9 completed, 9 unknown, 1 not yet recruiting. 3 Phase 2, 2 Phase 1, 1 Early Phase 1, 1 Not applicable, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Unknown 2, Completed 1 |
| Phase 1 | 2 | Completed 2 |
| Early Phase 1 | 1 | Unknown 1 |
| Not applicable | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Silicosis: new trials by email Literature Review of Silicosis trials Research Report on Silicosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Perioperative Risk Factors Related to the Prognosis of Lung Transplantation: A Retrospective Study COPD, Interstitial Pneumonia | Not yet recruiting | Zhejiang University | 250 | 2025-04-22 | 2025-04-22 | |
| Silicosis and Silicotuberculosis Among Small Scale Gemstone Miners in Northern Tanzania No intervention - Silicosis, Tuberculosis | Unknown | National Heart and Lung Institute | 1400 | 2024-03-11 | 2024-05-16 | |
| Using Silica 12CH to Mitigate the Effects and Symptoms of Silicosis in Brazil Silica 12CH - Silicosis | Early Phase 1 | Unknown | HOHM Foundation | 100 | 2024-03-01 | 2024-02-28 |
| Reducing Silica Exposure Among Brick Kiln Workers in Nepal N95 Respirator, Protective Eyewear, Baseline Survey - Silicosis | Not applicable | Completed | Johns Hopkins University | 98 | 2024-01-24 | 2024-06-24 |
| The SHIELD Study-silicosis Silicosis | Unknown | The University of Queensland | 120 | 2022-08-16 | 2022-09-21 | |
| Silicosis Treatment, Action, Screening and Surveillance in Rwanda Trials questionnaire, KAP - Silicosis, Silicotic Fibrosis (Massive) of Lung | Unknown | Samuel Hatfield | 995 | 2022-07-31 | 2022-09-22 | |
| The SHIELD Whole Lung Lavage Study Whole Lung Lavage - Silicosis | Unknown | The University of Queensland | 30 | 2022-06-01 | 2022-06-02 | |
| KAP TB in Senior Management Officials of Companies With Increased Silica Exposure TB - Tuberculosis, Silicosis | Completed | Centre for Infectious Disease Research in Zambia | 118 | 2022-02-02 | 2026-08-06 | |
| Pirfenidone for the Reduction of Metabolic, Inflammatory and Fibrogenic Activity in Complicated Silicosis Pirfenidone Oral Tablet - Silicosis, Progressive Massive Fibrosis | Phase 2 | Unknown | Instituto de investigación e innovación biomédica de Cádiz | 18 | 2021-11-15 | 2022-01-13 |
| The Nintedanib in Progressive Pneumoconiosis Study (NiPPS): a Collaborative NSW Treatment Trial Nintedanib 150 MG [Ofev] - Pneumoconiosis Coal, Asbestosis | Phase 2 | Unknown | Holdsworth House Medical Practice | 100 | 2020-10-09 | 2021-02-10 |
| Screening Strategy for Early Diagnosis of Silicosis in At-Risk Populations in Oklahoma Tuberculosis test, Chest X-ray, Pulmonary Function Test - Silicosis, Pneumoconiosis; Silica | Completed | University of Oklahoma | 183 | 2019-01-14 | 2023-12-06 | |
| Comprehensive Risk Assessment of People With Silicosis: A Population-based Study People with silicosis - Silicosis | Completed | Chinese University of Hong Kong | 390 | 2016-06-01 | 2018-07-06 | |
| Efficacy of Weekly Rifapentine and Isoniazid for Tuberculosis Prevention Weekly INH / RRT given by DOT - Silicosis, Tuberculosis | Phase 3 | Completed | Huashan Hospital | 566 | 2015-03-01 | 2020-06-30 |
| Oxidative Stress Biomarkers to Monitor and Early Detect Health Impairment in Workers Exposed to Silica (Caesar Stone) Silicosis | Unknown | Tel-Aviv Sourasky Medical Center | 150 | 2011-09-01 | 2011-04-19 | |
| DNA-damage Pathways in Workers Exposed to Silica (Caesar Stone) Silicosis | Unknown | Tel-Aviv Sourasky Medical Center | 150 | 2011-09-01 | 2011-04-05 | |
| Oscillation Mechanics of the Respiratory System in Never-smoking Patients With Silicosis Silicosis | Completed | Rio de Janeiro State University | 67 | 2010-07-01 | 2014-10-23 | |
| Safety Study of Autologous Bone Marrow Stromal Cells With Modification by Hepatocyte Growth Factor to Treat Silicosis Cells - Silicosis | Phase 1 / Phase 2 | Completed | Wei Yu | 10 | 2010-06-01 | 2013-11-25 |
| Safety of Stem Cells Intrabronchial Instillation for Silicosis Autologous cell transplantation - Chronic and Accelerated Silicosis | Phase 1 | Completed | Universidade Federal do Rio de Janeiro | 5 | 2009-08-01 | 2015-05-27 |
| Specialized Center of Research in Occupational and Immunologic Lung Disease Lung Diseases, Obstructive, Asbestosis | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 1972-06-01 | 2016-05-13 |
Pneumoconiosis (3) · Tuberculosis (3) · Asbestosis (2) · Lung Diseases (2) · Pulmonary Disease, Chronic Obstructive (2) · Anthracosis (1) · Behavior (1) · Bronchiectasis (1) · Bronchiolitis Obliterans Syndrome (1) · Hypertension, Pulmonary (1) · Idiopathic Pulmonary Fibrosis (1) · Infections (1) · Latent Tuberculosis (1) · Lung Diseases, Interstitial (1)
Lung Injury (19) · Occupational Diseases (19) · Respiratory Tract Diseases (19) · Lung Diseases, Interstitial (18) · Lung Diseases (17) · Pneumoconiosis (16) · Actinomycetales Infections (4) · Bacterial Infections (4) · Bacterial Infections and Mycoses (4) · Gram-Positive Bacterial Infections (4) · Mycobacterium Infections (4) · Infections (3) · Bronchial Diseases (2) · Chronic Disease (2) · Disease Attributes (2)
Surveys and Questionnaires (2) · Cell Count (1) · Diagnostic Imaging (1) · Isoniazid (1) · N95 Respirators (1) · Respiratory Function Tests (1) · Spirometry (1) · gp100 Melanoma Antigen (1) · nintedanib (1) · pirfenidone (1) · rifapentine (1)
Tel-Aviv Sourasky Medical Center (2) · The University of Queensland (2) · Centre for Infectious Disease Research in Zambia (1) · Chinese University of Hong Kong (1) · HOHM Foundation (1) · Holdsworth House Medical Practice (1) · Huashan Hospital (1) · Instituto de investigación e innovación biomédica de Cádiz (1) · Johns Hopkins University (1) · National Heart and Lung Institute (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · Rio de Janeiro State University (1) · Samuel Hatfield (1) · Universidade Federal do Rio de Janeiro (1) · University of Oklahoma (1)
Australia (3) · China (3) · United States (3) · Brazil (2) · Israel (2) · Nepal (1) · Rwanda (1) · Spain (1) · Tanzania (1) · Zambia (1)
Daniel Chambers (2) · Yehuda Shwartz, MD (2) · Alastair C Gray, PhD (1) · Antonio Campos Caro, phD (1) · Deborah Yates, A/Prof (1) · Hans Weill (1) · Innocent Kamali (1) · Jad Kebbe, MD (1) · Wenhong Zhang, MD,PhD (1) · William Checkley, MD, PhD (1)
PMID 12371452, PMID 17296674, PMID 23778400, PMID 24685414, PMID 26059242, PMID 26400297, PMID 28195659, PMID 28514023, PMID 31770617, PMID 32553881, PMID 33774816, PMID 34042560, PMID 35918725, PMID 40320069, PMID 42481393
D43TW009340 (1), P50HL015092 (1)