169 completed. 169 Phase 3, 16 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 169 | Completed 169 |
| Phase 2 | 16 | Completed 16 |
Follow Neoplasm Metastasis: new trials by email Literature Review of Neoplasm Metastasis trials Research Report on Neoplasm Metastasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study Evaluating the Benefit of Adding Ipilimumab to the Combination of Atezolizumab and Bevacizumab in Patients With Hepatocellular Carcinoma Receiving First-line Systemic Therapy Ipilimumab Injection, Atezolizumab Injection, Bevacizumab - HCC - Hepatocellular Carcinoma, Metastatic Cancer | Phase 2 / Phase 3 | Completed | Federation Francophone de Cancerologie Digestive | 229 | 2023-03-09 | 2026-03-09 |
| Trilaciclib, a CDK 4/6 Inhibitor, in Patients Receiving Gemcitabine and Carboplatin for Metastatic Triple-Negative Breast Cancer (TNBC) Trilaciclib, Placebo, Gemcitabine - TNBC - Triple-Negative Breast Cancer, Breast Cancer | Phase 3 | Completed | G1 Therapeutics, Inc. | 194 | 2021-05-14 | 2024-08-01 |
| TAVT-45 (Abiraterone Acetate) Granules in Patients With Prostate Cancer TAVT-45, Zytiga, Prednisone - Metastatic Castration-resistant Prostate Cancer, Metastatic Castration-sensitive Prostate Cancer | Phase 3 | Completed | Tavanta Therapeutics | 107 | 2021-05-05 | 2024-01-16 |
| RegoNivo vs Standard of Care Chemotherapy in AGOC Regorafenib, Nivolumab, Docetaxel - Gastro-Oesophageal Cancer | Phase 3 | Completed | Australasian Gastro-Intestinal Trials Group | 462 | 2021-05-05 | 2026-06-10 |
| Platinum-Based Chemotherapy With/Without INCMGA00012, an Anti-PD-1 Antibody, in Non-Small Cell Lung Cancer Retifanlimab, Placebo, Pemetrexed - Metastatic Squamous Non-Small Cell Lung Cancer, Metastatic Nonsquamous Non-Small Cell Lung Cancer | Phase 3 | Completed | Incyte Corporation | 583 | 2020-09-11 | 2026-07-06 |
| Postoperative Pain, Why Still in Hospital and DAOH Following TORS for SCCUP & OSAS Dexamethasone, Placebo - Analgesia, Surgery | Phase 3 | Completed | Copenhagen University Hospital, Rigshospitalet | 18 | 2020-08-18 | 2023-03-16 |
| 11C-Metomidate PET/CT for Endocrine Hypertension and Characterisation of Adrenal Tumours 11C-Metomidate PET/CT imaging at Clinical Imaging Research Centre - Primary Aldosteronism Due to Aldosterone Producing Adenoma, Primary Aldosteronism | Phase 2 / Phase 3 | Completed | Changi General Hospital | 97 | 2019-12-30 | 2026-10-26 |
| Molecular Profiling of Advanced Soft-tissue Sarcomas Nilotinib, Ceritinib, Capmatinib - Soft Tissue Sarcoma | Phase 3 | Completed | Institut National de la Santé Et de la Recherche Médicale, France | 603 | 2019-10-19 | 2026-04-29 |
| 99mTc-3PRGD2 SPECT/CT for Integrin Imaging of Lung Cancer 99mTc-3PRGD2 injection - Lung Cancer, Lymph Node Metastasis | Phase 3 | Completed | RDO Pharm. | 409 | 2019-10-12 | 2024-07-01 |
| A Study to Evaluate SHR-1210 in Combination With Apatinib as First-Line Therapy in Patients With Advanced HCC SHR-1210, Apatinib, Sorafenib - Locally Advanced or Metastatic and Unresectable HCC | Phase 3 | Completed | Jiangsu HengRui Medicine Co., Ltd. | 543 | 2019-06-10 | 2024-02-06 |
| Trastuzumab Deruxtecan (DS-8201a) Versus Investigator's Choice for HER2-low Breast Cancer That Has Spread or Cannot be Surgically Removed [DESTINY-Breast04] Trastuzumab deruxtecan (DS-8201a), Capecitabine, Eribulin - Breast Cancer | Phase 3 | Completed | Daiichi Sankyo | 557 | 2018-12-27 | 2026-09-28 |
| A Study of Tislelizumab (BGB-A317) Versus Chemotherapy as Second Line Treatment in Participants With Advanced Esophageal Squamous Cell Carcinoma Tislelizumab, Paclitaxel, Docetaxel - Esophageal Squamous Cell Carcinoma (ESCC) | Phase 3 | Completed | BeiGene | 512 | 2018-01-26 | 2024-10-26 |
| Tissue-of-origin Directing Therapy in Patients With Cancer of Unknown Primary tissue-of-origin (ORIGIN-PanCA○R) profiling - Cancer of Unknown Primary Site | Phase 3 | Completed | Fudan University | 182 | 2017-09-18 | 2022-01-24 |
| Study of Cemiplimab in Adults With Cervical Cancer Cemiplimab, Investigator Choice (IC) Chemotherapy - Squamous Cell Carcinoma (SCC), Recurrent or Metastatic, Platinum-refractory Cervical Cancer | Phase 3 | Completed | Regeneron Pharmaceuticals | 608 | 2017-09-05 | 2025-04-08 |
| Apixaban in Preventing Secondary Cancer Related Venous Thrombosis in Cancer Patients Who Have Completed Anticoagulation Therapy Apixaban - Cerebral Vein Thrombosis, Deep Vein Thrombosis | Phase 3 | Completed | Academic and Community Cancer Research United | 370 | 2017-07-14 | 2025-05-18 |
| Optimal Sequencing of Treatment Options for Poor Risk mCRPC Previously Treated With Docetaxel Cabazitaxel, Abiraterone, Enzalutamide - Prostate Cancer Metastatic, Metastasis | Phase 2 / Phase 3 | Completed | The Netherlands Cancer Institute | 100 | 2017-05-07 | 2022-04-15 |
| Study Comparing Rovalpituzumab Tesirine Versus Topotecan in Subjects With Advanced or Metastatic Small Cell Lung Cancer With High Levels of Delta-like Protein 3 (DLL3) and Who Have First Disease Progression During or Following Front-line Platinum-based Chemotherapy (TAHOE) Rovalpituzumab tesirine, Topotecan, Dexamethasone - Small Cell Lung Cancer | Phase 3 | Completed | AbbVie | 444 | 2017-04-11 | 2021-02-23 |
| A Study to Evaluate Rivoceranib Plus Best Supportive Care Compared to Placebo Plus Best Supportive Care in Participants With Gastric Cancer Rivoceranib, Placebo - Gastric Cancer, Gastric Adenocarcinoma | Phase 3 | Completed | Elevar Therapeutics | 460 | 2017-03-14 | 2022-07-08 |
| A Study of Etirinotecan Pegol (NKTR-102) Versus Treatment of Physician's Choice (TPC) in Patients With Metastatic Breast Cancer Who Have Stable Brain Metastases and Have Been Previously Treated With an Anthracycline, a Taxane, and Capecitabine NKTR-102, Eribulin, Ixabepilone - Metastasis, Breast Cancer | Phase 3 | Completed | Nektar Therapeutics | 178 | 2016-11-01 | 2023-04-14 |
| A Study of Trifluridine/Tipiracil (Also Known as S 95005 or TAS-102) in Patients With a Pretreated Colorectal Cancer That Has Spread (Metastatic). Trifluridine/Tipiracil hydrochloride (S95005) - Metastatic Colorectal Cancer | Phase 3 | Completed | Institut de Recherches Internationales Servier | 907 | 2016-10-18 | 2024-07-25 |
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Breast Neoplasms (29) · Colorectal Neoplasms (24) · Neoplasms (21) · Prostatic Neoplasms (16) · Brain Neoplasms (15) · Carcinoma, Non-Small-Cell Lung (12) · Melanoma (8) · Pain (8) · Lung Neoplasms (7) · Stomach Neoplasms (7) · Neoplasms, Unknown Primary (6) · Carcinoma (5) · Carcinoma, Renal Cell (5) · Colonic Neoplasms (5)
Pathologic Processes (169) · Pathological Conditions, Signs and Symptoms (169) · Neoplastic Processes (168) · Neoplasms (148) · Neoplasms by Site (139) · Digestive System Diseases (43) · Digestive System Neoplasms (40) · Neoplasms by Histologic Type (39) · Skin and Connective Tissue Diseases (39) · Skin Diseases (36) · Gastrointestinal Diseases (35) · Gastrointestinal Neoplasms (33) · Breast Diseases (28) · Urogenital Diseases (26) · Intestinal Diseases (25)
Capecitabine (12) · Gemcitabine (12) · Paclitaxel (12) · Docetaxel (11) · Fluorouracil (11) · Irinotecan (10) · Leucovorin (10) · Radiotherapy (10) · Bevacizumab (8) · Oxaliplatin (8) · Carboplatin (6) · Radiosurgery (6) · Zoledronic Acid (6) · Surgical Procedures, Operative (5) · Cisplatin (4)
Alliance for Clinical Trials in Oncology (9) · Sanofi (8) · Pfizer (6) · AstraZeneca (5) · Novartis Pharmaceuticals (5) · Radiation Therapy Oncology Group (5) · European Organisation for Research and Treatment of Cancer - EORTC (4) · Samsung Medical Center (4) · AbbVie (3) · Amgen (3) · Bristol-Myers Squibb (3) · Genentech, Inc. (3) · Academic and Community Cancer Research United (2) · Celgene Corporation (2) · Eli Lilly and Company (2)
United States (93) · France (58) · Italy (57) · United Kingdom (54) · Germany (52) · Spain (51) · Canada (50) · Poland (47) · Russia (45) · Australia (41) · Belgium (38) · South Korea (38) · Netherlands (36) · Hungary (33) · Brazil (32)
Paul D. Brown, MD (3) · A.N. Van Geel, MD (1) · Alan W Craft, Prof Sir MD (1) · Aminah Jatoi, MD (1) · Andreas Maetzel, MD, PhD (1) · Anthony Asher, MD, FACS (1)
PMID 17686822, PMID 30679026, PMID 31378656, PMID 33270906, PMID 36606664, PMID 10493478, PMID 11913730, PMID 12782596, PMID 14572748, PMID 15158627, PMID 15764775, PMID 15928300, PMID 16062084, PMID 16314619, PMID 16505413, PMID 16814950, PMID 17329192, PMID 17401015, PMID 17554116, PMID 17671254, PMID 17968020, PMID 18182660, PMID 18188694, PMID 18205003, PMID 18316791, PMID 18406884, PMID 18588404, PMID 18776057, PMID 18988231, PMID 19064978, PMID 19144677, PMID 19443658, PMID 19632065, PMID 19726226, PMID 20164695, PMID 20525992, PMID 20736298, PMID 20881001, PMID 21059637, PMID 21128114, PMID 21459795, PMID 21592754, PMID 21742485, PMID 21903473, PMID 21937232, PMID 21989330, PMID 22013950, PMID 22649106, PMID 22694829, PMID 22949147
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