99 completed, 63 unknown, 30 recruiting, 17 not yet recruiting. 232 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 232 | Completed 99, Unknown 63, Recruiting 30, Not yet recruiting 17, Terminated 13, Active not recruiting 6, Withdrawn 3, Enrolling by invitation 1 |
Follow Pleural Diseases: new trials by email Literature Review of Pleural Diseases trials Research Report on Pleural Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Iodine Starch Test Use in Pleuroperitoneal Leak Iodine tincture - Peritoneal Dialysis, Peritoneal Dialysis (PD) | Not applicable | Not yet recruiting | Nottingham University Hospitals NHS Trust | 30 | 2026-12-01 | 2026-10-26 |
| Evaluating Antibiotic Course Upon Adequate Treatment of Empyema shortened antibiotic course, Standard medical treatment - Pleural Empyema | Not applicable | Not yet recruiting | University of Arizona | 50 | 2026-11-16 | 2026-10-07 |
| Safety and Feasibility of Medical Thoracoscopy Using Single-use Flexible Bronchoscope Versus SemiRigid Pleuroscope in Pleural Effusion Single-Use Flexible Bronchoscope, Semi-Rigid Pleuroscope - Malignant Pleural Effusions (Mpe), Medical Thoracoscopy | Not applicable | Recruiting | National University of Malaysia | 36 | 2026-08-20 | 2026-09-11 |
| Dual-function Semirigid Thoracoscopy Versus Rigid Thoracoscopy for the Diagnosis of Pleural Disease Dual-function semi-rigid thoracoscopy, Rigid thoracoscopy - Pleural Effusion Disorder | Not applicable | Not yet recruiting | China-Japan Friendship Hospital | 92 | 2026-08-01 | 2026-06-22 |
| Xuan Yin Ning Plus Bevacizumab for Malignant Pleural Effusion Treatment with Xuanyin Ning Formula combined with intrapleural injection of bevacizumab via chest tube drainage, Placebo granules plus chest tube drainage and intrapleural bevacizumab injection - Malignant Pleural Effusions (Mpe) | Not applicable | Not yet recruiting | Shanghai Chest Hospital | 308 | 2026-06-01 | 2026-07-01 |
| Suction vs Underwater Seal for HemoPneumoThoraX Trial Suction, Water Seal - Hemothorax; Traumatic, Hemopneumothorax; Traumatic | Not applicable | Recruiting | Vanderbilt University Medical Center | 150 | 2026-04-14 | 2026-06-02 |
| AI-Assisted Chest X-Ray for Misplaced Endotracheal and Nasogastric Tubes and Pneumothorax in Emergency and Critical Care Settings AI-assisted model - Endotracheal Tube, Nasogastric Tube | Not applicable | Not yet recruiting | National Taiwan University Hospital | 10900 | 2026-04-01 | 2026-03-17 |
| Ultrasounic Elastography-guided Pleural Biopsy Followed by As-needed Medical Thoracoscopic Pleural Biopsy Versus Immediate Medical Thoracoscopic Pleural Biopsy for the Diagnosis of Pleural Effusion Ultrasoinc elastography-guided pleural biopsy followed by as-needed medical thoracoscopic pleural biopsy, Semi-rigid thoracoscopic pleural biopsy - Pleural Effusion Disorder | Not applicable | Not yet recruiting | China-Japan Friendship Hospital | 420 | 2026-04-01 | 2026-02-19 |
| Evaluating the Use of an App in Pleural Disease: Algorithm-supported Clinical Decision Making Versus Usual Care Clinical decision-making support tool, Usual care - Pleural Diseases, Pneumothorax Spontaneous Primary | Not applicable | Enrolling by invitation | Zealand University Hospital | 828 | 2026-04-01 | 2026-06-04 |
| Olive Oil Before Lung Cancer Surgery to Prevent Chylothorax Extra-Virgin Olive Oil - Lung Cancer, Chylothorax | Not applicable | Recruiting | Fudan University | 1036 | 2026-03-15 | 2026-09-08 |
| Safety And Recovery Of Tubeless Strategy In Uniportal VATS Wedge Resection Conventional Chest Tube Drainage, Single Intraoperative Aspiration Tubeless, Double Intraoperative Aspiration Tubeless - Pulmonary Nodule, Pneumothorax | Not applicable | Not yet recruiting | The First Affiliated Hospital of Guangzhou Medical University | 300 | 2026-02-28 | 2026-02-09 |
| DRAIN: DRainage in Acute Decompensated Heart faIlure With Pleural effusioNs Thoracentesis - Congestive Heart Failure(CHF), Pleural Effusion Due to Congestive Heart Failure | Not applicable | Recruiting | Albany Medical College | 216 | 2026-02-15 | 2026-04-30 |
| Comparison of Talc Slurry Versus Talc Insufflation: A Study on Effectiveness, Safety, and Hospital Outcomes in Pleurodesis Pleurodesis, pleurodesis - Pneumothorax Spontaneous Primary, Pneumothorax Spontaneous Secondary | Not applicable | Not yet recruiting | University of Health Sciences Lahore | 160 | 2026-02-01 | 2026-01-06 |
| Pleurodesis in Small-bore Chest Tube 14 Fr chest tube, 12 Fr chest tube, 8 Fr chest tube - Pleural Effusion, Malignant | Not applicable | Not yet recruiting | The University of Hong Kong | 60 | 2026-02-01 | 2025-12-24 |
| Evaluation of the Efficacy of Diagnostic Support Algorithms in Chest X-rays- LuAna Trial App LuAna - Consolidation, Lung Injury | Not applicable | Recruiting | Hospital Israelita Albert Einstein | 2400 | 2026-01-05 | 2026-09-16 |
| Conservative Management in Primary Spontaneous Pneumothorax: a Multicenter Randomized Non-inferiority Study Conservative management (active observation), Chest tube drainage - Primary Spontaneous Pneumothorax (PSP), Conservative Management (Active Observation) | Not applicable | Not yet recruiting | Corporacion Parc Tauli | 436 | 2026-01-01 | 2026-01-12 |
| Comparison of Chest Tube Wound Closure: Comparison Between Purse String Method and Plug Method. Purse string suture closure, Plug method closure - Pneumothorax, Hemothorax | Not applicable | Not yet recruiting | Pakistan Institute of Medical Sciences | 246 | 2026-01-01 | 2026-01-06 |
| Impact of Ambulatory Management for Primary Spontaneous Pneumothorax in the Emergency Department on Quality of Life Ambulatory management, Standard Care - Primary Spontaneous Pneumothorax, Quality of Life | Not applicable | Not yet recruiting | University Hospital, Strasbourg, France | 386 | 2025-12-01 | 2025-11-26 |
| Study of the Benefits of Virtual Reality Headsets for Reducing Anxiety in Patients Treated for Pleural Effusion or Pneumothorax Using Small-bore Chest Drainage Tubes Drainage with Headset Hypno VR - Pneumothorax, Pleural Effusion | Not applicable | Active not recruiting | Centre Hospitalier Universitaire de Nice | 38 | 2025-11-27 | 2025-12-31 |
| Effect of Bubble Positive Expiratory Pressure and Segmental Breathing Versus Incentive Spirometry in Pleural Effusion Bubble PEP, Incentive Spirometery - Pleural Effusion | Not applicable | Recruiting | Riphah International University | 40 | 2025-10-28 | 2025-11-25 |
Showing 20 of 232. Sign in to see all of them.
Pleural Effusion (99) · Pneumothorax (85) · Pleural Effusion, Malignant (38) · Hemothorax (15) · Empyema, Pleural (13) · Lung Neoplasms (10) · Pulmonary Atelectasis (10) · Pneumonia (9) · Empyema (8) · Heart Failure (6) · Pulmonary Edema (6) · Hydrothorax (5) · Mesothelioma (5) · Neoplasms (5)
Respiratory Tract Diseases (232) · Pathological Conditions, Signs and Symptoms (69) · Pathologic Processes (56) · Neoplasms (48) · Neoplasms by Site (46) · Respiratory Tract Neoplasms (45) · Thoracic Neoplasms (45) · Pleural Neoplasms (38) · Lung Diseases (36) · Infections (31) · Pleural Effusion (28) · Respiratory Tract Infections (26) · Cardiovascular Diseases (18) · Signs and Symptoms (18)
Chest Tubes (5) · Thoracentesis (5) · Drainage (4) · Pleurodesis (3) · Thoracic Surgery, Video-Assisted (3) · Ultrasonography (3) · Acetaminophen (2) · Conservative Treatment (2) · Constriction (2) · Continuous Positive Airway Pressure (2) · Control Groups (2) · Therapeutics (2) · Thoracoscopy (2) · Bed Rest (1) · Blood Specimen Collection (1)
Assiut University (12) · China-Japan Friendship Hospital (6) · Post Graduate Institute of Medical Education and Research, Chandigarh (5) · National Taiwan University Hospital (4) · Vanderbilt University Medical Center (4) · Ain Shams University (3) · Naestved Hospital (3) · National University of Malaysia (3) · Universidade Cidade de Sao Paulo (3) · University of Health Sciences Lahore (3) · Aarhus University Hospital Skejby (2) · Ajou University School of Medicine (2) · Alexandria University (2) · Beth Israel Deaconess Medical Center (2) · Brigham and Women's Hospital (2)
United States (38) · Egypt (20) · China (15) · France (14) · Canada (12) · Denmark (12) · United Kingdom (11) · Italy (9) · Pakistan (8) · Taiwan (8) · India (7) · Israel (6) · Brazil (5) · South Korea (4) · Spain (4)
Adriana C Lunardi, PhD (2) · Deborah L O'Connor, PhD RD (2) · Idit Matot, MD (2) · Jennifer Russell, MD (2) · Mohamed Faisal Abdul Hamid, MBBS (IIUM) (2) · Patrick Sorkine, MD (2) · Abdelfatah E Abugabal (1) · Abdelrahman Ahmed Mohamed, Teaching assistant (1) · Adel S Bediwy, Professor (1) · Adriana Lunardi, PhD (1) · Alexander C Chen, MD (1) · Amal A Mohamed (1) · Ana L. Boechat, MD (1) · Andrew W Kirkpatrick, MD (1)
PMID 11451810, PMID 24375295, PMID 10727592, PMID 10899243, PMID 11171742, PMID 11991872, PMID 12603352, PMID 15454805, PMID 15753638, PMID 16135163, PMID 16307931, PMID 17161082, PMID 17167009, PMID 17253510, PMID 17650692, PMID 17943347, PMID 18053373, PMID 18216051, PMID 18422864, PMID 19651381, PMID 20154079, PMID 20304453, PMID 20464170, PMID 20646242, PMID 20685739, PMID 20696688, PMID 20696690, PMID 20736395, PMID 21307755, PMID 21633576, PMID 22071915, PMID 22205619, PMID 22310111, PMID 22327984, PMID 22925840, PMID 22929504, PMID 23188235, PMID 23418922, PMID 23433600, PMID 23928984, PMID 24106326, PMID 25367064, PMID 25377015, PMID 25387438, PMID 25744852, PMID 25777978, PMID 25788749, PMID 25861647, PMID 25874452, PMID 25919389
P30AG021342 (1), P30CA006927 (1), P30CA068485 (1)