4 completed, 2 terminated, 1 not yet recruiting, 1 unknown. 9 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 9 | Completed 4, Terminated 2, Not yet recruiting 1, Unknown 1, Withdrawn 1 |
Follow Neuropathy: new trials by email Literature Review of Neuropathy trials Research Report on Neuropathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Glutamine for the Prophylaxis of Vincristine-induced Neuropathy in Children and Adolescents With Cancer. Glutamine (Pharmacological doses) - Neuropathy, Cancer | Phase 3 | Not yet recruiting | Ain Shams University | 70 | 2025-12-30 | 2025-12-17 |
| Vit D3 and Omega 3 in Chemo Induced Neuropathy mammalian Omega 3 Fatty acids, placebo - Cancer, Neuropathy | Phase 3 | Unknown | McGill University Health Centre/Research Institute of the McGill University Health Centre | 600 | 2015-01-01 | 2015-04-07 |
| Prevention of Oxaliplatin-induced Neuropathic Pain by a Specific Diet Polyamines depleted diet, associating Polydol® cans and predefined menus low in polyamines - Neuropathy, Digestive Cancer System | Phase 3 | Completed | University Hospital, Clermont-Ferrand | 80 | 2013-02-02 | 2017-07-11 |
| Acetyl-L-Carnitine Hydrochloride in Preventing Peripheral Neuropathy in Patients With Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cavity Cancer, or Fallopian Tube Cancer Undergoing Chemotherapy Acetyl-L-Carnitine Hydrochloride, Placebo, Questionnaire Administration - Fatigue, Malignant Ovarian Mixed Epithelial Tumor | Phase 3 | Withdrawn | Gynecologic Oncology Group | 2012-04-01 | 2014-12-31 | |
| Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy calcium gluconate, magnesium sulfate, placebo - Chemotherapeutic Agent Toxicity, Colorectal Cancer | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 362 | 2010-06-01 | 2022-11-03 |
| Pregabalin Versus Placebo In The Treatment Of Neuropathic Pain Associated With HIV Neuropathy pregabalin, placebo - Neuropathy | Phase 3 | Terminated | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 377 | 2010-04-01 | 2021-01-28 |
| Glutathione in Preventing Peripheral Neuropathy Caused by Paclitaxel and Carboplatin in Patients With Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer Carboplatin, Glutathione, Laboratory Biomarker Analysis - Chemotherapeutic Agent Toxicity, Neuropathy | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 195 | 2009-12-01 | 2017-02-23 |
| Calcium and Magnesium in Preventing Peripheral Neuropathy Caused by Ixabepilone in Patients With Breast Cancer Calcium Gluconate, Magnesium Sulfate, Placebo - Neuropathy, Pain | Phase 3 | Terminated | Mayo Clinic | 1 | 2009-11-01 | 2016-02-04 |
| S0715: Acetyl-L-Carnitine in Preventing Neuropathy in Women With Stage I, II, or IIIA Breast Cancer Undergoing Chemo acetyl-L-carnitine hydrochloride, placebo - Breast Cancer, Chemotherapeutic Agent Toxicity | Phase 3 | Completed | SWOG Cancer Research Network | 437 | 2009-09-01 | 2017-08-14 |
Neurotoxicity Syndromes (4) · Pain (4) · Breast Neoplasms (2) · Fallopian Tube Neoplasms (2) · Fatigue (2) · Neoplasms (2) · Ovarian Neoplasms (2) · Brenner Tumor (1) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Digestive System Neoplasms (1) · HIV Infections (1) · Hyperalgesia (1) · Paresthesia (1) · Rectal Neoplasms (1)
Neoplasms (6) · Neoplasms by Site (6) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Nervous System Diseases (5) · Neurologic Manifestations (5) · Chemically-Induced Disorders (4) · Poisoning (4) · Genital Diseases (3) · Urogenital Diseases (3) · Adnexal Diseases (2) · Breast Diseases (2) · Digestive System Diseases (2) · Endocrine Gland Neoplasms (2) · Endocrine System Diseases (2)
Calcium Gluconate (2) · Magnesium Sulfate (2) · Calcium (1) · Carboplatin (1) · Glutamine (1) · Glutathione (1) · Oxaliplatin (1) · Paclitaxel (1) · Polyamines (1) · Pregabalin (1) · Taxes (1) · ixabepilone (1)
Alliance for Clinical Trials in Oncology (2) · Ain Shams University (1) · Gynecologic Oncology Group (1) · Mayo Clinic (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (1) · SWOG Cancer Research Network (1) · University Hospital, Clermont-Ferrand (1)
United States (5) · Puerto Rico (2) · Canada (1) · Colombia (1) · Dominican Republic (1) · Egypt (1) · France (1) · India (1) · Peru (1) · Poland (1) · South Africa (1) · Thailand (1)
Charles Loprinzi (2) · Charles L. Loprinzi, MD (1) · David Kushner (1) · Laurence H. Baker, DO, FACOI (1)
PMID 23733756, PMID 24297951, PMID 24907403, PMID 25833669, PMID 34176021
P30CA015083 (1), U10CA037404 (1), U10CA037429 (1), U10CA101165 (1)