9 completed. 9 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Completed 9 |
Follow Refractory Epilepsy: new trials by email Literature Review of Refractory Epilepsy trials Research Report on Refractory Epilepsy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Investigating the Role and Electrophysiological Characteristics of the Human Claustrum Based on SEEG Direct Electrical Stimulation - Refractory Epilepsy, Consciousness, Loss of | Not applicable | Completed | Xuanwu Hospital, Beijing | 8 | 2024-05-27 | 2025-07-11 |
| Optimal Stimulation Parameters to Disrupt Epileptiform Activity Neurostimulation - Refractory Epilepsy | Not applicable | Completed | Massachusetts General Hospital | 16 | 2023-06-13 | 2026-09-02 |
| Modulation of Emotion Perception in Humans Via Amygdala Stimulation Electrical Stimulation - Refractory Epilepsy | Not applicable | Completed | Dartmouth-Hitchcock Medical Center | 16 | 2022-03-31 | 2025-09-22 |
| Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy STARSTIM device, Sham Device - Refractory Epilepsy, Focal Seizure | Not applicable | Completed | Neuroelectrics Corporation | 127 | 2021-10-25 | 2026-04-08 |
| The Potential of a Low Glutamate Diet as a Treatment for Pediatric Epilepsy Low Glutamate diet - Epilepsy in Children, Epilepsy in Youth | Not applicable | Completed | American University | 45 | 2020-10-15 | 2022-07-20 |
| Safety of Using NaviFUS System in Patients With Drug Resistant Epilepsy NaviFUS System - Drug Resistant Epilepsy, Epilepsy, Drug Resistant | Not applicable | Completed | NaviFUS Corporation | 6 | 2019-06-17 | 2020-11-13 |
| Acute and Long Term Effects of VNS on Memory in Patients With Refractory Epilepsy Memory task - Refractory Epilepsy | Not applicable | Completed | University Hospital, Ghent | 16 | 2018-11-22 | 2023-05-06 |
| Safety and Therapeutic Measures of Tdcs in Patients With Refractory Focal Epilepsy Cathodal Transcranial Direct Current Stimulation (tDCS). - Refractory Epilepsy | Not applicable | Completed | Neuroelectrics Corporation | 20 | 2017-09-21 | 2021-01-11 |
| Clinical Utility of ESI in Presurgical Evaluation of Patients With Epilepsy Low-density ESI (LD ESI), High-density ESI (HD ESI), No electrical source imaging (ESI) - Electroencephalography, Refractory Epilepsy | Not applicable | Completed | Copenhagen University Hospital, Rigshospitalet | 82 | 2015-12-02 | 2019-03-27 |
Drug Resistant Epilepsy (9) · Epilepsy (1) · Epilepsy, Tonic-Clonic (1) · Mental Disorders (1) · Seizures (1) · Unconsciousness (1)
Brain Diseases (9) · Central Nervous System Diseases (9) · Nervous System Diseases (9) · Epilepsy (8) · Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Consciousness Disorders (1) · Epilepsy, Generalized (1) · Neurobehavioral Manifestations (1)
Transcranial Direct Current Stimulation (2) · Electric Stimulation (1)
Neuroelectrics Corporation (2) · American University (1) · Copenhagen University Hospital, Rigshospitalet (1) · Dartmouth-Hitchcock Medical Center (1) · Massachusetts General Hospital (1) · NaviFUS Corporation (1) · University Hospital, Ghent (1) · Xuanwu Hospital, Beijing (1)
United States (5) · Belgium (2) · China (1) · Denmark (1) · France (1) · Spain (1) · Taiwan (1)
Catherine Chu, MD (1) · Hsiang-Yu Yu, M.D. (1) · Kathleen Holton, MPH, PhD (1) · Krzysztof A Bujarski, MD (1) · Liankun Ren (1) · Olaf B Paulson, MD, DMSc (1)
PMID 35132096, PMID 36867910, PMID 42401244
R01NS119483 (1), R21MH124674 (1)