Perioperative Risk Factors Related to the Prognosis of Lung Transplantation: A Retrospective Study

Primary outcomes

• In-hospital adverse events [Collect data for an expected average about 2 hours]: In-hospital adverse events were defined as post-transplant complications occurring prior to discharge, such as: Grade 3 PGD, respiratory infections, stroke, cardiac events, AKI, or liver impairment.

Secondary outcomes

• ICU stay [Collect data for an expected average about 2 hours]: The ICU stay （days） was calculated from the time of ICU admission after surgery completion to actual discharge from the intensive care unit
• Postoperative hospital stay [Collect data for an expected average about 2 hours]: Postoperative hospital（days）stay after lung transplantation
• In-hospital mortality [Collect data for an expected average about 2 hours]: The proportion of patients who died during the initial hospitalization period following lung transplantation surgery
• 30-day postoperative mortality [Collect data for an expected average about 2 hours]: Number of deaths within 30 days post-transplant) / (Total number of lung transplant recipients) × 100%；
• 90-day postoperative mortality [Collect data for an expected average about 2 hours]: Number of deaths within 90 days post-transplant) / (Total number of lung transplant recipients) × 100%
• The duration of endotracheal intubation [Collect data for an expected average about 2 hours]: Duration of intubation should be recorded from surgery end-time to extubation

Other outcomes

• Grade 3 Primary Graft Dysfunction (PGD) [Collect data for an expected average about 2 hours]: PGD3:A ratio of arterial oxygen partial pressure to fraction of inspired oxygen (PaO₂/FiO₂) < 200 mmHg with bilateral infiltrates on chest radiograph, or Requirement for extracorporeal life support (ECLS) within 72 hours postoperatively, or use of inhaled pulmonary vasodilators for >48 hours during mechanical ventilation.
• Pulmonary Infection [Collect data for an expected average about 2 hours]: Radiologically confirmed by a staff radiologist as new or progressive pulmonary infiltrates on: Chest X-ray or Computed tomography (CT) scan
• Acute Kidney Injury [Collect data for an expected average about 2 hours]: A rise in serum creatinine >120 μmol/L
• Cardiovascular Events [Collect data for an expected average about 2 hours]: Acute myocardial infarction； heart failure；Cardiovascular hemorrhage；Clinically significant arrhythmias；Conduction system disorders；Cardiac arrest；Refractory hypotension due to cardiogenic sock.
• Hepatic Dysfunction [Collect data for an expected average about 2 hours]: Aspartate aminotransferase (AST) >34 or Alanine aminotransferase (ALT) >40 U/L;
• Cerebral Infarction [Collect data for an expected average about 2 hours]: Diagnosed by staff radiologists as new or progressive ischemic lesions on CT or MRI

Sex: All, ages: 18 Years to any

Inclusion Criteria:

* Age >18 years at time of transplantation
* Received single or bilateral lung transplantation

Exclusion Criteria:

* Re-transplantation
* Multi-organ transplantation
* Autotransplantation
* Incomplete medical records: Recipients with >20% missing essential data elements in any of these categories:Preoperative baseline characteristics； Intraoperative parameters；Postoperative outcome measures