13 completed, 4 recruiting, 3 unknown, 2 terminated. 5 Phase 4, 4 Not applicable, 2 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 5 | Completed 2, Unknown 2, Terminated 1 |
| Not applicable | 4 | Recruiting 3, Withdrawn 1 |
| Phase 2 | 2 | Terminated 1, Withdrawn 1 |
| Phase 3 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
Follow Polyneuropathy: new trials by email Literature Review of Polyneuropathy trials Research Report on Polyneuropathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Resistance Exercises in Hereditary Sensory-Motor Neuropathy (Charcot-Marie-Tooth Disease) Progressive Resistance Exercise Training - Polyneuropathy, Charcot Marie Tooth Disease (CMT) | Not applicable | Recruiting | Universidad de La Frontera | 22 | 2025-09-20 | 2025-09-23 |
| Turkish Validation and Reliability of the John Hopkins In-Room Independence Scale In-room independence assessment - Independence, Hemiplegia | Completed | Sisli Hamidiye Etfal Training and Research Hospital | 100 | 2025-09-01 | 2026-02-27 | |
| A New Cancer Rehabilitation Process for Chemotherapy-Induced Foot Neuropathy Using Orthopedic Devices Silicone orthosis, Standard Treatment - Polyneuropathy, Breast Cancer | Not applicable | Recruiting | Vastra Gotaland Region | 40 | 2024-12-01 | 2025-04-01 |
| Prodromal Model of Parkinson's Disease Confined to The Peripheral Nervous System Polyneuropathy, Alpha-Synucleinopathy | Enrolling by invitation | University of Aarhus | 100 | 2024-05-13 | 2025-01-08 | |
| Hereditary Transthyretin Amyloidosis Polyneuropathy in Patients With Carpal Tunnel Syndrome in Russia Hereditary Transthyretin Amyloidosis, Carpal Tunnel Syndrome | Completed | AstraZeneca | 721 | 2023-12-29 | 2026-06-04 | |
| Prevalence of Wild-type TTR Cardiac Amyloidosis in Patients With Polyneuropathy of Unknown Cause. ECG + echocardiography, Answering questionnaires - Polyneuropathy, Amyloidosis | Not applicable | Recruiting | Universitair Ziekenhuis Brussel | 150 | 2023-07-28 | 2025-07-22 |
| Retrospective Study Collecting Neurological Follow-up of Hereditary Transthyretin Amyloidosis (ATTRv) Patients Included in B3461028 and B3461045. Tafamidis - Hereditary Transthyretin Amyloidosis (ATTRv), Polyneuropathy | Completed | Pfizer | 5 | 2022-10-24 | 2024-05-13 | |
| Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance Program Hereditary Transthyretin-mediated (hATTR) Amyloidosis, Polyneuropathy | Recruiting | Alnylam Pharmaceuticals | 10 | 2020-08-01 | 2026-10-08 | |
| A Multicenter Observational Study to Evaluate the Effectiveness of Patisiran in Patients With Polyneuropathy of ATTRv Amyloidosis With a V122I or T60A Mutation Patisiran - Hereditary Transthyretin-mediated (ATTRv) Amyloidosis, Polyneuropathy | Completed | Alnylam Pharmaceuticals | 67 | 2019-12-18 | 2022-06-06 | |
| Early Diagnosis of TTR Amyloidosis by Use of Molecular Biology Polyneuropathy, Diagnosis | Completed | Assistance Publique - Hôpitaux de Paris | 560 | 2017-03-17 | 2022-12-08 | |
| The Influence of Sensory Phenotype on the Risk of Developing Neuropathic Pain QST, Questionnaires - Neuropathic Pain, Polyneuropathy | Unknown | University of Kiel | 1500 | 2016-04-01 | 2016-01-28 | |
| Impact of Human Blood Serum From Critically Ill Patients on Human Colon Neuronal Networks. Critical Illness, Multiple Organ Failure | Completed | University of Rostock | 61 | 2016-03-01 | 2019-04-18 | |
| Neuromuscular Electrical Stimulation in the Critically Ill Gymna Belgium, DUO 400 (Neuromuscular electrical stimulation) - Polyneuropathy | Not applicable | Withdrawn | Brugmann University Hospital | 2015-10-01 | 2018-05-31 | |
| Neurological Outcome in Surgical and Non-surgical Septic Patients Critical-Illness, Polyneuropathy | Completed | University of Rostock | 32 | 2012-11-01 | 2017-04-20 | |
| Muscular Electrostimulation of the Sedated and Mechanically Ventilated Critically Ill Patient. Analysis of the Effect on Acquired Muscular Weakness and Its Clinical Consequences. Muscular electrostimulation and percutaneus muscular biopsy. - Polyneuropathy | Phase 4 | Unknown | Hospital Universitario La Fe | 40 | 2012-10-01 | 2014-01-10 |
| Evaluate The Efficacy and Safety Of Pregabalin In Prevention, Reduction of Oxaliplatin-Induced Painful Neuropathy Pregabalin, Oxaliplatin, Placebo , Oxaliplatin - Pain, Neuropathic Pain | Phase 3 | Completed | University of Sao Paulo | 200 | 2011-08-01 | 2017-05-09 |
| Efficacy of Etoricoxib on Peripheral Hyperalgesia Etoricoxib, placebo - Causalgia, Polyneuropathy | Phase 2 | Terminated | Ruhr University of Bochum | 9 | 2011-02-01 | 2012-08-24 |
| Oxcarbazepine for the Treatment of Chronic Peripheral Neuropathic Pain Oxcarbazepine - Polyneuropathy, Peripheral Nerve Injury | Phase 4 | Completed | Søren H. Sindrup | 117 | 2011-02-01 | 2014-05-05 |
| Patients With Chemotherapy-induced Polyneuropathy Are Treated With an Integrated Program Including Massage, Mobilization in Posture and Transport Layers, Physical Exercises or With Whole-body Vibration Platform Training Polyneuropathy | Completed | University of Ulm | 122 | 2010-06-01 | 2016-07-29 | |
| Imipramine and Pregabalin Combination in Painful Polyneuropathy Imipramine, Pregabalin, Imipramine, pregabalin - Polyneuropathy | Phase 4 | Unknown | Odense University Hospital | 75 | 2010-02-01 | 2010-01-13 |
Showing 20 of 25. Sign in to see all of them.
Polyneuropathies (25) · Amyloidosis (4) · Neuralgia (4) · Amyloidosis, Hereditary, Transthyretin-Related (3) · Peripheral Nerve Injuries (3) · Amyloid Neuropathies, Familial (2) · Amyloidosis, Familial (2) · Critical Illness (2) · Muscular Diseases (2) · Neuralgia, Postherpetic (2) · Pain (2) · Parkinson Disease (2) · Peripheral Nervous System Diseases (2) · Acquired Immunodeficiency Syndrome (1) · Amyloid Neuropathies (1)
Nervous System Diseases (24) · Neuromuscular Diseases (24) · Peripheral Nervous System Diseases (23) · Pathological Conditions, Signs and Symptoms (11) · Neurologic Manifestations (8) · Signs and Symptoms (8) · Nutritional and Metabolic Diseases (5) · Metabolic Diseases (4) · Neurodegenerative Diseases (4) · Pain (4) · Pathologic Processes (4) · Proteostasis Deficiencies (4) · Wounds and Injuries (4) · Central Nervous System Diseases (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3)
Pregabalin (2) · Cilostazol (1) · Echocardiography (1) · Electrocardiography (1) · Etoricoxib (1) · Imipramine (1) · Interactive Ventilatory Support (1) · Methadone (1) · Oxaliplatin (1) · Oxcarbazepine (1) · Ranolazine (1) · Rituximab (1) · Surveys and Questionnaires (1) · nabiximols (1) · patisiran (1)
Alnylam Pharmaceuticals (2) · Assistance Publique - Hôpitaux de Paris (2) · University of Rostock (2) · AstraZeneca (1) · Brugmann University Hospital (1) · Gilead Sciences (1) · Hospital Universitario La Fe (1) · Insel Gruppe AG, University Hospital Bern (1) · Odense University Hospital (1) · Otsuka Pharmaceutical, Inc., Philippines (1) · Pfizer (1) · Ruhr University of Bochum (1) · Sisli Hamidiye Etfal Training and Research Hospital (1) · Søren H. Sindrup (1) · Universidad de La Frontera (1)
Germany (4) · United States (4) · Denmark (3) · France (3) · Spain (3) · Belgium (2) · Brazil (1) · Chile (1) · Italy (1) · Netherlands (1) · Philippines (1) · Portugal (1) · Russia (1) · Sweden (1) · Switzerland (1)
Astrid J. Terkelsen, MD, DrMedSc, PhD, Professor (1) · Banu Kuran, Professor (1) · Christoph Maier, Dr.med (1) · Craig Walker, MD (1) · Daniel C de Andrade, MD, PhD (1) · David B. Clifford, MD (1) · Jacques Devriendt, MD (1) · Jakob V. Holbech, MD (1) · Lukas Brander, MD (1) · Martin Sauer, MD (1) · Raymond Rosales, MD, PhD (1)
PMID 22048718, PMID 28194306, PMID 28652279, PMID 29058589, PMID 38982001
2009 (2), U01NS032228 (1)