4 completed, 4 recruiting, 1 not yet recruiting, 1 unknown. 7 Not applicable, 1 Phase 1, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 4, Recruiting 2, Not yet recruiting 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 2 | 1 | Recruiting 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Smell Dysfunction: new trials by email Literature Review of Smell Dysfunction trials Research Report on Smell Dysfunction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effectiveness of Steroid Nasal Drops in the Olfactory Cleft Combined With Olfactory Training for Patients With PIOD Steroid nasal drops combined with olfactory training, Placebo nasal drops combined with olfactory training - Smell Dysfunction | Not applicable | Not yet recruiting | Peking University Third Hospital | 100 | 2026-03-01 | 2026-02-04 |
| Effects of Isotretinoin on Smell isotretinoin - Smell Dysfunction | Not applicable | Completed | Uşak University | 54 | 2025-06-01 | 2026-07-13 |
| Olfactory Biopsies olfactory testing, Odor stimulation, Olfactory biopsy - Alzheimer Disease, Smell Loss | Not applicable | Recruiting | Duke University | 125 | 2025-01-06 | 2026-06-12 |
| Ultramicronized Palmitoylethanolamide for Smell, Taste in Children With Autism Spectrum Disorder. supplement (Paidinil® HD, Epitech Group SpA, Saccolongo, Padova, Italy) containing 12% umPEA, Lactobacillus and Omega Fatty acids - Autism, Smell Dysfunction | Not applicable | Completed | University of Campania Luigi Vanvitelli | 80 | 2024-04-01 | 2026-06-08 |
| Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT for Long COVID) Trigeminal Nerve Stimulation (TNS), Active Smell Training (ST), Placebo Smell Training (PBO) - Smell Dysfunction, Olfactory Disorder | Phase 2 / Phase 3 | Recruiting | Medical University of South Carolina | 145 | 2023-10-02 | 2026-04-02 |
| Prospective Registery of Smell/Taste Clinic Ear/Nose/Throat Standard of care - Olfactory Disorder, Taste Disorders | Recruiting | Universitaire Ziekenhuizen KU Leuven | 500 | 2022-12-06 | 2025-12-18 | |
| Olfactory Training on Smell Dysfunction Patients in HK Olfactory Training, Control - Olfaction Disorders, Smell Disorders | Not applicable | Recruiting | Pamela Youde Nethersole Eastern Hospital | 80 | 2022-07-01 | 2025-06-03 |
| The Study of Quadruple Therapy Intranasal Insulin, Zinc, Gabapentin, Ice Cube Stimulation for Post COVID-19 Smell and Taste Dysfunctions Insulin aspart - Smell Dysfunction, Taste Disorders | Phase 1 | Unknown | Ministry of Health, Saudi Arabia | 22 | 2021-12-26 | 2021-11-03 |
| Post-Covid-19 Patients Follow-up Study Smell training - Smell Dysfunction, Taste Dysfunction | Not applicable | Completed | University of Oslo | 176 | 2021-04-01 | 2026-05-06 |
| Omega-3 Supplementation for Smell Dysfunction Omega-3 - Sellar/Parasellar Tumor, Smell Dysfunction | Not applicable | Completed | Stanford University | 110 | 2014-09-01 | 2018-08-21 |
Olfaction Disorders (10) · Anosmia (5) · Taste Disorders (3) · Alzheimer Disease (1) · Autistic Disorder (1) · COVID-19 (1) · Post-Acute COVID-19 Syndrome (1) · Sialorrhea (1)
Nervous System Diseases (10) · Neurologic Manifestations (10) · Pathological Conditions, Signs and Symptoms (10) · Sensation Disorders (10) · Signs and Symptoms (10) · Mental Disorders (2) · Autism Spectrum Disorder (1) · Brain Diseases (1) · Central Nervous System Diseases (1) · Child Development Disorders, Pervasive (1) · Chronic Disease (1) · Coronaviridae Infections (1) · Coronavirus Infections (1) · Dementia (1) · Disease Attributes (1)
Olfactory Training (4) · Docosahexaenoic Acids (1) · Insulin Aspart (1) · Isotretinoin (1) · Lacteol (1) · Standard of Care (1) · Transcutaneous Electric Nerve Stimulation (1) · Zinc (1)
Duke University (1) · Medical University of South Carolina (1) · Ministry of Health, Saudi Arabia (1) · Pamela Youde Nethersole Eastern Hospital (1) · Peking University Third Hospital (1) · Stanford University (1) · Universitaire Ziekenhuizen KU Leuven (1) · University of Campania Luigi Vanvitelli (1) · University of Oslo (1) · Uşak University (1)
United States (3) · Belgium (1) · China (1) · Hong Kong (1) · Italy (1) · Norway (1) · Turkey (Türkiye) (1)
Bradley Goldstein, MD, PhD (1) · Kai Chuen Fergus Wong, FRCSEd(ORL) (1) · Per Ole Iversen, PhD (1) · Zara M Patel, MD (1)
R01DC021179 (1), R01DC021422 (1)