43 completed. 43 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 43 | Completed 43 |
Follow Scleroderma, Diffuse: new trials by email Literature Review of Scleroderma, Diffuse trials Research Report on Scleroderma, Diffuse
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Personalized Online Occupational Therapy Intervention for Adults With Scleroderma Personalized Online Occupational Therapy Intervention, Usual Care - Scleroderma, Scleroderma (Limited and Diffuse) | Not applicable | Completed | Universidad de Zaragoza | 24 | 2026-05-16 | 2026-10-14 |
| Evaluating Tools to Communicate Scleroderma Research Results to Patients - Trial #1 Plain-language summary, Dissemination Tool (Infographic) - Scleroderma, Systemic Sclerosis | Not applicable | Completed | Lady Davis Institute | 511 | 2025-12-05 | 2026-09-10 |
| RENEW-AI: Personalizing Scleroderma Management With an AI Health Coach RENEW-AI - Scleroderma | Not applicable | Completed | University of Michigan | 20 | 2025-05-19 | 2025-08-20 |
| Evaluating the Effect of Questionnaire Context on the Reporting of Somatic Items Among People With Systemic Sclerosis Reordered PHQ-8 - Scleroderma, Systemic Sclerosis (SSc) | Not applicable | Completed | Lady Davis Institute | 851 | 2025-01-17 | 2025-09-09 |
| TENS in Scleroderma Transcutaneous Electrical Nerve Stimulation - Scleroderma, Gastroparesis | Not applicable | Completed | University of Michigan | 11 | 2024-10-01 | 2026-08-13 |
| Self-management Telehealth Program for Scleroderma self-management program, Video guide and usual education, Telephone notification, video guide and usual education - Scleroderma | Not applicable | Completed | Khon Kaen University | 72 | 2023-10-11 | 2025-05-30 |
| Stress, Scleroderma and Quality of Life Cognitive behavioral therapy - Scleroderma | Not applicable | Completed | Asociación Española de Esclerodermia | 150 | 2022-11-26 | 2024-02-01 |
| Phenotyping of Chronic Pain in Diffused Systemic Scleroderma QST, CPM and Paisudoscan - Scleroderma, Systemic, Scleroderma, Diffuse | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 100 | 2022-10-19 | 2024-12-04 |
| Quantification and Characterization of Circulating Epithelial and Endothelial Cells in Gougerot-Sjögren Syndrome, Compared to Systemic Sclerosis Blood sampling - Primary Gougerot-Sjögren Syndrome, Systemic Sclerosis, Diffuse | Not applicable | Completed | University Hospital, Montpellier | 40 | 2022-09-27 | 2025-09-30 |
| Scleroderma: Functional Disability Between the Dominant and Contralateral Hand. Measurement of joint amplitudes - Scleroderma, Systemic | Not applicable | Completed | University Hospital, Limoges | 30 | 2021-12-28 | 2026-03-27 |
| SPIN Self-Management Feasibility Trial With Progression to Full-scale Trial (SPIN-SELF) SPIN-SELF Program - Scleroderma, Systemic Sclerosis | Not applicable | Completed | Lady Davis Institute | 169 | 2021-09-15 | 2025-09-09 |
| Upper Extremity Home Exercises in Patients With Scleroderma Upper Extremity Home Exercises - Scleroderma, System; Sclerosis | Not applicable | Completed | Pamukkale University | 46 | 2021-09-10 | 2022-10-12 |
| RENEW Scleroderma: A Peer-Mentored, Web Intervention for Resilience-based, Energy Management to Enhance Wellbeing and Fatigue RENEW - Scleroderma | Not applicable | Completed | University of Michigan | 174 | 2021-08-28 | 2023-11-30 |
| Exercise With Scleroderma Functional Outcomes Exercise Program - Scleroderma, Systemic, Scleroderma, Diffuse | Not applicable | Completed | Trakya University | 44 | 2021-02-05 | 2024-05-22 |
| Optical Coherence Tomography Imaging in Systemic Sclerosis Non-invasive skin imaging assessment - Systemic Sclerosis, Early Systemic Sclerosis Without Clinical Scleroderma and Onset < 2 Years | Not applicable | Completed | University Hospital, Strasbourg, France | 60 | 2021-02-02 | 2023-08-14 |
| Telerehabilitation on Hand-Affected Scleroderma Hand Therapy via Telerehabilitation, Hand Therapy via home-exercises - Scleroderma, Scleroderma, Systemic | Not applicable | Completed | Istanbul University | 42 | 2021-01-06 | 2023-04-10 |
| Feasibility and Preliminary Effects of the Resilience-based, Energy Management to Enhance Wellbeing in Systemic Sclerosis (RENEW) Intervention Resilience-based, Energy Management to Enhance Wellbeing (RENEW) - Scleroderma | Not applicable | Completed | University of Michigan | 21 | 2020-10-27 | 2022-09-23 |
| The Effect of a Self-Management Program on Individuals With Scleroderma Self Management Intervention Program - Scleroderma, Systemic Sclerosis | Not applicable | Completed | Emirhan Karakuş | 29 | 2020-07-15 | 2023-10-23 |
| Evaluation of the Scleroderma Patient-centered Intervention Network COVID-19 Home-isolation Activities Together Program SPIN-CHAT Program - Scleroderma, Scleroderma, Systemic | Not applicable | Completed | Lady Davis Institute | 172 | 2020-04-09 | 2023-02-01 |
| Yoga Adjunct for Scleroderma Gentle Yoga and Yogic Breathing - Scleroderma | Not applicable | Completed | Medical University of South Carolina | 30 | 2020-01-08 | 2026-01-06 |
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Scleroderma, Systemic (28) · Motor Activity (4) · Anxiety Disorders (2) · Depression (2) · Gastroparesis (2) · Raynaud Disease (2) · Autoimmune Diseases (1) · COVID-19 (1) · Carpal Tunnel Syndrome (1) · Chronic Pain (1) · Connective Tissue Diseases (1) · Coronavirus Infections (1) · Disease (1) · Hand Deformities (1)
Skin Diseases (43) · Skin and Connective Tissue Diseases (43) · Connective Tissue Diseases (42) · Scleroderma, Systemic (15) · Behavior (7) · Pathological Conditions, Signs and Symptoms (7) · Pathologic Processes (4) · Cardiovascular Diseases (3) · Neurologic Manifestations (3) · Signs and Symptoms (3) · Vascular Diseases (3) · Behavioral Symptoms (2) · Digestive System Diseases (2) · Embolism and Thrombosis (2) · Fibrosis (2)
Rehabilitation (2) · Blood Specimen Collection (1) · Botulinum Toxins, Type A (1) · Cognitive Behavioral Therapy (1) · Methylprednisolone Acetate (1) · Occupational Therapy (1) · Ozone (1) · Physical Therapy Modalities (1) · Resistance Training (1) · Self-Management (1) · Starch (1) · Tablets (1) · Tai Ji (1) · Transcutaneous Electric Nerve Stimulation (1) · X-Rays (1)
Lady Davis Institute (9) · University of Michigan (7) · Assistance Publique - Hôpitaux de Paris (3) · Istanbul University (3) · Assiut University (2) · Pamukkale University (2) · Asociación Española de Esclerodermia (1) · Cukurova University (1) · Cytori Therapeutics (1) · Emirhan Karakuş (1) · Emory University (1) · Johns Hopkins University (1) · Khon Kaen University (1) · Medical University of South Carolina (1) · Region Skane (1)
United States (12) · Canada (9) · Turkey (Türkiye) (8) · France (6) · Spain (2) · Brazil (1) · Egypt (1) · Indonesia (1) · Sweden (1) · Thailand (1)
Brett D Thombs, PhD (2) · Brett Thombs, PhD (2) · Luc Mouthon, MD, PhD (2) · Susan Murphy (2) · Ayse Ayan, Dr (1) · Bertolo B Manoel, MD,PhD (1) · Chris Derk, MD, MSc (1) · Dinesh Khanna (1) · Dinesh Khanna, MD, MS (1) · Emmanuel Chatelus, MD (1) · Figen Yargucu Zihni, MD (1) · Harry Isbagio, MD, Prof. (1)
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