predicting the Outcome of Patients With Systemic Inflammation: A Prospective Observational Study Systemic Inflammatory Response Syndrome (SIRS) | Completed | Charles University, Czech Republic | 54 | 2023-04-20 | 2026-03-17 | |
| Prediction of Inflammatory Response and Hypotensive Syndrome After Cardiac Surgery by Preoperative Copeptin Level Preoperative copeptin level - Systemic Inflammatory Response Syndrome (SIRS), Postoperative Vasodilation Syndrome | Completed | University Hospital, Montpellier | 200 | 2017-01-01 | 2017-09-25 | |
| Optimization of Therapeutic Human Serum Albumin Infusion in Selected Critically Ill Patients Human serum albumin infusion 4%, Human serum albumin infusion 20% - Shock, Systemic Inflammatory Response Syndrome (SIRS) | Phase 4 | Terminated | University Hospital, Strasbourg, France | 138 | 2016-09-01 | 2021-09-20 |
| The Analysis of Immuno-Nutrition Index in Advanced Gastric Cancer Receiving Preoperative Treatments Gastric Cancer, Neoadjuvant Chemotherapy | Unknown | Peking University | 600 | 2015-09-01 | 2018-04-11 | |
| VENUS: Septic Gene Expression Using SeptiCyte Sepsis, Systemic Inflammatory Response Syndrome (SIRS) | Completed | Immunexpress | 379 | 2014-04-01 | 2018-08-20 | |
| Systemic Inflammatory Response Syndrome (SIRS) in Patients Undergoing Major Procedures in Oral and Maxillofacial Surgery Systemic Inflammatory Response Syndrome (SIRS) | Completed | University of Cologne | 27 | 2013-09-01 | 2014-12-09 | |
| Application of Stimulated Immune Response Change to Predict Outcome of Patient With Severe Sepsis Systemic Inflammatory Response Syndrome (SIRS), Sepsis | Unknown | Chang Gung Memorial Hospital | 300 | 2013-07-01 | 2018-12-07 | |
| Application of Biomarkers Change to Predict Outcome of Patient With Severe Sepsis Systemic Inflammatory Response Syndrome (SIRS), Sepsis | Unknown | Chang Gung Memorial Hospital | 300 | 2013-07-01 | 2018-07-18 | |
| Lung and Systemic Inflammation in the Critically Ill Patient Acute Respiratory Distress Syndrome (ARDS), Systemic Inflammatory Response Syndrome (SIRS) | Terminated | Copenhagen University Hospital, Rigshospitalet | 8 | 2013-07-01 | 2018-12-11 | |
| Genotypes and Phenotypes in Pediatric SIRS and Sepsis Systemic Inflammatory Response Syndrome (SIRS), Sepsis | Completed | Seattle Children's Hospital | 104 | 2013-05-01 | 2018-04-19 | |
| Electronic Application of a Severe Sepsis Screening Tool and Management Bundle Severe Sepsis Management Bundle - Systemic Inflammatory Response Syndrome (SIRS), Sepsis | Unknown | University of Tennessee | 30000 | 2013-03-01 | 2015-03-31 | |
| Pharmacokinetic Study of Ceftaroline Fosamil/Avibactam in Adults With Augmented Renal Clearance Ceftaroline fosamil/Avibactam (CXL) - Augmented Renal Clearance (ARC), Systemic Inflammatory Response Syndrome (SIRS) | Phase 1 | Completed | Forest Laboratories | 12 | 2012-05-01 | 2017-04-07 |
| IMproved PREdiction of Severe Sepsis in the Emergency Department Systemic Inflammatory Response Syndrome (SIRS), Sepsis | Completed | Axis Shield Diagnostics Ltd | 759 | 2011-03-01 | 2017-04-14 | |
| Effects of Cardiopulmonary Bypass (CPB)-Leukocyte Filtration on Interleukins Serum Levels and Pulmonary Function Filtering group LG-6, Pall Biomedical Products - Systemic Inflammatory Response Syndrome (SIRS), Leukocyte Disorders | Not applicable | Completed | University of Sao Paulo | 22 | 2007-02-01 | 2011-11-10 |
Systemic Inflammatory Response Syndrome (19) · Sepsis (10) · Shock, Septic (5) · Critical Illness (4) · Inflammation (2) · Multiple Organ Failure (2) · Aneurysm (1) · Diabetes Insipidus (1) · Fractures, Stress (1) · Hypoalbuminemia (1) · Infections (1) · Leukocyte Disorders (1) · Postoperative Complications (1) · Respiratory Distress Syndrome (1) · Shock (1)
Pathologic Processes (19) · Pathological Conditions, Signs and Symptoms (19) · Shock (18) · Inflammation (17) · Infections (9) · Disease Attributes (4) · Hematologic Diseases (2) · Hemic and Lymphatic Diseases (2) · Blood Protein Disorders (1) · Cardiovascular Diseases (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Endocrine System Diseases (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1)
Acupuncture Therapy (1) · Ceftaroline (1) · Clinical Protocols (1) · Control Groups (1) · Leukocyte Reduction Procedures (1) · avibactam (1)
Chang Gung Memorial Hospital (2) · Al-Azhar University (1) · Axis Shield Diagnostics Ltd (1) · Azienda Ospedaliero, Universitaria Ospedali Riuniti (1) · Charles University, Czech Republic (1) · Copenhagen University Hospital, Rigshospitalet (1) · Forest Laboratories (1) · Immunexpress (1) · PATH EX, Inc. (1) · PT Royal Medikalink Pharmalab (1) · Peking University (1) · Seattle Children's Hospital (1) · Sir Run Run Shaw Hospital (1) · University Hospital, Montpellier (1) · University Hospital, Strasbourg, France (1)
United States (5) · China (2) · France (2) · Taiwan (2) · Armenia (1) · Australia (1) · Czechia (1) · Denmark (1) · Germany (1) · Indonesia (1) · Italy (1) · Saudi Arabia (1) · Sweden (1)
Adam Linder (1) · Anna Lange-Jendeberg (1) · Harutyun N Mangoyan, MD. PhD (1) · Jerry J Zimmerman, MD, PhD (1) · Jiafu Ji, M.D., Ph.D. (1) · Kanwaljeet S Anand, MBBS FCCM (1) · Magnus Paulsson (1) · Patrik Nyberg (1) · Philippe Gaudard, MD (1) · Russell R. Miller, MD, MPH (1) · Ryan Arnold (1) · Samir H Shah, MBBS MBA (1)
PMID 12720570, PMID 17334251, PMID 21669950, PMID 22073193, PMID 8700363, PMID 11825729, PMID 12131125, PMID 12682500, PMID 16676075, PMID 17015742, PMID 17167117, PMID 18501759, PMID 18552695, PMID 18594226, PMID 18954696, PMID 19373056, PMID 20979700, PMID 21153402, PMID 22026977, PMID 22610364, PMID 22998715, PMID 23117776, PMID 24562381, PMID 24576975, PMID 26468696, PMID 26645559, PMID 27655322, PMID 29624409, PMID 30221827, PMID 30828456, PMID 32791039, PMID 34646018, PMID 36004958, PMID 36342116, PMID 36630120, PMID 38000008, PMID 38897349, PMID 42565662, PMID 9631871