3 not yet recruiting, 1 active not recruiting. 4 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 4 | Not yet recruiting 3, Active not recruiting 1 |
Follow Perimenopause: new trials by email Literature Review of Perimenopause trials Research Report on Perimenopause
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Migraine Menopause Study Eptinezumab 100 mg or Eptinezumab 300 mg administered intravenously in 100 mL saline solution, Placebo Normal Saline (NS) - Migraine, Menopausal | Phase 4 | Not yet recruiting | Alberta Neurologic Centre | 120 | 2027-02-01 | 2026-11-04 |
| Hormone thERapy Effects on BRAin-HEART Health During the Menopausal Transition Transdermal estradiol, Standard of care - non hormonal - Menopause, Perimenopause | Phase 4 | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 100 | 2026-11-01 | 2026-07-29 |
| Vaginal Estradiol vs Moisturizer to Improve Postmenopausal Vaginal Aging Symptoms and the Microbiome in Women Living With HIV Vaginal estradiol tablets, Vaginal moisturizer - Menopausal Complaints, Vaginal Atrophy | Phase 4 | Not yet recruiting | Albert Einstein College of Medicine | 62 | 2026-09-01 | 2026-07-28 |
| Impact of Estradiol on Endothelial Function in Peri-Menopausal Women Estradiol (mylan or vivelle dot patch), Placebo - Perimenopause, Vasodilation | Phase 4 | Active not recruiting | University of Delaware | 80 | 2020-10-01 | 2026-04-29 |
Acquired Immunodeficiency Syndrome (1) · Aging, Premature (1) · Aneurysm (1) · Atrophic Vaginitis (1) · Dysbiosis (1) · HIV Infections (1) · Migraine Disorders (1) · Vaginitis (1)
Blood-Borne Infections (1) · Brain Diseases (1) · Cardiovascular Diseases (1) · Central Nervous System Diseases (1) · Communicable Diseases (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Genital Diseases (1) · Genital Diseases, Female (1) · Headache Disorders (1) · Headache Disorders, Primary (1) · Immune System Diseases (1) · Immunologic Deficiency Syndromes (1) · Infections (1) · Lentivirus Infections (1)
Estradiol (3) · Gabapentin (1) · Gels (1) · Replens (1) · Saline Solution (1) · Selective Serotonin Reuptake Inhibitors (1) · eptinezumab (1) · fezolinetant (1) · oxybutynin (1)
Albert Einstein College of Medicine (1) · Alberta Neurologic Centre (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · University of Delaware (1)
United States (2)
Kerry J Murphy, MD (1) · Lisa C Rosenegger, MD, DPhil, FRCPC (1)
R01AG102277 (1), R01HL146558 (1)