15 completed, 9 unknown, 4 recruiting, 3 terminated. 35 Phase 3, 8 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 35 | Completed 15, Unknown 9, Recruiting 4, Terminated 3, Withdrawn 3, Active not recruiting 1 |
| Phase 2 | 8 | Completed 4, Recruiting 1, Terminated 1, Unknown 1, Withdrawn 1 |
Follow Nephrolithiasis: new trials by email Literature Review of Nephrolithiasis trials Research Report on Nephrolithiasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The GranStone Trial empagliflozin (Jardiance) 25 mg, Losartan 100 mg - Paraffinoma, Granuloma, Foreign-Body | Phase 2 / Phase 3 | Recruiting | Martin Blomberg Jensen | 100 | 2026-10-20 | 2026-11-10 |
| Trial to Assess the Efficacy of EMPAgliflozin and Personalized Dietary Counseling for Kidney STONE Prevention Empagliflozin 10 MG, Placebo, Personalized dietary counseling - Kidney Stone, Nephrolithiasis | Phase 3 | Recruiting | Insel Gruppe AG, University Hospital Bern | 400 | 2026-07-02 | 2026-10-23 |
| Spinal Morphine or Intravenous Lidocaine in Robot-assisted Upper Urologic Surgery spinal analgesia with morphine and bupivacaine, lidocaine infusion - Other Specified Disorders of Kidney and Ureter, Benign Neoplasm of Ureter | Phase 3 | Recruiting | Hans Bahlmann | 220 | 2024-04-09 | 2026-02-05 |
| Impact of Forced Diuresis on the Residual Fragment Rate After Flexible Ureteroscopy for Destruction of Kidney Stones With Laser Furosemide 40 mg - Kidney Stone | Phase 3 | Recruiting | University Hospital, Tours | 374 | 2024-01-04 | 2026-11-09 |
| Flexible Mini Percutaneous Nephrolithotomy Vs Retrograde Intra-renal Surgery flexible mini percutaneous nephrolithotomy, Retrograde intrarenal surgery - Renal Stone | Phase 2 / Phase 3 | Completed | Ain Shams University | 130 | 2024-01-01 | 2024-10-29 |
| Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1 Encaleret, Standard of Care - Autosomal Dominant Hypocalcemia (ADH) | Phase 3 | Active not recruiting | Calcilytix Therapeutics, Inc., a BridgeBio company | 67 | 2023-01-06 | 2026-07-29 |
| Enhanced Versus Extended Preoperative Antibiotic Prophylaxis Regimens for Retrograde Intrarenal Surgery in High Infectious Risk Patients Enhanced regimen, Extended regimen - Renal Stone | Phase 3 | Unknown | Mansoura University | 280 | 2022-05-01 | 2022-11-14 |
| Tamsulosin Assisted Ureteral Access Sheath Insertion Tamsulosin - Renal Stone, Retrograde Intrarenal Surgery | Phase 3 | Completed | Sengkang General Hospital | 110 | 2022-03-01 | 2026-09-30 |
| Ultra-Mini Versus Standard Percutaneous Nephrolithotomy For Management Of Renal Calculi. A Randomized Controlled Trial. percutaneous nephrolithotomy, ultra-mini percutaneous nephrolithotomy - Stone, Kidney | Phase 3 | Unknown | Ain Shams University | 60 | 2021-02-28 | 2021-02-21 |
| Holmium Vs Trilogy Kidney Stones GUY's 1-2 Fragmentation of calculi with 100 W Holmium laser or LithoClast Trilogy EMS and 1.5 mm x 440 mm probe, according to randomization. - Kidney Stone, Kidney Calculi | Phase 3 | Unknown | Hospital Regional de Alta Especialidad del Bajio | 116 | 2020-09-30 | 2020-09-22 |
| Effect of Furosemide on ESWL Outcomes for Renal and Ureteral Calculi Furosemide 40 mg, Conventional Treatment - Urolithiasis, Nephrolithiasis | Phase 3 | Unknown | Shiraz University of Medical Sciences | 500 | 2020-07-01 | 2022-03-08 |
| Perioperative Pregabalin in Ureteroscopy Pregabalin 300mg, Placebo oral tablet - Kidney Stone, Pain, Postoperative | Phase 2 / Phase 3 | Completed | University of Missouri-Columbia | 118 | 2020-06-01 | 2025-11-12 |
| Mirabegron And Ureteral Stent-related Pain (MAP) Trial Mirabegron 50 MG, Placebo oral tablet - Nephrolithiasis | Phase 3 | Unknown | Unity Health Toronto | 142 | 2020-02-03 | 2020-02-26 |
| Establishing the Safety and Efficacy of Reloxaliase in Patients With Enteric Hyperoxaluria Reloxaliase, Placebo - Enteric Hyperoxaluria | Phase 3 | Terminated | Allena Pharmaceuticals | 92 | 2019-08-26 | 2022-06-10 |
| Supine Percutaneous Nephrolithotomy percutaneous nephrolithotomy (supine position), percutaneous nephrolithotomy ( prone position) - Renal Stone | Phase 2 / Phase 3 | Completed | Ain Shams University | 70 | 2019-06-01 | 2022-07-14 |
| Perioperative Pregabalin in Ureteroscopy: a Pilot Pregabalin 300mg - Nephrolithiasis, Urolithiasis | Phase 3 | Completed | University of Missouri-Columbia | 10 | 2019-04-01 | 2021-04-19 |
| Pain Outcomes of Non-opioid vs. Opioid Analgesia for Kidney Stone Surgery. Ketorolac Oral Tablet [Toradol], Acetaminophen, Oxycodone Acetaminophen - Nephrolithiasis | Phase 3 | Completed | Montefiore Medical Center | 119 | 2018-07-27 | 2023-12-18 |
| Evaluate ALLN-177 in Patients With Enteric Hyperoxaluria ALLN-177, Placebo - Enteric Hyperoxaluria | Phase 3 | Completed | Allena Pharmaceuticals | 115 | 2018-05-21 | 2020-02-27 |
| Lanthanum Carbonate (Fosrenol®) to Reduce Oxalate Excretion in Patients With Secondary Hyperoxaluria and Nephrolithiasis Lanthanum Carbonate - Secondary Hyperoxaluria, Nephrolithiasis | Phase 3 | Completed | Universitair Ziekenhuis Brussel | 54 | 2017-08-18 | 2026-08-10 |
| Efficacy of Liposomal Bupivacaine for Pain Control After Percutaneous Nephrostolithotomy liposomal bupivicaine, Bupivacaine, Saline Solution - Renal Calculi, Postoperative Pain | Phase 3 | Withdrawn | Northwell Health | 2017-08-08 | 2017-08-28 |
Showing 20 of 35. Sign in to see all of them.
Kidney Calculi (20) · Urolithiasis (4) · Hypercalciuria (3) · Hyperoxaluria (3) · Nephrocalcinosis (3) · Pain, Postoperative (3) · Hypercalcemia (2) · Acute Pain (1) · Behavior, Addictive (1) · Calcium Metabolism Disorders (1) · Colic (1) · Dent Disease (1) · Glomerulonephritis (1) · Granuloma, Foreign-Body (1)
Female Urogenital Diseases (35) · Female Urogenital Diseases and Pregnancy Complications (35) · Male Urogenital Diseases (35) · Kidney Diseases (34) · Urogenital Diseases (34) · Urologic Diseases (34) · Urolithiasis (31) · Pathological Conditions, Signs and Symptoms (26) · Calculi (21) · Pathological Conditions, Anatomical (21) · Urinary Calculi (20) · Pathologic Processes (7) · Signs and Symptoms (7) · Neurologic Manifestations (4)
Tamsulosin (3) · Bupivacaine (2) · Furosemide (2) · Hydrochlorothiazide (2) · Morphine (2) · Nephrolithotomy, Percutaneous (2) · Pregabalin (2) · alfuzosin (2) · empagliflozin (2) · oxalate decarboxylase (2) · reloxaliase (2) · silodosin (2) · Acetaminophen (1) · Adrenocorticotropic Hormone (1) · Ampicillin (1)
Ain Shams University (3) · Allena Pharmaceuticals (2) · Insel Gruppe AG, University Hospital Bern (2) · Northwell Health (2) · University of Missouri-Columbia (2) · Advance Shockwave Technology GmbH (1) · Albany Medical College (1) · Albert Einstein Healthcare Network (1) · Assistance Publique - Hôpitaux de Paris (1) · Brigham and Women's Hospital (1) · Calcilytix Therapeutics, Inc., a BridgeBio company (1) · Catalysis SL (1) · Centre Hospitalier Departemental Vendee (1) · Fredericia Hosptial (1) · Hans Bahlmann (1)
United States (14) · France (7) · Canada (4) · Denmark (4) · Egypt (4) · Italy (4) · Germany (3) · Switzerland (3) · United Kingdom (3) · Belgium (2) · Brazil (2) · Mexico (2) · Spain (2) · Australia (1) · Austria (1)
Katie Murray, DO (2) · Amr A Elsawy (1) · Annamaria Kausz, MD MS (1) · Brian K. Auge, M.D. (1) · Charles Y. C. Pak (1) · Christian Tielemans, MD, PhD (1) · Daniel Fuster (1) · Daniel Fuster, Prof MD (1) · Dariush Irani, MD (1) · David Clark, MD (1) · David M Hoenig, md (1) · Ehab Nour (1)
PMID 10360498, PMID 18976849, PMID 24707884, PMID 27758119, PMID 28608192, PMID 29649900, PMID 30526528, PMID 30961854, PMID 31177306, PMID 31588790, PMID 36856614, PMID 37578113, PMID 38319254, PMID 38965611, PMID 39028573, PMID 40210001, PMID 41460253, PMID 42091145
2016 (1), 2018 (1), 2023 (1)