11 completed, 3 unknown, 2 active not recruiting, 2 not yet recruiting. 11 Not applicable, 4 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 5, Not yet recruiting 2, Unknown 2, Terminated 1, Withdrawn 1 |
| Phase 4 | 4 | Completed 2, Recruiting 1, Terminated 1 |
| Phase 2 | 1 | Active not recruiting 1 |
Follow Perforated Appendicitis: new trials by email Literature Review of Perforated Appendicitis trials Research Report on Perforated Appendicitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Perforated Appendicitis and Postoperative Antibiotics Pilot Trial Postoperative antibiotico-prophylaxis, No postoperative antibiotics - Perforated Appendicitis | Not applicable | Not yet recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 100 | 2027-01-01 | 2026-09-17 |
| Comparative Study Between Laparoscopic and Open Appendectomy of Complicated Appendicitis Laparoscopic Appendectomy, Open Appendectomy - Appendicitis, Perforated Appendicitis | Not applicable | Not yet recruiting | Assiut University | 100 | 2026-11-01 | 2026-10-16 |
| APPI-Cost Trial for Perforated Appendicitis PVI, Usual Care - Perforated Appendicitis | Phase 4 | Recruiting | The University of Texas Health Science Center, Houston | 346 | 2025-04-07 | 2025-12-11 |
| Effect of Intraperitoneal Drain Placement on Postoperative Outcomes Following Laparoscopic Appendectomy in Adult Patients With Perforated Appendicitis No abdominal drain is placed - Perforated Appendicitis | Active not recruiting | The Affiliated Hospital of Qingdao University | 500 | 2024-06-01 | 2025-04-15 | |
| Surgical Site Infection in Perforated Appendicitis After Peritoneal Lavage With Super-oxidised Solution Superoxidized Water, Normal Saline - Perforated Appendicitis | Not applicable | Completed | Hospital Queen Elizabeth, Malaysia | 102 | 2020-09-09 | 2022-05-25 |
| Frequency of Perforated Appendicitis in Times of COVID-19 appendectomy - Perforated Appendicitis, Covid19 | Completed | University Hospital Tuebingen | 143 | 2020-03-16 | 2020-07-15 | |
| The Management of Perforated Acute Appendicitis in Adult and Pediatric Populations Appendectomy, Observation - Perforated Appendicitis | Not applicable | Unknown | Marshall University | 100 | 2020-02-20 | 2023-04-04 |
| Use of Antibiotic Irrigation to Decrease Wound Infections in Pediatric Perforated Appendicitis antibiotic rinse with suction, suction only - Perforated Appendicitis | Phase 2 | Active not recruiting | Prisma Health-Upstate | 200 | 2019-07-25 | 2026-01-27 |
| Antibiotic Duration in Post-appendectomy Abscess ampicillin/clavulanate - Complicated Appendicitis, Perforated Appendicitis | Phase 4 | Terminated | Phoenix Children's Hospital | 7 | 2019-05-01 | 2024-03-08 |
| Evaluation the Role of Laparoscopic Management of Perforated Appendicitis Laparoscopic management of perforated appendicitis - Perforated Appendicitis | Not applicable | Unknown | Assiut University | 30 | 2017-09-15 | 2017-08-30 |
| Optimal Care of Complicated Appendicitis Early Appendectomy, Interval Appendectomy, Antibiotics - Appendicitis, Perforated Appendicitis | Phase 4 | Completed | University of Michigan | 40 | 2017-06-29 | 2023-11-28 |
| Two Different Antibiotics Versus One Antibiotic for Pediatric Perforated Appendicitis Piperacillin, Tazobactam Drug Combination - Perforated Appendicitis, Postoperative Infection | Phase 4 | Completed | Phoenix Children's Hospital | 162 | 2017-05-22 | 2024-01-12 |
| The Impact of IV Acetaminophen on Pain After Appendectomy for Perforated Appendicitis IV tylenol, No IV tylenol, Ketorolac - Perforated Appendicitis | Not applicable | Completed | Children's Mercy Hospital Kansas City | 90 | 2014-06-01 | 2021-01-12 |
| Role of Intravenous Versus Home Oral Antibiotics in Perforated Appendicitis home intravenous ertapenem, home oral amoxicillin-clavulanate, peripheral inserted central Catheter - Perforated Appendicitis | Not applicable | Completed | Wake Forest University Health Sciences | 82 | 2011-01-01 | 2022-05-17 |
| Irrigation Versus No Irrigation for Perforated Appendicitis Irrigation, No Irrigation - Perforated Appendicitis | Not applicable | Completed | Children's Mercy Hospital Kansas City | 220 | 2008-12-01 | 2012-08-01 |
| Diagnostic Value of Hyperbilirubinaemia as a Predictive Factor for Appendiceal Perforation in Acute Appendicitis Perforated Appendicitis | Completed | Ruhr University of Bochum | 538 | 2008-05-01 | 2012-10-16 | |
| Study on Laparoscopic Operation for Perforated Appendicitis Laparoscopic appendectomy, Open appendectomy - Perforated Appendicitis | Unknown | Far Eastern Memorial Hospital | 60 | 2008-05-01 | 2009-02-09 | |
| Initial Versus Delayed Operation for Treatment of Complicated Appendicitis In Children Initial appendectomy, Interval appendectomy - Perforated Appendicitis | Not applicable | Terminated | University of Michigan | 23 | 2008-05-01 | 2016-12-19 |
| Hyperbilirubinemia in Acute Appendicitis as a Predictor of Perforation Laboratory Test - Perforated Appendicitis | Completed | Cirujanos la Serena | 132 | 2007-10-01 | 2009-11-10 | |
| Intravenous Versus Intravenous/Oral Antibiotics for Perforated Appendicitis 5 days of IV antibiotics (ceftriaxone and metronidazole), Home with oral antibiotics when eating (ampicillin/clavulanic acid) - Perforated Appendicitis | Not applicable | Completed | Children's Mercy Hospital Kansas City | 102 | 2007-03-01 | 2021-02-21 |
Showing 20 of 22. Sign in to see all of them.
Appendicitis (22) · Abdominal Abscess (2) · Surgical Wound Infection (2) · Abscess (1) · COVID-19 (1) · Hyperbilirubinemia (1) · Pain (1) · Peritonitis (1)
Cecal Diseases (22) · Digestive System Diseases (22) · Gastroenteritis (22) · Gastrointestinal Diseases (22) · Infections (22) · Intestinal Diseases (22) · Intraabdominal Infections (22) · Pathological Conditions, Signs and Symptoms (5) · Pathologic Processes (4) · Suppuration (3) · Abscess (2) · Postoperative Complications (2) · Wound Infection (2) · Coronaviridae Infections (1) · Coronavirus Infections (1)
Ampicillin (3) · Metronidazole (3) · Amoxicillin-Potassium Clavulanate Combination (2) · Anti-Bacterial Agents (2) · Appendectomy (2) · Clavulanic Acid (2) · Clindamycin (2) · Gentamicins (2) · Piperacillin, Tazobactam Drug Combination (2) · Suction (2) · Acetaminophen (1) · Catheterization, Peripheral (1) · Ceftazidime (1) · Ceftriaxone (1) · Chewing Gum (1)
Children's Mercy Hospital Kansas City (4) · Assiut University (2) · Phoenix Children's Hospital (2) · University of Michigan (2) · Cirujanos la Serena (1) · Far Eastern Memorial Hospital (1) · Hospital Queen Elizabeth, Malaysia (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Marshall University (1) · Prisma Health-Upstate (1) · Ruhr University of Bochum (1) · The Affiliated Hospital of Qingdao University (1) · The University of Texas Health Science Center, Houston (1) · University Hospital Tuebingen (1) · Wake Forest University (1)
United States (12) · Chile (1) · China (1) · Germany (1) · Malaysia (1) · Taiwan (1)
Shawn D St. Peter, MD (2) · Benno Mann, PD Dr. med. (1) · Brant T Heniford, M.D. (1) · Craig Egan, MD (1) · Dalya Ferguson, MD, MS (1) · Daniel J Ostlie, MD (1) · Hari Sellappan, MB BCh BAO (1) · Heng-Fu Lin, MD (1) · Juan Sanabria, MD MSc FACS (1) · Justin Lee, MD (1) · Marcelo A Beltran, MD (1) · Michael Sand, Dr. med. (1) · Robert Gates, MD (1) · Rodrigo Barrera, MD (1) · Shawn D St. Peter (1)
PMID 19306980, PMID 39413050, PMID 6221925, PMID 8624197
K12TR004908 (1)