7 completed, 4 active not recruiting, 4 recruiting, 4 terminated. 14 Phase 2, 7 Not applicable, 3 Phase 1, 1 Phase 3.
Follow Paranasal Sinus Neoplasms: new trials by email Literature Review of Paranasal Sinus Neoplasms trials Research Report on Paranasal Sinus Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer SX-682, DTX - Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma | Phase 1 / Phase 2 | Recruiting | National Cancer Institute (NCI) | 120 | 2026-10-28 | 2026-10-23 |
| Evaluation of Endoscopic Management of Sinonasal Tumors In Difficult Anatomical Locations endoscopic approch - Nasal Cavity and Paranasal Sinus Cancer | Not applicable | Not yet recruiting | Assiut University | 25 | 2026-04-01 | 2026-04-06 |
| Toripalimab With Chemotherapy for Sinus Cancer Toripalimab, Carboplatin, Docetaxel - Sinonasal Cancer, Paranasal Sinus Neoplasms | Phase 2 | Recruiting | Dana-Farber Cancer Institute | 20 | 2025-06-17 | 2026-08-31 |
| Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to Drugs Stage III Breast Cancer, Stage IV Breast Cancer | Withdrawn | Travera Inc | 2024-11-01 | 2024-11-25 | ||
| Utility of Indocyanine Green Fluorescence in Endoscopic Sinonasal and Skull Base Surgery Sinonasal Benign or Malignant Tumor Resection, Skull Base Surgery (Assessment of Nasoseptal Flap), Endoscopic Sinus Surgery - Chronic Sinusitis, Tumor of Nasal Sinus | Not applicable | Unknown | St. Paul's Sinus Centre | 40 | 2023-01-01 | 2022-11-14 |
| The Head and Neck Registry of the European Reference Network on Rare Adult Solid Cancers observation - Head and Neck Cancer, Nasopharynx Cancer | Recruiting | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | 13600 | 2022-05-31 | 2026-04-03 | |
| Temporalis Myofascial Flap Effectiveness Temporalis Myofascial flap - Maxillary Sinus Neoplasms | Not applicable | Unknown | Assiut University | 3 | 2022-03-01 | 2022-03-28 |
| Induction Treatment in SCC of the Head and Neck Region - Concomitant Chemotherapy and Low-dose Radiotherapy Chemotherapy (carboplatin+paclitaxel) with concomitant low dose ionizing radiotherapy - Squamous Cell Carcinoma of Oral Cavity, Pharynx Carcinoma | Not applicable | Active not recruiting | Maria Sklodowska-Curie National Research Institute of Oncology | 40 | 2022-02-17 | 2026-10-16 |
| Intensity Modulated Proton or X-Ray Therapy After Surgery for Treatment of Head and Neck Cancer, the HEADLIGHT Study Cisplatin, Intensity-Modulated Proton Therapy, Quality-of-Life Assessment - Head and Neck Carcinoma, Head and Neck Carcinoma of Unknown Primary | Phase 2 | Active not recruiting | Mayo Clinic | 174 | 2022-02-16 | 2026-07-16 |
| Endoscopic Surgery in the Treatment of Soft Tissue Sarcoma in Nasal and Paranasal Sinus endoscopic surgery - Sarcoma,Soft Tissue, Nasal Cavity Cancer | Unknown | Eye & ENT Hospital of Fudan University | 40 | 2021-06-12 | 2022-11-14 | |
| Customized 3D Printed Oral Stents During Head and Neck Radiotherapy Best Practice, Medical Device Usage and Evaluation - Head and Neck Carcinoma, Malignant Parotid Gland Neoplasm | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 88 | 2021-05-26 | 2026-10-06 |
| Camrelizumab Plus Chemoradiotherapy for Patients With Locoregional Cancer of Nasal Cavity and Paranasal Sinuses camrelizumab - Nasal Cavity Cancer, Paranasal Sinus Cancer | Phase 2 | Unknown | Sun Yat-sen University | 57 | 2021-04-16 | 2021-11-10 |
| Exercise Training and Behavioral Modification for the Improvement of Physical Activity in Head and Neck Cancer Patients Undergoing Cancer Treatment Medical Device Usage and Evaluation, Consultation, Exercise Intervention - Head and Neck Carcinoma, Hypopharyngeal Carcinoma | Not applicable | Completed | Thomas Jefferson University | 12 | 2021-03-28 | 2025-05-22 |
| Celecoxib Through Surgery and Radiation Therapy for the Treatment of Advanced Head and Neck Cancer Celecoxib, Placebo, Quality-of-Life Assessment - Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Phase 2 | Terminated | University of Utah | 13 | 2019-11-27 | 2025-02-12 |
| A Clinical Trial of Endoscopic Surgery Followed by Chemotherapy and Proton Radiation for the Treatment of Tumors in the Sinus and Nasal Passages Cisplatin, Adjuvant Proton Radiotherapy, Endoscopic Resection - Paranasal Sinus Cancer, Nasal Cavity Tumor | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 3 | 2017-09-01 | 2025-05-16 |
| Adaptive Radiotherapy for Head and Neck Cancer Adaptive Radiotherapy - Head and Neck Cancer, Paranasal Sinus Cancer | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 64 | 2017-03-15 | 2021-10-26 |
| Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Biospecimen Collection, Computed Tomography, Echocardiography Test - Acinar Cell Carcinoma, Adenoid Cystic Carcinoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 798 | 2017-01-30 | 2026-06-17 |
| Olfactory Training in Improving Sense of Smell After Radiation Therapy in Patients With Paranasal Sinus or Nasopharyngeal Cancer Physiologic Testing, Quality-of-Life Assessment, Sham Intervention - Stage 0 Nasopharyngeal Carcinoma, Stage 0 Paranasal Sinus Cancer | Not applicable | Terminated | Stanford University | 15 | 2016-12-01 | 2019-02-05 |
| Integrated Cancer Repository for Cancer Research Pancreatic Cancer, Thyroid Cancer | Recruiting | University of Nebraska | 999999 | 2013-11-01 | 2026-06-29 | |
| Docetaxel, Cisplatin and Fluorouracil in Treating Patients With Previously Untreated Stage II-IV Nasal Cavity and Paranasal Sinus Cancer Carboplatin, Chemoradiotherapy, Cisplatin - Locally Advanced Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma, Nasal Cavity and Paranasal Sinus Poorly Differentiated Carcinoma | Phase 2 | Terminated | M.D. Anderson Cancer Center | 31 | 2008-06-16 | 2026-07-17 |
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Laryngeal Neoplasms (13) · Mouth Neoplasms (10) · Hypopharyngeal Neoplasms (8) · Oropharyngeal Neoplasms (8) · Head and Neck Neoplasms (7) · Salivary Gland Neoplasms (6) · Nasopharyngeal Neoplasms (5) · Pharyngeal Neoplasms (4) · Carcinoma (3) · Carcinoma, Adenoid Cystic (3) · Lung Neoplasms (3) · Maxillary Sinus Neoplasms (3) · Nasopharyngeal Carcinoma (3) · Prostatic Neoplasms (3)
Neoplasms (26) · Neoplasms by Site (26) · Nose Diseases (26) · Otorhinolaryngologic Diseases (26) · Otorhinolaryngologic Neoplasms (26) · Paranasal Sinus Diseases (26) · Respiratory Tract Diseases (26) · Respiratory Tract Neoplasms (26) · Nose Neoplasms (25) · Head and Neck Neoplasms (19) · Pharyngeal Diseases (17) · Stomatognathic Diseases (17) · Laryngeal Diseases (13) · Pharyngeal Neoplasms (13) · Mouth Diseases (12)
Cisplatin (6) · Radiotherapy (5) · Docetaxel (3) · Fluorouracil (3) · 1,2-diaminocyclohexaneplatinum II citrate (2) · Carboplatin (2) · Celecoxib (2) · Drug Therapy (2) · Hydroxyurea (2) · Magnetic Resonance Spectroscopy (2) · Platinum (2) · Specimen Handling (2) · Behavior Therapy (1) · CP protocol (1) · CTLA-4 Antigen (1)
Assiut University (2) · Johnny Kao (2) · M.D. Anderson Cancer Center (2) · Memorial Sloan Kettering Cancer Center (2) · National Cancer Institute (NCI) (2) · Burzynski Research Institute (1) · Dana-Farber Cancer Institute (1) · Eye & ENT Hospital of Fudan University (1) · Fondazione IRCCS Istituto Nazionale dei Tumori, Milano (1) · Maria Sklodowska-Curie National Research Institute of Oncology (1) · Mayo Clinic (1) · Ohio State University Comprehensive Cancer Center (1) · St. Paul's Sinus Centre (1) · Stanford University (1) · Sun Yat-sen University (1)
United States (17) · China (2) · Croatia (1) · Czechia (1) · Egypt (1) · France (1) · Germany (1) · Guam (1) · Italy (1) · Poland (1) · Russia (1) · Spain (1)
Amit Agrawal (1) · Anna Lee (1) · Annalisa Trama, MD (1) · C. Jillian Tsai, MD (1) · Charalampos Floudas, M.D. (1) · Ehab Y Hanna (1) · Everett Vokes, M.D. (1) · Johnny Kao, M.D. (1) · Johnny Kao, MD (1) · Kartik Sehgal, MD (1) · Kurt Fisher, MD, PhD (1) · Marc Cohen, MD (1) · Mark Stevens, Ph.D. (1) · Richard Cannon, MD (1)
PMID 20830768, PMID 21246519, PMID 31969335, PMID 33362722, PMID 33882143, PMID 34380663, PMID 34716198, PMID 36928072, PMID 38243705, PMID 38358334, PMID 39067873, PMID 39343510, PMID 39417692, PMID 39583952, PMID 39856213, PMID 40402690, PMID 40588371, PMID 41672597, PMID 41892875, PMID 41995270, PMID 42499790
P30CA042014 (1), U10CA180888 (1)