2 completed, 1 terminated. 2 Phase 4, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 2 | Completed 1, Terminated 1 |
| Phase 3 | 1 | Completed 1 |
Follow Pseudobulbar Affect (PBA): new trials by email Literature Review of Pseudobulbar Affect (PBA) trials Research Report on Pseudobulbar Affect (PBA)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety, Tolerability and Effectiveness of Nuedexta in the Treatment of Pseudobulbar Affect (PBA) Nuedexta (DM 20 mg/Q 10 mg) - Pseudobulbar Affect (PBA), Stroke | Phase 4 | Completed | Avanir Pharmaceuticals | 367 | 2013-02-01 | 2017-03-15 |
| Nuedexta in the Treatment of Pseudobulbar Affect in Patients With Alzheimer's Disease Nuedexta (20/10) - Alzheimer's Disease, Pseudobulbar Affect (PBA) | Phase 4 | Terminated | St. Joseph's Hospital and Medical Center, Phoenix | 34 | 2012-08-28 | 2019-10-29 |
| Safety and Efficacy of AVP-923 in PBA Patients With ALS or MS dextromethorphan hydrobromide 20 mg and quinidine sulfate 10 mg, dextromethorphan hydrobromide 30 mg and quinidine sulfate 10 mg, Placebo - Pseudobulbar Affect (PBA) | Phase 3 | Completed | Avanir Pharmaceuticals | 326 | 2007-12-01 | 2017-04-12 |
Alzheimer Disease (1) · Amyotrophic Lateral Sclerosis (1) · Brain Injuries, Traumatic (1) · Dementia (1) · Multiple Sclerosis (1) · Stroke (1)
Central Nervous System Diseases (3) · Nervous System Diseases (3) · Brain Diseases (2) · Mental Disorders (2) · Neurocognitive Disorders (2) · Neurodegenerative Diseases (2) · Autoimmune Diseases (1) · Autoimmune Diseases of the Nervous System (1) · Brain Injuries (1) · Cardiovascular Diseases (1) · Cerebrovascular Disorders (1) · Craniocerebral Trauma (1) · Dementia (1) · Demyelinating Autoimmune Diseases, CNS (1) · Demyelinating Diseases (1)
dextromethorphan - quinidine combination (3) · Dextromethorphan (1) · Quinidine (1)
Avanir Pharmaceuticals (2) · St. Joseph's Hospital and Medical Center, Phoenix (1)
United States (3) · Argentina (1) · Brazil (1)
Adrian Hepner, M.D. (1) · Jiong Shi, MD, PhD (1)