7 completed, 1 withdrawn. 8 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 7, Withdrawn 1 |
| Phase 2 | 1 | Completed 1 |
Follow Olfactory Nerve Diseases: new trials by email Literature Review of Olfactory Nerve Diseases trials Research Report on Olfactory Nerve Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Doxepin Hydrochloride in Treating Oral Mucositis Pain in Patients With Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy doxepin hydrochloride, placebo - Head and Neck Cancer, Mucositis | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 155 | 2010-12-01 | 2017-08-09 |
| Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Fentanyl sublingual spray, Placebo - Cancer | Phase 3 | Completed | INSYS Therapeutics Inc | 130 | 2007-10-01 | 2014-03-05 |
| GM-CSF Mouthwash for Preventing and Treating Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer sargramostim, oral salt and soda mouthwash - Head and Neck Cancer, Mucositis Oral | Phase 3 | Completed | Marilyn Dodd | 91 | 2005-06-07 | 2021-07-30 |
| Acupuncture or Standard Therapy in Treating Pain and Dysfunction in Patients Who Have Undergone Neck Surgery for Head and Neck Cancer acupuncture therapy, standard follow-up care - Head and Neck Cancer, Pain | Phase 3 | Completed | Memorial Sloan Kettering Cancer Center | 73 | 2003-11-01 | 2013-03-07 |
| Cevimeline in Treating Patients With Dry Mouth Caused by Radiation Therapy for Head and Neck Cancer cevimeline hydrochloride - Head and Neck Cancer, Oral Complications | Phase 3 | Completed | Daiichi Sankyo | 2001-06-01 | 2012-05-16 | |
| Megestrol to Limit Weight Loss and Improve Quality of Life in Treating Patients With Head and Neck Cancer megestrol acetate, quality-of-life assessment - Anorexia, Cachexia | Phase 3 | Completed | Wake Forest University Health Sciences | 13 | 2000-10-01 | 2021-09-09 |
| Fluconazole in Preventing Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer fluconazole, radiation therapy - Head and Neck Cancer, Infection | Phase 2 / Phase 3 | Completed | University of Miami | 1993-02-01 | 2016-12-15 | |
| Docetaxel and St. John's Wort in Treating Patients With Solid Tumors That Cannot Be Removed By Surgery Hypericum perforatum, docetaxel, placebo - Adult Solid Tumor, Breast Cancer | Phase 3 | Withdrawn | Alliance for Clinical Trials in Oncology | 2016-07-12 |
Esthesioneuroblastoma, Olfactory (8) · Head and Neck Neoplasms (7) · Squamous Cell Carcinoma of Head and Neck (7) · Salivary Gland Neoplasms (5) · Pain (3) · Breast Neoplasms (2) · Carcinoma, Non-Small-Cell Lung (2) · Prostatic Neoplasms (2) · Radiation Injuries (2) · Small Cell Lung Carcinoma (2) · Tongue Neoplasms (2) · Urinary Bladder Neoplasms (2) · Adrenocortical Carcinoma (1) · Anorexia (1) · Anus Neoplasms (1)
Cranial Nerve Diseases (8) · Neoplasms by Histologic Type (8) · Neoplasms by Site (8) · Neoplasms, Germ Cell and Embryonal (8) · Neoplasms, Glandular and Epithelial (8) · Neoplasms, Nerve Tissue (8) · Neoplasms, Neuroepithelial (8) · Nervous System Diseases (8) · Neuroblastoma (8) · Neuroectodermal Tumors (8) · Carcinoma (7) · Carcinoma, Squamous Cell (7) · Neoplasms (7) · Neuroectodermal Tumors, Primitive (7)
Acupuncture Therapy (1) · Docetaxel (1) · Doxepin (1) · Fentanyl (1) · Fluconazole (1) · Hypericum extract LI 160 (1) · Megestrol Acetate (1) · Radiotherapy (1) · Salts (1) · cevimeline (1) · sargramostim (1)
Alliance for Clinical Trials in Oncology (2) · Daiichi Sankyo (1) · INSYS Therapeutics Inc (1) · Marilyn Dodd (1) · Memorial Sloan Kettering Cancer Center (1) · University of Miami (1) · Wake Forest University Health Sciences (1)
United States (7)
Arnold M. Markoe, MD, ScD (1) · David G. Pfister, MD (1) · Kathryn M. Greven, MD (1) · Larry Dillaha, MD (1) · Lionel D. Lewis, MD (1) · Marylin J. Dodd, RN, PhD (1) · Robert C. Miller, MD (1) · Robert Vitti, MD (1)
PMID 20406930, PMID 22480131, PMID 24733799, PMID 27020837
P30CA008748 (1), R01CA107080 (1), R21CA098792 (1), U10CA037404 (1)