87 completed, 14 unknown, 4 active not recruiting, 4 not yet recruiting. 30 Phase 3, 25 Phase 4, 18 Not applicable, 14 Phase 2, 13 Phase 1.
Follow Postmenopausal Osteoporosis: new trials by email Literature Review of Postmenopausal Osteoporosis trials Research Report on Postmenopausal Osteoporosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Romosozumab and Denosumab Combination Therapy for Osteoporosis Romosozumab, Romosozumab and Denosumab - Postmenopausal Osteoporosis | Phase 4 | Not yet recruiting | Massachusetts General Hospital | 100 | 2027-01-01 | 2026-11-03 |
| Feasibility of a Novel Resistance Exercise in Individuals With Osteoporosis Exercise training - Osteopenia, Osteoporosis | Not applicable | Withdrawn | University of Alabama at Birmingham | 2026-12-01 | 2026-07-01 | |
| Study of TST002 Injection in Postmenopausal Women With Osteoporosis or Low Bone Mass Denosumab, Placebo - Postmenopausal Osteoporosis, Low Bone Mass | Phase 2 | Not yet recruiting | Transcenta Therapeutics (Hangzhou) Co., Ltd. | 110 | 2026-10-31 | 2026-09-11 |
| Effects of Sensorimotor Balance Training vs Digitally Augmented Core Stabilization in Women With Osteoporosis Sensorimotor-Based Balance Training, Digitally Augmented Core Stabilization - Postmenopausal Osteoporosis | Not applicable | Not yet recruiting | Riphah International University | 40 | 2026-09-01 | 2026-10-15 |
| The Comparison of Ibandronate and Zoledronic Acid After Denosumab Discontinuation Ibandronate IV, Zoledronic acid IV - Postmenopausal Osteoporosis, Postmenopausal Osteopenia | Phase 4 | Recruiting | National Taiwan University Hospital | 52 | 2026-08-20 | 2026-08-25 |
| Blackcurrants Modify Gut Microbiota and Reduce Osteoporosis Risk in Postmenopausal Females Blackcurrant (BC) extract, Placebo - Postmenopausal Osteoporosis, Gut Microbiome | Phase 1 | Recruiting | University of Connecticut | 159 | 2026-07-01 | 2026-07-23 |
| Can Serum Lumican Level Identify a Hidden Fragility Phenotype Beyond Bone Mineral Density in Postmenopausal Women? Osteoporosis, Postmenopausal Osteoporosis | Recruiting | Kanuni Sultan Suleyman Training and Research Hospital | 98 | 2026-05-15 | 2026-06-30 | |
| AGE Burden and Response to Antiresorptive Therapy in Osteoporosis Osteoporosis, Postmenopausal Osteoporosis | Not yet recruiting | Bursa City Hospital | 240 | 2026-01-15 | 2026-01-09 | |
| StrAtegies For Zoledronic Acid Post-dEnosumab Discontinuation in Postmenopausal oSTeoporosis a second infusion of ZOL when crosslaps levels reach 300 pg/mL, a rescue second infusion at month-12 (standard traitment) - Postmenopausal Osteoporosis | Phase 4 | Recruiting | University Hospital, Toulouse | 200 | 2025-10-02 | 2025-12-31 |
| The Impact of Osteosarcopenia on Falls, Kinesiophobia, and Quality of Life in Postmenopausal Women Dual-energy x-ray absorptiometer - Osteosarcopenia, Sarcopenia | Active not recruiting | Ayşe Ukbe Baykut | 109 | 2025-01-02 | 2026-11-04 | |
| A Trial Evaluating Efficacy of AGA2118 in PostMenopausal Women wIth Low Bone MasS (ARTEMIS) AGA2118, Placebo - Postmenopausal Osteoporosis | Phase 2 | Active not recruiting | Angitia Biopharmaceuticals | 379 | 2024-10-31 | 2026-02-10 |
| Treatment Exercises With Core Stability and Dynamic Resistance Exercise for Postmenopausal Women With Osteoporosis Alendronate, treatment exercises - Postmenopausal Osteoporosis | Not applicable | Completed | Cairo University | 60 | 2024-02-01 | 2024-06-26 |
| A Study of Romosozumab (EVENITY®) in Postmenopausal Women in India With Osteoporosis at a High Risk of Fracture. Romosozumab - Postmenopausal Osteoporosis | Phase 4 | Completed | Amgen | 100 | 2023-10-30 | 2026-10-21 |
| Eldecalcitol and Calcitriol in Postmenopausal Women With Low Bone Mineral Density or Mild Osteoporosis Eldecalcitol capsules, Calcitriol capsules - Low Bone Mineral Density, Postmenopausal Osteoporosis | Phase 4 | Unknown | Shanghai Jiao Tong University Affiliated Sixth People's Hospital | 300 | 2023-09-27 | 2024-05-16 |
| Efficacy and Safety of Actonel® After Denosumab Discontinuation in Postmenopausal Osteoporosis Women Risedronate Sodium 35 MG [Actonel], Calcium Vitamin D combination - Postmenopausal Osteoporosis | Phase 4 | Completed | Dong-A ST Co., Ltd. | 149 | 2023-01-03 | 2025-08-24 |
| Progressive Strength and Balance Exercise for Fall Prevention in Postmenopausal Women With Osteoporosis Supervised Progressive Strength and Balance Exercise Program, Home-Based Conventional Exercise Program - Postmenopausal Osteoporosis, Accidental Falls, Aged, Exercise Movement Techniques | Not applicable | Completed | Instituto Nacional de Rehabilitacion | 46 | 2023-01-01 | 2026-07-06 |
| Efficacy and Safety of Minodronate in Patients With Low Back Pain Minodronate, Alendronate - Postmenopausal Osteoporosis | Phase 4 | Unknown | Peking University Third Hospital | 72 | 2023-01-01 | 2022-12-09 |
| Impact of Ultraviolet Radiation on Bone Density and Muscle Strength in Postmenopausal Women Ultraviolet Radiation, Aerobic exercise, Vitamin D supplementation - Postmenopausal Osteoporosis | Not applicable | Completed | Cairo University | 70 | 2022-12-30 | 2024-01-12 |
| Post-Marketing Drug Intensive Monitoring Surveillance of EDIROL in Patients With Postmenopausal Osteoporosis Eldecalcitol soft capsules - Postmenopausal Osteoporosis | Unknown | Chugai Pharmaceutical | 1000 | 2022-08-01 | 2022-06-27 | |
| A Phase 3 Study to Compare Biosimilar Denosumab With Prolia® ENZ215, Prolia - Postmenopausal Osteoporosis | Phase 3 | Completed | Enzene Biosciences Ltd. | 504 | 2022-07-04 | 2026-02-10 |
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Osteoporosis, Postmenopausal (117) · Osteoporosis (43) · Bone Diseases, Metabolic (18) · Bone Diseases (3) · Fractures, Bone (3) · Spinal Fractures (3) · Bone Resorption (2) · Hyperparathyroidism (2) · Motor Activity (2) · Musculoskeletal Diseases (2) · Sarcopenia (2) · Sclerosteosis (2) · Vitamin D Deficiency (2) · Acute-Phase Reaction (1) · Cardiovascular Diseases (1)
Metabolic Diseases (117) · Nutritional and Metabolic Diseases (117) · Musculoskeletal Diseases (115) · Bone Diseases (114) · Bone Diseases, Metabolic (99) · Osteoporosis (74) · Pathological Conditions, Signs and Symptoms (6) · Wounds and Injuries (6) · Signs and Symptoms (4) · Back Injuries (3) · Behavior (3) · Endocrine System Diseases (3) · Fractures, Bone (3) · Neurologic Manifestations (3) · Spinal Injuries (3)
Denosumab (27) · Alendronate (14) · Teriparatide (13) · Ibandronic Acid (10) · Risedronic Acid (8) · romosozumab (8) · Zoledronic Acid (6) · Cholecalciferol (5) · Calcium Carbonate (4) · Vitamin D (3) · Calcium (2) · Exercise (2) · QL1206 (2) · Raloxifene Hydrochloride (2) · abaloparatide (2)
Amgen (15) · Hoffmann-La Roche (9) · Massachusetts General Hospital (6) · Warner Chilcott (5) · Radius Health, Inc. (4) · Eli Lilly and Company (3) · Merck Sharp & Dohme LLC (3) · Novartis (3) · Organon and Co (3) · Peking University Third Hospital (3) · Riphah International University (3) · Cairo University (2) · Fujian Academy of Traditional Chinese Medicine (2) · Hospital Regional 1o de Octubre (2) · Second Affiliated Hospital of Soochow University (2)
United States (31) · China (17) · Poland (17) · Czechia (10) · Denmark (10) · Belgium (9) · Hungary (9) · Spain (9) · Argentina (8) · Canada (8) · Estonia (7) · Greece (7) · Germany (6) · Brazil (5) · Mexico (5)
Benjamin Leder, MD (3) · Athanasios D Anastasilakis, MD, PhD (2) · Chunli Song, M.D.; Ph. D. (2) · Patricia Loranca-Moreno, M.D., M.Sc. (2) · Polyzois Makras, MD, PhD (2) · Weibo Xia (2) · Ahmed M Maged (1) · Ana Balske, MD, PhD (1) · Antonio Cano, MD (1)
PMID 21289258, PMID 31411768, PMID 31674644, PMID 31776637, PMID 32658264, PMID 36588166, PMID 11138687, PMID 1421796, PMID 16557117, PMID 16999712, PMID 18381571, PMID 18539106, PMID 19055791, PMID 19345291, PMID 19584192, PMID 19594293, PMID 19671655, PMID 20003299, PMID 20533525, PMID 20839291, PMID 21111078, PMID 21605732, PMID 21947137, PMID 22152181, PMID 22289659, PMID 23234813, PMID 23719683, PMID 23812464, PMID 24382002, PMID 24771986, PMID 24909074, PMID 25179289, PMID 25933031, PMID 26556736, PMID 26744141, PMID 26864614, PMID 27533157, PMID 27612281, PMID 27826127, PMID 28160873, PMID 28240371, PMID 28546097, PMID 29105841, PMID 29129436, PMID 29329484, PMID 29800372, PMID 30205020, PMID 30659410, PMID 31433518, PMID 31447409
2005 (1), 2008 (1), 2009 (1), 2025 (1), P50AR044855 (1), R01AR073191 (1), R01NR007743 (1)