11 completed, 7 unknown, 1 active not recruiting, 1 recruiting. 11 Not applicable, 6 Phase 2, 2 Phase 3, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 5, Unknown 5, Recruiting 1 |
| Phase 2 | 6 | Completed 5, Terminated 1 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
| Early Phase 1 | 1 | Unknown 1 |
Follow Pulp Necroses: new trials by email Literature Review of Pulp Necroses trials Research Report on Pulp Necroses
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lesion Sterilization Tissue Repair and Conventional Pulpectomy in Primary Molars Lesion sterilization and tissue repair, Conventional pulpectomy - Pulpitis - Irreversible, Pulp Necroses | Active not recruiting | Çanakkale Onsekiz Mart University | 59 | 2025-10-01 | 2026-10-07 | |
| Bacterial Load Reduction by GentleWave and EdgePro Irrigation Systems in Mandibular Necrotic Molars GentleWave, EdgePro laser irrigation, Irrisafe passive ultrasonic irrigation - Pulp Necroses | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 30 | 2024-08-30 | 2025-09-05 |
| Postoperative Pain After Conservative Root Canal Preparation Root Canal Treatment with ProTaper Next Nickel-Titanium File (PTN), Root Canal Treatment withTruNatomy Nickel-Titanium File (TN) - Periapical Diseases, Periapical Periodontitis | Not applicable | Completed | Istanbul University | 90 | 2024-03-04 | 2024-10-18 |
| Influence of Moment of Restoration in Pain After a Root Canal Treatment root canal treatment - Irreversible Pulpitis, Pulp Necroses | Not applicable | Unknown | Universitat Internacional de Catalunya | 60 | 2023-11-14 | 2024-01-31 |
| The Efficacy and Safety of Pulp Regeneration Induced by SHED Polymerization Allogeneic human pulp mesenchymal stem cells mixed with hyaluronic acid polymers - Pulp Necroses | Not applicable | Unknown | Fifth Affiliated Hospital of Guangzhou Medical University | 30 | 2023-09-01 | 2023-08-28 |
| Assessment of Post-operative Pain After Different Instrumentation Techniques in Pulpectomy Treatment of Primary Molars pulpectomy treatment will be done using the adaptive xp endo shaper., pulpectomy treatment will be done using FANTA AF baby files., pulpectomy treatment will be done using hand k files. - Pulp Necroses | Not applicable | Unknown | Mansoura University | 75 | 2023-08-10 | 2024-02-13 |
| Histopathological Evaluation of the Periodontal Ligament Subjected to Laser Ablation. Laser and ICG solution. - Pulp Necroses | Not applicable | Completed | CAO Group, Inc. | 10 | 2023-08-01 | 2024-02-29 |
| Cell-free Autologous Regenerative Endodontics Treatment for Teeth With Periapical Lesions (CARETT) Autologous Regenerative Endodontic Treatment, Conventional Root Canal Treatment - Periapical Diseases, Pulp Necroses | Not applicable | Unknown | Universidad de Valparaiso | 228 | 2023-03-01 | 2022-03-31 |
| Zincoxide-propolis vs Zincoxide-eugenol Pulpectomy Zinc oxide Propolis, Zinc Oxide-Eugenol Cement - Pulp Necroses | Early Phase 1 | Unknown | Cairo University | 38 | 2022-04-01 | 2022-02-09 |
| The Efficacy of Laser in Root Canal Disinfection Conventional group (NaOCl/EDTA), Dual laser group (Er,Cr:YSGG/Diode):, Combined group (EDTA/Diode): - Pulp and Periapical Tissue Disease, Pulp Necroses | Phase 2 | Completed | Future University in Egypt | 30 | 2022-01-01 | 2023-11-29 |
| "Postoperative Pain Following Laser-Assisted Root Canal Treatment: A Randomized Clinical Trial" Conventional group, Dual laser group, Combined group - Pulp Necroses, Apical Periodontitis | Phase 2 | Completed | Future University in Egypt | 45 | 2022-01-01 | 2026-06-30 |
| Comparison Between Two Regenerative Scaffolds Endodontic regeneration using concentrated growth factor compared with Platelet rich fibrin - Pulp Necroses | Not applicable | Completed | Faculty of Dental Medicine for Girls | 18 | 2021-11-01 | 2024-01-29 |
| Post Operative Pain Assessment After Pulpectomy of Primary Molars With Two Different Rotary Systems Pulpectomy using single file system ( One Shape file), Pulpectomy using single file system ( WaveOne Gold file) - Pulp Necroses | Not applicable | Completed | Minia University | 164 | 2021-01-10 | 2021-09-27 |
| Accuracy of Apex Locators in Primary Teeth working length determination techniques - Endodontically Treated Teeth, Primary Teeth | Completed | Eskisehir Osmangazi University | 30 | 2020-10-17 | 2020-11-20 | |
| Treatment of Infected Pulp in Primary Teeth With a Mixture of Calcium Hydroxide and Gingerols Ginge-Cal, Metapex - Primary Teeth, Pulp Necroses | Not applicable | Completed | Mansoura University | 30 | 2020-10-17 | 2023-01-10 |
| Transplantation of Allogeneic MSC in Patients With Pulp Necrosis and Chronic Apical Periodontitis Allogenic transplant of BM-MSC in a root canal from patients with immature apexes and pulpar necrosis and apical periodontitis - Pulp Necroses, Apical Periodontitis | Phase 2 / Phase 3 | Completed | Universidad Central de Venezuela | 5 | 2019-11-27 | 2020-09-16 |
| Laser Activated Irrigation Versus Passive Ultrasonic Irrigation Laser activated irrigation, Passive ultrasonic irrigation - Pulp Necroses | Not applicable | Unknown | Cairo University | 44 | 2019-09-01 | 2019-07-30 |
| Microbiological Evaluation of Single Versus Multiple Visits Regeneration Using MALDI-TOF Mass Spectrometry Single-visit regeneration protocol, Multiple-visits regeneration protocol - Pulp Necroses, Tooth, Nonvital | Phase 2 | Terminated | Nourhan M.Aly | 16 | 2018-08-23 | 2022-03-29 |
| Efficacy of Combined Blood Clot and Platelet Rich Fibrin Scaffolds in Regeneration of Necrotic Immature Permanent Teeth Blood clot scaffold, Blood clot scaffold combined with PRF - Pulp Necroses | Phase 2 | Completed | Nourhan M.Aly | 30 | 2018-07-06 | 2020-11-04 |
| Revascularization of Immature Anterior Necrotic Teeth intracanal disinfection in revascularization - Pulp Necroses | Phase 3 | Unknown | Cairo University | 56 | 2018-06-01 | 2018-04-20 |
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Dental Pulp Necrosis (21) · Pain, Postoperative (3) · Periapical Periodontitis (3) · Periapical Diseases (2) · Tooth, Nonvital (2) · Dental Pulp Diseases (1) · Granuloma (1) · Pain (1) · Symptom Flare Up (1)
Necrosis (21) · Pathologic Processes (21) · Pathological Conditions, Signs and Symptoms (21) · Stomatognathic Diseases (21) · Tooth Diseases (21) · Dental Pulp Diseases (20) · Jaw Diseases (4) · Mouth Diseases (4) · Periodontal Diseases (4) · Neurologic Manifestations (3) · Periodontitis (3) · Postoperative Complications (3) · Signs and Symptoms (3) · Pain (2) · Periapical Diseases (2)
Lasers (1) · Metapex (1) · Prolactin-Releasing Hormone (1) · Wound Healing (1) · Zinc Oxide-Eugenol Cement (1)
Cairo University (3) · Future University in Egypt (2) · Mansoura University (2) · Nourhan M.Aly (2) · Alexandria University (1) · CAO Group, Inc. (1) · Eskisehir Osmangazi University (1) · Faculty of Dental Medicine for Girls (1) · Fifth Affiliated Hospital of Guangzhou Medical University (1) · Istanbul University (1) · Minia University (1) · The University of Texas Health Science Center, Houston (1) · Universidad Central de Venezuela (1) · Universidad de Valparaiso (1) · Universitat Internacional de Catalunya (1)
Egypt (9) · Turkey (Türkiye) (3) · Brazil (1) · Spain (1) · United States (1) · Venezuela (1)
Alicia Caro, MSC, DDS (1) · Ashraf M Zaazou, PhD (1) · Berkant Sezer, Assoc. Prof. (1) · David Jaramillo, DDS (1) · Fathi A Qasem, PhD (1) · Juan Caro, DDS (1) · Mahmoud MS Hassan, M.Sc (1) · Mohamed Ibrahim, PhD (1) · Nihal A Lehita, PhD (1) · Pervine H. Sharaf, M.Sc (1) · Raef A Sherif, PhD (1) · Rania M ElBackly, PhD (1) · Rizk A ELagamy, PhD (1)