8 recruiting, 4 active not recruiting, 4 completed, 4 not yet recruiting. 9 Phase 2, 5 Not applicable, 4 Phase 1, 1 Phase 3, 1 Phase 4.
Follow Oropharyngeal Carcinoma: new trials by email Literature Review of Oropharyngeal Carcinoma trials Research Report on Oropharyngeal Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Off-line Adaptive Proton Therapy Off-line Adaptive Proton Therapy (o-APT) Workflow Evaluation - Oropharyngeal Carcinoma | Not yet recruiting | University Medical Center Groningen | 100 | 2026-10-01 | 2026-10-08 | |
| Intraoperative Methadone for the Management of Postoperative Pain in Patients With Head and Neck Cancers Electronic Health Record Review, Fentanyl, Laryngoscopy - Head and Neck Carcinoma, Hypopharyngeal Carcinoma | Phase 4 | Recruiting | OHSU Knight Cancer Institute | 58 | 2026-09-22 | 2026-10-05 |
| SPECT-CT Guided ELEctive Contralateral Neck Treatment in Lateralized Oropharyngeal Cancer Lymphatic mapping with SPECT-CT, Bilateral neck radiotherapy, Ipsilateral neck radiotherapy & SPECT-CT guided contralateral neck radiotherapy - Oropharyngeal Squamous Cell Carcinoma, Oropharyngeal Cancers | Not applicable | Not yet recruiting | UNICANCER | 128 | 2026-09-01 | 2026-07-21 |
| Thermotherapy for Head and Neck Cancer Patients Thermotherapy, Radiotherapy, Concurrent chemoradiation - Head and Neck Cancer, Oropharyngeal Carcinoma | Phase 1 | Recruiting | Erasmus Medical Center | 30 | 2026-09-01 | 2026-09-02 |
| A Single Arm Phase II Trial in p16-positive Oropharynx Cancer of Selective Dose De-escalation of nodAl VolumEs at Minimal Risk and Primary Site Disease (SAVED) Dose de-escalation to contralateral neck., Dose de-escalation to gross disease to contralateral neck, Dose de-escalation to gross disease - Head and Neck Cancer, Head and Neck Squamous Cell Cancer | Phase 2 | Not yet recruiting | University of Maryland, Baltimore | 132 | 2026-09-01 | 2026-08-14 |
| Transoral and Cervical Ultrasound of Patients With Suspected Oropharyngeal Cancer Ultrasound of the oropharynx - Oropharyngeal Carcinoma, Ultrasound | Not applicable | Recruiting | Tobias Todsen | 180 | 2025-08-20 | 2026-04-23 |
| Transmission of Oncogenic HPV Infection Among Families Human Papilloma Virus (HPV), Cervical Carcinoma | Not yet recruiting | Tampere University Hospital | 700 | 2025-08-01 | 2025-06-25 | |
| A Study of Reduced Radiation Therapy With Chemotherapy in People With HPV-Positive Throat Cancer 18F-FMISO PET/CT Scan, Chemoradiation, Questionnaires - Oropharyngeal Carcinoma | Phase 2 | Recruiting | Memorial Sloan Kettering Cancer Center | 74 | 2025-05-13 | 2026-05-11 |
| Thermotherapy for Locally Advanced Head and Neck Cancer Thermotherapy, radiotherapy - Head and Neck Cancer, Oropharyngeal Carcinoma | Phase 1 | Active not recruiting | Erasmus Medical Center | 2 | 2025-05-01 | 2026-09-02 |
| Can Recurrence of Cancer in the Oropharynx be Detected by Blood Samples? Liquid biopsy - Oropharynx Cancer, Oropharynx Cancer, Metastatic | Active not recruiting | Copenhagen University Hospital, Rigshospitalet | 200 | 2024-04-02 | 2025-11-18 | |
| Multidimensional and Multimodal Profiling of Oropharyngeal Carcinoma Oropharyngeal Carcinoma, Human Papilloma Virus | Recruiting | Stanford University | 1000 | 2023-07-07 | 2026-09-15 | |
| A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat Cancer 18 F-FMISO PET/CT, Radiation, Cisplatin - HPV, Throat Cancer | Phase 2 | Recruiting | Memorial Sloan Kettering Cancer Center | 121 | 2022-08-04 | 2026-04-23 |
| Intensity Modulated Proton or X-Ray Therapy After Surgery for Treatment of Head and Neck Cancer, the HEADLIGHT Study Cisplatin, Intensity-Modulated Proton Therapy, Quality-of-Life Assessment - Head and Neck Carcinoma, Head and Neck Carcinoma of Unknown Primary | Phase 2 | Active not recruiting | Mayo Clinic | 174 | 2022-02-16 | 2026-07-16 |
| Exercise Training and Behavioral Modification for the Improvement of Physical Activity in Head and Neck Cancer Patients Undergoing Cancer Treatment Medical Device Usage and Evaluation, Consultation, Exercise Intervention - Head and Neck Carcinoma, Hypopharyngeal Carcinoma | Not applicable | Completed | Thomas Jefferson University | 12 | 2021-03-28 | 2025-05-22 |
| Patient Reported Outcome Post Radiation Therapy or Chemoradiotherapy Patient Care in Patients With Oropharyngeal Cancer Electronic Health Record Review, Questionnaire Administration - Oropharyngeal Carcinoma | Active not recruiting | M.D. Anderson Cancer Center | 77 | 2021-03-10 | 2026-07-16 | |
| Toripalimab Based Induction Chemotherapy Followed by De-escalation Protocols in HPV-related OPSCC Toxicities reduced treatment arm - Oropharyngeal Carcinoma, Immune Checkpoint Inhibitor | Not applicable | Unknown | Fudan University | 46 | 2021-02-01 | 2021-04-30 |
| High Dose Steroid Therapy (Prednisone or Methylprednisolone) for the Improvement of Symptoms of Late Radiation-Associated Lower Cranial Neuropathy in Oropharyngeal Cancer Survivors Methylprednisolone, Prednisone, Quality-of-Life Assessment - Cranial Nerve Disorder, Head and Neck Carcinoma | Phase 1 / Phase 2 | Recruiting | M.D. Anderson Cancer Center | 35 | 2019-10-16 | 2026-06-26 |
| De-escalation Protocols in HPV-related Oropharyngeal Carcinoma in Chinese Populations Toxicities reduced treatment, conventional treatment - Oropharyngeal Carcinoma, De-escalation | Not applicable | Unknown | Fudan University | 83 | 2019-07-01 | 2019-07-09 |
| Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer INBRX-105 - PDL1x41BB antibody, Pembrolizumab - Metastatic Solid Tumors, Non-small Cell Lung Cancer | Phase 1 | Terminated | Inhibrx Biosciences, Inc | 160 | 2019-01-30 | 2024-10-23 |
| Adaptive Treatment De-escalation in Favorable Risk HPV-Positive Oropharyngeal Carcinoma Standard Radiation Treatment, Dose-Deescalated Treatment, Cisplatinum - Oropharyngeal Carcinoma, HPV Positive Oropharyngeal Squamous Cell Carcinoma | Phase 2 | Recruiting | NYU Langone Health | 120 | 2017-10-18 | 2026-01-06 |
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Oropharyngeal Neoplasms (24) · Mouth Neoplasms (7) · Head and Neck Neoplasms (6) · Squamous Cell Carcinoma of Head and Neck (6) · Hypopharyngeal Neoplasms (5) · Laryngeal Neoplasms (5) · Hyperthermia (2) · Lung Neoplasms (2) · Papillomavirus Infections (2) · Paranasal Sinus Neoplasms (2) · Adenocarcinoma Of Esophagus (1) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Renal Cell (1) · Carcinoma, Transitional Cell (1) · Cranial Nerve Diseases (1)
Neoplasms (24) · Neoplasms by Site (24) · Otorhinolaryngologic Diseases (24) · Otorhinolaryngologic Neoplasms (24) · Pharyngeal Diseases (24) · Pharyngeal Neoplasms (24) · Stomatognathic Diseases (24) · Head and Neck Neoplasms (18) · Mouth Diseases (7) · Carcinoma (6) · Carcinoma, Squamous Cell (6) · Neoplasms by Histologic Type (6) · Neoplasms, Glandular and Epithelial (6) · Pathological Conditions, Signs and Symptoms (6) · Respiratory Tract Diseases (6)
Radiotherapy (4) · Cisplatin (3) · Diathermy (2) · Hyperthermia, Induced (2) · Radiotherapy, Intensity-Modulated (2) · 1,2-diaminocyclohexaneplatinum II citrate (1) · Behavior Therapy (1) · Carboplatin (1) · Chemoradiotherapy (1) · Fentanyl (1) · Fluorouracil (1) · Laryngoscopy (1) · Liquid Biopsy (1) · Magnetic Resonance Spectroscopy (1) · Medrol Veriderm (1)
Fudan University (3) · Erasmus Medical Center (2) · M.D. Anderson Cancer Center (2) · Memorial Sloan Kettering Cancer Center (2) · Shanghai Jiao Tong University School of Medicine (2) · Stanford University (2) · Copenhagen University Hospital, Rigshospitalet (1) · Inhibrx Biosciences, Inc (1) · Mayo Clinic (1) · NYU Langone Health (1) · OHSU Knight Cancer Institute (1) · Tampere University Hospital (1) · Thomas Jefferson University (1) · Tobias Todsen (1) · UNICANCER (1)
United States (11) · China (5) · Netherlands (3) · Denmark (2) · Finland (1) · France (1)
Chen-ping Zhang, MD, PhD (2) · Michiel Kroesen, MD, Dr. (2) · Nancy Lee, MD (2) · Chaosu Hu, MD (1) · Chris Holsinger (1) · Chris Holsinger, MD (1) · Christian von Buchwald, Professor, MD, DMSci (1) · Jason K Molitoris (1) · Karolina Louvanto, Professor (1) · Katherine A Hutcheson, BA,MS,PHD (1) · Kenneth Hu, MD (1) · Ryan N Hellums (1) · Scott C. Lester, M.D. (1)