29 completed, 9 unknown, 3 active not recruiting, 1 not yet recruiting. 21 Not applicable, 6 Phase 1, 6 Phase 4, 5 Phase 3, 3 Phase 2.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparing The PK Of Aramchol Meglumine Granules To Aramchol Free Acid Tablets Aramchol meglumine, Aramchol free acid - Healthy | Phase 1 | Completed | Galmed Pharmaceuticals Ltd | 16 | 2025-02-15 | 2026-06-01 |
| Reducing Salt and Sugar in Campus Foods: A Malaysian Study Reduction in Salt and Sugar, The potentiometer, Dry Ashing Method Followed by Flame Atomic Absorption Spectrometry (FAAS) - Cardiovascular Diseases | Not applicable | Not yet recruiting | Sunway University | 300 | 2024-07-01 | 2024-06-25 |
| Immediate Pressor Response to Oral Salt salt - High Blood Pressure | Not applicable | Unknown | Mulungushi University | 300 | 2023-07-07 | 2024-01-26 |
| Salt Intake, Hydration Status and Gastrointestinal Discomfort During Fasting Salt 3 g, Salt 6 g, Salt 9 g - Healthy | Not applicable | Completed | Oxford Brookes University | 23 | 2023-02-14 | 2023-09-06 |
| Increasing Vegetable Intake Using Monosodium Glutamate: A Reduced-Effort Intervention Salt replacement seasoning (50% salt and 50% MSG) mix, Salt replacement seasoning (70% salt and 30% MSG) mix, NaCl (sodium chloride/table salt) - Healthy Nutrition, Culinary Medicine | Not applicable | Completed | Texas Tech University | 148 | 2023-02-10 | 2024-08-01 |
| Feasibility, Acceptability and Directional Signal Effect on Blood Folate Levels of Iodized Salt Fortified With Folic Acid: Clinical Study Salt with folic acid and iodine - Neural Tube Defects, Folic Acid Deficiency | Not applicable | Completed | University of Alabama at Birmingham | 32 | 2023-01-24 | 2023-08-01 |
| Effects of Triptorelin Pamoate 6-month When Given to Adult Chinese Participants With Advanced Cancer in the Prostate Triptorelin pamoate (embonate) salt - Advanced Prostate Cancer, Metastatic Prostate Cancer | Phase 3 | Completed | Ipsen | 195 | 2022-11-17 | 2025-09-09 |
| Fluid Loading Countermeasures Salt Tablets, Electrolyte Solution - Healthy | Not applicable | Unknown | National Aeronautics and Space Administration (NASA) | 15 | 2022-04-01 | 2024-07-10 |
| Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis 100% Aloe Vera Juice, Magic Mouthwash, Salt and Baking soda rinse - Oral Cavity Cancer, Head and Neck Cancers - Tonsils | Phase 3 | Completed | Covenant Health Cancer Center | 100 | 2022-01-20 | 2024-10-10 |
| Salt Supplementation in Gitelman Syndrome Salt (NaCl), Placebo - Gitelman Syndrome | Not applicable | Completed | Radboud University Medical Center | 21 | 2021-04-19 | 2024-11-21 |
| Medicinal vs. Orthotic Comparison for Migraine Prevention: A Double-Blind Study Fremanezumab-Vfrm, BLAfit®, Saline - Migraine | Not applicable | Unknown | Manhattan Beach Orthodontics | 80 | 2021-02-01 | 2021-01-22 |
| Salt Intake, Microbiota, Immune Response and Endothelial Function in Hypertension Low salt diet plus sodium chloride supplements, Low salt diet plus placebo - Hypertension | Not applicable | Unknown | Hospital Clínico Universitario de Valladolid | 25 | 2020-12-01 | 2021-02-12 |
| Wishing to Decrease Aquaresis in ADPKD Patients Treated With a V2Ra; the Effect of Regulating Protein and Salt Sodiumchloride, Protein, Placebo comparator (salt) - Polycystic Kidney, Autosomal Dominant, ADPKD | Not applicable | Unknown | Esther Meijer | 12 | 2020-09-07 | 2020-11-05 |
| Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Selinexor, Temozolomide, Generic Radiation therapy (RT) - Gliosarcoma, Newly Diagnosed | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 11 | 2020-07-07 | 2026-01-23 |
| Open-Label Study to Evaluate the Safety, Tolerability, and PK of Aramchol in Subjects With Hepatic Impairment Aramchol free acid tablet 600mg, single dose, Aramchol free acid tablet 300mg, bid - Hepatic Impairment | Phase 1 | Completed | Galmed Research and Development, Ltd. | 57 | 2020-02-13 | 2024-08-14 |
| Dietary Salt in Rheumatoid Arthritis salt - Rheumatoid Arthritis | Not applicable | Completed | Vanderbilt University Medical Center | 18 | 2020-01-02 | 2026-07-30 |
| Potential Harms of Untargeted Iron Supplementation in Cambodia Where Iron Deficiency is Not the Cause of Anemia Ferrous sulfate, Ferrous Bisglycinate, Placebo of microcrystalline cellulose - Anemia, Iron Deficiency, Anemia | Phase 4 | Completed | University of British Columbia | 480 | 2019-12-10 | 2024-05-08 |
| Self-administered Questionnaire to Evaluate Salt and Potassium Diet of Patients Followed in Nephrology Salt and potassium Diet - Nephropathy, Chronic Tubulointerstitial | Completed | Hospices Civils de Lyon | 542 | 2019-10-11 | 2020-09-17 | |
| Intralipid® 20% for Reversal of Local Anesthetics Lidocaine 2%, Lidocaine 1%, Bupivacaine 0.25% - Anesthesia, Local | Phase 4 | Active not recruiting | Hospital for Special Surgery, New York | 18 | 2019-07-26 | 2025-12-08 |
| Survivin Long Peptide Vaccine in Treating Patients With Metastatic Neuroendocrine Tumors Incomplete Freund's Adjuvant, Octreotide Acetate, Sargramostim - Lung Atypical Carcinoid Tumor, Lung Typical Carcinoid Tumor | Phase 1 | Completed | Roswell Park Cancer Institute | 19 | 2019-06-17 | 2026-02-06 |
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Hypertension (4) · Acute Kidney Injury (1) · Adenoma, Islet Cell (1) · Anemia (1) · Anemia, Iron-Deficiency (1) · Aphasia (1) · Arthritis, Rheumatoid (1) · Asthma (1) · Behavior (1) · Carcinoma, Medullary (1) · Carcinoma, Merkel Cell (1) · Cardiovascular Diseases (1) · Cystic Fibrosis (1) · Diabetes Mellitus, Type 2 (1) · Esophageal Neoplasms (1)
National Cancer Institute (NCI) (4) · Charite University, Berlin, Germany (2) · Vanderbilt University Medical Center (2) · Bayside Health (1) · Covenant Health Cancer Center (1) · Esther Meijer (1) · First Affiliated Hospital Xi'an Jiaotong University (1) · Funch-Jensen, Peter, M.D., D.M.Sc. (1) · Galmed Pharmaceuticals Ltd (1) · Galmed Research and Development, Ltd. (1) · Hospices Civils de Lyon (1) · Hospital Clínico Universitario de Valladolid (1) · Hospital de Clinicas de Porto Alegre (1) · Hospital for Special Surgery, New York (1) · Ipsen (1)
United States (17) · Canada (4) · United Kingdom (3) · France (2) · Germany (2) · Netherlands (2) · Australia (1) · Bulgaria (1) · Cambodia (1) · China (1) · Denmark (1) · Italy (1) · Nepal (1) · Spain (1) · Switzerland (1)
Anastasia Arynchyna-Smith, MPH (1) · Anja Maehler, PhD (1) · Argye B Hillis-Trupe, MD, MA (1) · Armando Coca, MD, MSc, phD (1) · Charles M Stein, MBChB (1) · Christoph Beglinger, MD (1) · Daniel Scaperoth, MD (1) · David Benton, DSc (1) · Esther Meijer, Dr. (1) · Eugene Kennedy, MD (1) · Francois A Allaert, MD (1) · James C Yao (1) · James M Luther, MD (1) · James Yao (1)
PMID 20335545, PMID 22978814, PMID 23059770, PMID 23689381, PMID 25058146, PMID 25628520, PMID 25900182, PMID 28384065, PMID 28985241, PMID 29859084, PMID 30611255, PMID 32801202, PMID 33375942, PMID 33783375, PMID 35057434, PMID 36912144, PMID 37199608, PMID 37271416, PMID 37592860, PMID 38281579, PMID 39356039, PMID 40535918, PMID 40690753, PMID 41082982
P30CA016672 (1), R01CA107080 (1), R01HL140145 (1), U01CA062461 (1), U10CA031946 (1), U10CA032102 (1), U10CA180821 (1), U10CA180888 (1)