7 active not recruiting. 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Active not recruiting 7 |
Follow REM Sleep Behavior Disorder: new trials by email Literature Review of REM Sleep Behavior Disorder trials Research Report on REM Sleep Behavior Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| IMPACT 360 for Parkinson's Disease Exercise, Meditation, Diet - Parkinson's Disease (PD), REM Sleep Behavior Disorder | Phase 2 | Active not recruiting | University of British Columbia | 60 | 2024-10-28 | 2026-06-25 |
| Effect of PXS-4728A on Microglia Activation in Participants With Isolated Rapid Eye Movement Sleep Behaviour Disorder PXS-4728 (A), Matching Placebo (B) - REM Sleep Behavior Disorder | Phase 2 | Active not recruiting | Syntara | 40 | 2023-11-08 | 2026-06-02 |
| Terazosin and Parkinson's Disease Extension Study Terazosin therapy - Symptomatic Parkinson Disease, REM Sleep Behavior Disorder | Phase 2 | Active not recruiting | Cedars-Sinai Medical Center | 15 | 2022-09-23 | 2026-03-02 |
| Terazosin Effect on Cardiac Changes in Early Parkinson's Disease Terazosin - REM Sleep Behavior Disorder, Pre-motor Parkinson's Disease | Phase 2 | Active not recruiting | Cedars-Sinai Medical Center | 15 | 2020-11-01 | 2026-03-02 |
| A Clinical Study of the Efficacy of Idebenone in the Treatment of iRBD Into Synucleinopathies Idebenone, Placebo - Rapid Eye Movement Sleep Behavior Disorder, Synucleinopathy | Phase 2 | Active not recruiting | Ruijin Hospital | 28 | 2020-08-31 | 2025-11-25 |
| Cardiac Changes in Early Parkinson's Disease: A Follow up Study Carvedilol - REM Sleep Behavior Disorder, Pre-motor Parkinson Disease | Phase 2 | Active not recruiting | Cedars-Sinai Medical Center | 15 | 2019-12-30 | 2026-03-02 |
| Adrenergic Blockers for Cardiac Changes in Early Parkinson's Disease (Protocol 53136) Carvedilol - REM Sleep Behavior Disorder, Pre-motor Parkinson Disease | Phase 2 | Active not recruiting | Michele Tagliati, MD | 15 | 2019-04-04 | 2026-03-02 |
Parkinson Disease, Secondary (4) · Parkinson Disease (3) · Nerve Degeneration (2) · Primary Dysautonomias (2) · Motor Activity (1) · Synucleinopathies (1)
Mental Disorders (7) · Nervous System Diseases (7) · Parasomnias (7) · REM Sleep Parasomnias (7) · Sleep Wake Disorders (7) · Basal Ganglia Diseases (5) · Brain Diseases (5) · Central Nervous System Diseases (5) · Movement Disorders (5) · Parkinsonian Disorders (5) · Neurodegenerative Diseases (4) · Synucleinopathies (3) · Autonomic Nervous System Diseases (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2)
Carvedilol (2) · Diet (1) · Exercise (1) · Meditation (1) · Terazosin (1) · idebenone (1)
Cedars-Sinai Medical Center (3) · Michele Tagliati, MD (1) · Ruijin Hospital (1) · Syntara (1) · University of British Columbia (1)
United States (4) · Australia (1) · Canada (1) · China (1) · United Kingdom (1)
Michele Tagliati, MD, FAAN (2) · Michele L Lima Gregorio, MD, FAAN (1) · Michele L Tagliati, MD (1) · Silke Appel-Cresswell, MD, FRCPC (1)
PMID 10214756, PMID 10406987, PMID 10527042, PMID 10853813, PMID 10979878, PMID 11076832, PMID 11400186, PMID 11724917, PMID 12498954, PMID 12904089, PMID 15175402, PMID 15345186, PMID 15645531, PMID 15779234, PMID 16025231, PMID 16442563, PMID 16715205, PMID 16837857, PMID 17190953, PMID 18079166, PMID 18349024, PMID 19018276, PMID 20146689, PMID 20188504, PMID 20846908, PMID 20887968, PMID 20976736, PMID 21045744, PMID 21421334, PMID 21538520, PMID 21571570, PMID 21700495, PMID 21802993, PMID 22321865, PMID 22483040, PMID 22508280, PMID 23024438, PMID 23160999, PMID 23266935, PMID 23329524, PMID 23347909, PMID 23562390, PMID 23647842, PMID 23970363, PMID 24332912, PMID 24637128, PMID 25483722, PMID 25589269, PMID 25666029, PMID 25681454