5 unknown, 4 completed, 3 not yet recruiting, 3 recruiting. 4 Phase 2, 3 Phase 1, 2 Not applicable, 2 Phase 4, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Not yet recruiting 2, Completed 1, Unknown 1 |
| Phase 1 | 3 | Unknown 2, Completed 1 |
| Not applicable | 2 | Not yet recruiting 1, Unknown 1 |
| Phase 4 | 2 | Completed 1, Unknown 1 |
| Phase 3 | 1 | Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase II Study of Ivonescimab Combined With Intraperitoneal Paclitaxel in Patients With High-Grade Metastatic Appendiceal Adenocarcinoma (AA) Ivonescimab, IP PTX - Phase II, Ivonescimab | Phase 2 | Not yet recruiting | M.D. Anderson Cancer Center | 30 | 2027-01-16 | 2026-08-27 |
| Oral Paclitaxel as Neoadjuvant Therapy in Elderly NSCLC: A Phase II Trial Paclitaxel Oral Solution - Non-Small-Cell Lung Cancer, Neoadjuvant Therapy | Not applicable | Not yet recruiting | Shanghai Pulmonary Hospital, Shanghai, China | 75 | 2026-06-08 | 2026-05-20 |
| Registry of Coronary Disease Outcomes Revascularizing With Drug-Coated Balloons Percutaneous Coronary Intervention (PCI), Drug Coated Balloon | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 3000 | 2025-11-11 | 2025-11-17 | |
| Intratumoral Gemcitabine, Paclitaxel, Carboplatine and Intravenous Nivolumab for Locally Recurrence of Head and Neck Cancers GCP intratumoral catheter - Squamous Cell Carcinoma of the Head and Neck, Paclitaxel | Phase 2 | Not yet recruiting | Centre Hospitalier Universitaire, Amiens | 39 | 2025-11-01 | 2025-03-21 |
| Effect of Alpha Lipoic Acid on Chemotherapy Induced Neurological Changes in Breast Cancer Patients Alpha Lipoic Acid 600 MG Oral Capsule - Breast Cancer, Alpha Lipoic Acid | Phase 4 | Unknown | Ain Shams University | 92 | 2024-04-01 | 2024-05-09 |
| A Phase I Dose-finding Trial of Hyperthermic Intraperitoneal Paclitaxel Combined With Cisplatin Hyperthermic Intraperitoneal Paclitaxel Combined With Cisplatin - Ovarian Cancer, Hyperthermic Intraperitoneal Chemotherapy | Phase 1 | Unknown | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 30 | 2022-12-01 | 2022-11-17 |
| Chiauranib Plus Weekly Paclitaxel in Patients with Platinum-refractory or Platinum-resistant Recurrent Ovarian Cancer chiauranib, Placebo, Paclitaxel - Ovarian Cancer, Relapsed or Refractory | Phase 3 | Recruiting | Chipscreen Biosciences, Ltd. | 454 | 2021-12-20 | 2024-10-18 |
| Intraperitoneal Paclitaxel With XELOX in Gastric Cancer With Peritoneal Metastasis Paclitaxel - Stomach Neoplasms, Paclitaxel | Phase 1 / Phase 2 | Unknown | Seoul St. Mary's Hospital | 61 | 2021-06-08 | 2021-07-06 |
| European All-comers' Multicentric Prospective REGISTRY on LUMINOR© Drug Eluting Balloon in the Superficial Femoral Artery and Popliteal Artery With 5 Years Follow-up. LUMINOR© Paclitaxel eluting balloon - Angioplasty, Peripheral Arterial Disease | Unknown | iVascular S.L.U. | 500 | 2021-01-18 | 2021-02-11 | |
| Predicting Peripheral Neuropathy of Paclitaxel for Gastric Cancer Paclitaxel - Gastric Cancer, Chemotherapy-induced Peripheral Neuropathy | Recruiting | City of Hope Medical Center | 150 | 2018-10-01 | 2026-07-07 | |
| Predicting the Efficacy in Advanced Gastric Cancer. Paclitaxel - Gastric Cancer, Chemotherapy Effect | Completed | City of Hope Medical Center | 162 | 2018-10-01 | 2025-07-18 | |
| Drug Eluting Balloon Angioplasty Versus Nitinol Stent Implantation in the Superficial Femoral Artery Drug Eluting Balloon Angioplasty, Nitinol stenting - Peripheral Arterial Disease, Arterial Occlusive Diseases | Phase 4 | Completed | Instituto Dante Pazzanese de Cardiologia | 85 | 2014-07-01 | 2021-06-10 |
| Paclitaxol Every 2 Week Versus Paclitaxol Every 1 Week in the Adjuvant Treatment of Breast Cancer paclitaxel - Breast Cancer, Paclitaxel | Not applicable | Unknown | Taizhou Hospital | 1000 | 2013-05-01 | 2013-05-07 |
| Study to Assess the Safety and Tolerability of a PARP Inhibitor in Combination With Carboplatin and/or Paclitaxel KU-0059436 (AZD2281)(PARP inhibitor), Carboplatin, Paclitaxel - Triple Negative Metastatic Breast Cancer, Advanced Ovarian Cancer | Phase 1 | Completed | AstraZeneca | 189 | 2007-06-22 | 2025-04-11 |
| CCRT for Esophageal Cancer. Paclitaxel, Oxaliplatin, Radiotherapy - Esophageal Cancer, Concurrent Chemoradiotherapy | Phase 2 | Completed | Hangzhou Cancer Hospital | 34 | 2005-01-01 | 2016-02-17 |
Stomach Neoplasms (3) · Breast Neoplasms (2) · Ovarian Neoplasms (2) · Peripheral Arterial Disease (2) · Acute Coronary Syndrome (1) · Adenocarcinoma, Mucinous (1) · Arterial Occlusive Diseases (1) · Arteriosclerosis (1) · Atherosclerosis (1) · Carcinoma, Non-Small-Cell Lung (1) · Cardiovascular Diseases (1) · Chronic Limb-Threatening Ischemia (1) · Coronary Artery Disease (1) · Esophageal Neoplasms (1) · Myocardial Infarction (1)
Neoplasms (11) · Neoplasms by Site (10) · Digestive System Diseases (4) · Digestive System Neoplasms (4) · Gastrointestinal Diseases (4) · Gastrointestinal Neoplasms (4) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Stomach Diseases (3) · Vascular Diseases (3) · Adnexal Diseases (2) · Arterial Occlusive Diseases (2) · Arteriosclerosis (2) · Breast Diseases (2) · Carcinoma (2)
Paclitaxel (8) · Oxaliplatin (2) · Ramucirumab (2) · CP protocol (1) · Capecitabine (1) · Carboplatin (1) · Cisplatin (1) · Radiotherapy (1) · Thioctic Acid (1) · chiauranib (1) · olaparib (1)
City of Hope Medical Center (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Ain Shams University (1) · AstraZeneca (1) · Centre Hospitalier Universitaire, Amiens (1) · Chipscreen Biosciences, Ltd. (1) · Hangzhou Cancer Hospital (1) · Instituto Dante Pazzanese de Cardiologia (1) · M.D. Anderson Cancer Center (1) · Seoul St. Mary's Hospital (1) · Shanghai Pulmonary Hospital, Shanghai, China (1) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (1) · Taizhou Hospital (1) · iVascular S.L.U. (1)
China (2) · France (2) · Japan (2) · Netherlands (2) · United States (2) · Belgium (1) · Brazil (1) · Egypt (1) · South Korea (1) · United Kingdom (1)
Koichi Takiguchi, PhD (2) · Beth Helmink, MD (1) · Dr Johann de Bono, MD (1) · Feilin Cao, MD (1) · Jane Robertson, BSc, MBCHB, MD (1) · Manal H El Hamamsy, Doctorate (1) · Prof Jan HM Schellens (1) · Xiaohua Wu (1)
PMID 12457622, PMID 15135924, PMID 17131349, PMID 19786984, PMID 21073761, PMID 21600374, PMID 22149222, PMID 22248721, PMID 22619725, PMID 24777126, PMID 29291932, PMID 30264707, PMID 30721699, PMID 30850285, PMID 31637669, PMID 31651976, PMID 31667659, PMID 32554133, PMID 33249205, PMID 33705788, PMID 33985854, PMID 34562992, PMID 35510329, PMID 35596774, PMID 36382727, PMID 39477043, PMID 9378235