531 completed, 291 unknown, 283 recruiting, 184 terminated. 1659 Early Phase 1.
Follow Neoplasms: new trials by email Literature Review of Neoplasms trials Research Report on Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Monitoring Breast Cancer Immunotherapy Treatment With Advanced Positron Emission Tomography Magnetic Resonance Imaging (PET/MRI) [18F]FMISO-PET with contrast-enhanced MRI - Triple Negative Breast Cancer | Early Phase 1 | Recruiting | University of Alabama at Birmingham | 20 | 2027-06-01 | 2026-08-17 |
| A Clinical Study to Investigate the Safety and Efficacy of Off-the-Shelf iNKT Cell Injection Targeting CD33/CD70 in Adult Patients With Relapsed/Refractory Acute Myeloid Leukemia GT737 Injection - Relapsed/Refractory Acute Myeloid Leukemia (AML) | Early Phase 1 | Not yet recruiting | Grit Biotechnology | 36 | 2027-05-01 | 2026-09-11 |
| MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors [F-18]MeFAMP PET - Healthy Volunteers, Recurrent Glioma | Early Phase 1 | Not yet recruiting | University of Alabama at Birmingham | 28 | 2027-04-01 | 2026-08-20 |
| Oral Gallium Maltolate for Recurrent Glioblastoma Gallium Maltolate, Surgical Intervention - Glioblastoma | Early Phase 1 | Not yet recruiting | Medical College of Wisconsin | 8 | 2027-03-01 | 2026-09-23 |
| Biomarker-guided RAdiation-deferring Treatment in Younger GBM Patients - Pilot Study Larotrectinib, Cadonilimab, Plixorafenib - IDH Wildtype Glioblastoma, Glioblastoma (GBM) | Early Phase 1 | Not yet recruiting | Olivia Newton-John Cancer Research Institute | 12 | 2027-03-01 | 2026-10-30 |
| A Pilot Study to Examine the Efficacy and Tolerability of Sirolimus on Epidermal Nevi Lesions in Patients 6 Years Old and Above. sirolimus topical gel 0.2% - Epidermal Nevi | Early Phase 1 | Not yet recruiting | Northwestern University | 14 | 2027-02-01 | 2026-11-09 |
| Characterization of the Microbiome in Cutaneous T Cell Lymphoma Skin Lesions Before and After Use of APR-TD011® (RLF-TD011®) Spray Solution APR-TD011 (RLF-TD011) - Cutaneous T Cell Lymphoma | Early Phase 1 | Not yet recruiting | Northwestern University | 30 | 2027-01-01 | 2026-05-01 |
| NK521 in the Treatment of Advanced Solid Tumors NK521 Cell Injection - Hepatocellular Carcinoma (HCC), Ovarian Cancer | Early Phase 1 | Not yet recruiting | Base Therapeutics (Shanghai) Co., Ltd. | 18 | 2027-01-01 | 2026-09-30 |
| Pilot Study Evaluating Tumor Microenvironment Interaction in Solid Tumor Patients 68Ga-FAPI-46 - Solid Tumor Cancer, Solid Tumor Malignancy | Early Phase 1 | Withdrawn | Eben Rosenthal | 2027-01-01 | 2026-01-21 | |
| Dose-Escalation/Expansion Study of iMagic in Relapsed/Refractory Hematologic Malignancies iMagic Injection (IMV101), iMagic Injection (IMV102) - Relapsed/Refractory Hematologic Malignancies | Early Phase 1 | Not yet recruiting | Suzhou Immunofoco Biotechnology Co., Ltd | 30 | 2026-12-10 | 2026-11-04 |
| Window of Opportunity Study of Lixumistat in Patients With Newly Diagnosed Glioblastoma Lixumistat - Cohort 1, Lixumistat - Cohort 2 - Glioblastoma | Early Phase 1 | Recruiting | Macarena De La Fuente, MD | 10 | 2026-12-01 | 2026-10-20 |
| A Clinical Study to Evaluate the Safety and Efficacy of GT802 Injection in the Treatment of Refractory Generalized Myasthenia Gravis GT802 Injection - Generalized Myasthenia Gravis (gMG) | Early Phase 1 | Not yet recruiting | Daishi Tian | 12 | 2026-12-01 | 2026-11-05 |
| Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG 18F-Fluciclovine - Glioma, Low-grade Glioma | Early Phase 1 | Recruiting | Children's Hospital of Philadelphia | 30 | 2026-11-29 | 2026-09-22 |
| Safety and Feasibility of First-line Avutometinib and Defactinib in Patients With Newly Diagnosed High-grade Gliomas avutometinib and defactinib for 3 weeks on/1 week off, MGMT-unmethylated GBM with Radiation - MGMT-unmethylated Glioblastoma (GBM), IDH Wildtype Glioblastoma | Early Phase 1 | Not yet recruiting | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 22 | 2026-11-10 | 2026-08-26 |
| A Study of CA9-Targeted CAR Macrophage Therapy in Advanced Clear Cell Renal Cell Carcinoma CM-BA-9 - Clear Cell Renal Cell Carcinoma | Early Phase 1 | Not yet recruiting | Liangyou Gu | 6 | 2026-11-01 | 2026-10-08 |
| Multiparametric Metabolic and Hypoxic PET/MRI Imaging Substudy in Gliomas [18F]FMISO-PET with contrast-enhanced MRI - Glioma | Early Phase 1 | Not yet recruiting | University of Alabama at Birmingham | 20 | 2026-11-01 | 2026-10-30 |
| Asciminib With or Without Sildenafil for Brain Tumors Asciminib, Sildenafil, Surgical resection or biopsy - Brain Tumor | Early Phase 1 | Not yet recruiting | Washington University School of Medicine | 12 | 2026-10-31 | 2026-09-11 |
| Implantable Microdevices for in Situ Evaluation of Drug Responses in Lung Cancer Implantable Micro- drug delivery Microdevice (IMD) - Lung Cancer, Mesothelioma | Early Phase 1 | Not yet recruiting | Oliver Jonas | 20 | 2026-10-30 | 2026-10-23 |
| Safety and Diagnostic Efficacy of 177Lu-AF03 in Patients With Solid Tumors 177Lu-AF03 - Malignant Solid Tumors, Neoplasms | Early Phase 1 | Not yet recruiting | Yong He | 8 | 2026-10-20 | 2026-10-19 |
| GLP-1 RA Plus SOC Treatment in First-line, Metastatic Pancreatic, Colorectal, or Hepatocellular Cancer GLP1-RA (semaglutide) - Pancreatic Cancer, Colorectal Cancer | Early Phase 1 | Recruiting | University of Arizona | 30 | 2026-10-10 | 2026-09-18 |
Showing 20 of 1659. Sign in to see all of them.
Breast Neoplasms (185) · Prostatic Neoplasms (107) · Glioblastoma (88) · Multiple Myeloma (87) · Pancreatic Neoplasms (81) · Glioma (70) · Brain Neoplasms (62) · Lung Neoplasms (60) · Carcinoma, Non-Small-Cell Lung (59) · Head and Neck Neoplasms (58) · Colorectal Neoplasms (56) · Melanoma (56) · Leukemia, Myeloid, Acute (54) · Carcinoma, Hepatocellular (53)
Neoplasms by Site (1011) · Neoplasms by Histologic Type (844) · Neoplasms, Glandular and Epithelial (397) · Hemic and Lymphatic Diseases (360) · Immune System Diseases (297) · Urogenital Diseases (295) · Immunoproliferative Disorders (279) · Lymphoproliferative Disorders (273) · Digestive System Diseases (272) · Skin and Connective Tissue Diseases (268) · Skin Diseases (264) · Neoplasms, Nerve Tissue (258) · Digestive System Neoplasms (257) · Neuroectodermal Tumors (253)
Magnetic Resonance Spectroscopy (59) · Cyclophosphamide (45) · pembrolizumab (34) · Radiotherapy (29) · fludarabine (28) · Nivolumab (27) · Biopsy (25) · Fluorodeoxyglucose F18 (21) · Metformin (21) · Bevacizumab (19) · Specimen Handling (18) · Temozolomide (18) · Radiosurgery (17) · Cisplatin (16) · Dexamethasone (16)
M.D. Anderson Cancer Center (50) · Mayo Clinic (48) · Peking Union Medical College Hospital (37) · Memorial Sloan Kettering Cancer Center (28) · Washington University School of Medicine (28) · Zhejiang University (28) · Case Comprehensive Cancer Center (24) · H. Lee Moffitt Cancer Center and Research Institute (23) · Northwestern University (20) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (20) · Abramson Cancer Center at Penn Medicine (19) · First Affiliated Hospital of Fujian Medical University (18) · University of Virginia (18) · National Cancer Institute (NCI) (16) · University of Alabama at Birmingham (16)
United States (888) · China (448) · Canada (30) · Australia (17) · Spain (17) · France (15) · United Kingdom (11) · Netherlands (10) · Denmark (9) · Sweden (9) · Egypt (8) · Switzerland (8) · Germany (7) · Italy (7) · Taiwan (7)
Nader Sanai, MD (13) · Weibing Miao, MD (10) · Chunjing Yu (7) · Christine Burt Solorzano, MD (5) · Fang Li, MD (5) · Fang Liu, MD, PhD (5) · He Huang, MD (5) · Hongyu Zhang, MD, PhD (5) · Zhaohui Zhu (5) · Nadia N. Laack, M.D. (4) · Zhaohui Zhu, MD (4) · Zhaohui Zhu, MD,PHD (4) · Farrokh Dehdashti, M.D. (3) · Frank Lieberman, MD (3) · Jeremie Calais, MD (3)
PMID 37192741, PMID 26424652, PMID 30207593, PMID 32379297, PMID 34081125, PMID 39501801, PMID 40540129, PMID 42294856, PMID 12855309, PMID 14688713, PMID 14871955, PMID 16601950, PMID 16648043, PMID 16942948, PMID 17197840, PMID 17449766, PMID 17701250, PMID 17921033, PMID 18042692, PMID 18298885, PMID 18682712, PMID 19008992, PMID 19095497, PMID 19366446, PMID 19525452, PMID 19660720, PMID 19880495, PMID 19903919, PMID 19917951, PMID 20518581, PMID 20632579, PMID 20671118, PMID 20948452, PMID 21042103, PMID 21212426, PMID 21233180, PMID 21252315, PMID 21324454, PMID 21359953, PMID 21544866, PMID 21692253, PMID 21831090, PMID 21849404, PMID 21985945, PMID 22082029, PMID 22154591, PMID 22253412, PMID 22321518, PMID 22499613, PMID 22719020
P30CA015083 (13), P30CA012197 (9), P30CA016672 (9), P30CA138292 (9), P30CA033572 (7), P30CA043703 (7), 2019 (6), P30CA060553 (6), P30CA072720 (6), 2018 (4), P30CA068485 (4), ZIAEB000073 (4), 2015 (3), 2016 (3), 2023 (3)