Neoadjuvant Therapy: Clinical Trials

24 trials for Neoadjuvant Therapy, newest first

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8 recruiting, 6 not yet recruiting, 4 unknown, 3 active not recruiting. 24 Not applicable.

By phase and status

PhaseTrialsStatus
Not applicable24Recruiting 8, Not yet recruiting 6, Unknown 4, Active not recruiting 3, Completed 2, Enrolling by invitation 1

Follow Neoadjuvant Therapy: new trials by email Literature Review of Neoadjuvant Therapy trials Research Report on Neoadjuvant Therapy

Trials (filtered) newest first · largest first

All 24 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Adaptive Neoadjuvant Therapy for Esophageal Cancer
Neoadjuvant concurrent chemoradiotherapy - Esophageal Carcinoma, Neoadjuvant Therapy
Not applicableEnrolling by invitationCancer Hospital Chinese Academy of Medical Science, Shenzhen Center432028-03-012025-05-25
Impact of Routine Electronic Patient-Reported Outcome (ePRO)Symptom Monitoring During Neoadjuvant Therapy in Patients withPancreatic Adenocarcinoma on Patient Experience and ClinicalOutcomes: A Prospective Pre-Post Implementation Study
Standard of Care - ePRO, Symptom Monitoring
Not applicableNot yet recruitingM.D. Anderson Cancer Center2002027-02-212026-09-21
Neoadjuvant Iruplinalkib and Bevacizumab in ALK-positive NSCLC: A Phase II Single-arm Trial
Bevacizumab combined with iruplinalkib as neoadjuvant therapy in ALK-positive NSCLC: - ALK, NSCLC
Not applicableNot yet recruitingShanghai Pulmonary Hospital, Shanghai, China402026-09-152026-10-13
MRD-Guided Postoperative Surveillance and Adaptive Treatment for Resectable Lung Cancer
Adaptive therapy of de-escalation and escalation based on MRD testing and pathological response - Lung Neoplasms, Neoadjuvant Therapy
Not applicableRecruitingPeking University People's Hospital1002026-08-122026-10-26
Oral Paclitaxel as Neoadjuvant Therapy in Elderly NSCLC: A Phase II Trial
Paclitaxel Oral Solution - Non-Small-Cell Lung Cancer, Neoadjuvant Therapy
Not applicableNot yet recruitingShanghai Pulmonary Hospital, Shanghai, China752026-06-082026-05-20
Digital Mind-Body Therapy for Neoadjuvant Breast Cancer
DMBT - Neoadjuvant Therapy
Not applicableRecruitingFudan University662026-03-252026-04-21
Family-Supervised Prehabilitation to Reduce Postoperative Complications After Neoadjuvant Chemotherapy in Gastric Cancer
Family-supervised Multimodal Prehabilitation, Standard Care - Stomach Neoplasms, Neoadjuvant Therapy
Not applicableNot yet recruitingThe Affiliated Hospital of Qingdao University902025-09-202025-09-19
Simple Surgical Glove Compression to Prevent Chemotherapy-Induced Peripheral Neuropathy
Simple Surgical Glove Compression Technique - Breast Cancer, Chemotherapy Induced Peripheral Neuropathy (CIPN)
Not applicableNot yet recruitingJinsong Lu442025-09-152025-09-12
Study of Neoadjuvant Cemiplimab and Dupilumab in Early-Stage Non-Small Cell Lung Cancer
Cemiplimab, Dupilumab - Non-Small Cell Lung Cancer, Immunotherapy
Not applicableRecruitingCentre hospitalier de l'Université de Montréal (CHUM)242025-08-192026-08-17
Reduce Sedentary Behavior During Cancer Treatment - the RedSedCan Study
Digital self-management program - Breast Cancer, Colorectal Cancer (CRC)
Not applicableRecruitingMälardalen University2102025-03-012026-10-01
Question Prompt List in Breast Cancer Patients Planned for Neoadjuvant Chemotherapy
Question prompt list - Breast Cancer Early Stage Breast Cancer (Stage 1-3), Neoadjuvant Therapy
Not applicableRecruitingRegion Örebro County2182025-03-012025-04-20
Application of Targeted Axillary Lymph Node Resection in Axillary Surgery After Neoadjuvant Chemotherapy for Breast Cancer: an Open-label, Multicenter Study
carbon suspension - Breast Cancer Surgery, Neoadjuvant Therapy
Not applicableActive not recruitingFujian Medical University Union Hospital1752024-12-092025-06-22
Effect of Vitamin D Supplementation on the Efficacy and Adverse Effects of Neoadjuvant Therapy in Patients with Breast Cancer
Neoadjuvant therapy + vitamin D2, Neoadjuvant therapy - Vitamin D, Neoadjuvant Therapy
Not applicableRecruitingJiuda Zhao1402024-10-182025-01-17
Living Donor Liver Transplantation for Intrahepatic Cholangiocarcinoma
Living donor liver transplantation - Living Donor Liver Transplantation, Liver Transplantation
Not applicableNot yet recruitingJena University Hospital62024-09-012024-08-06
The Clinical Efficacy of Drug Sensitive Neoadjuvant Chemotherapy Based on Organoid Versus Traditional Neoadjuvant Chemotherapy in Advanced Rectal Cancer
standard long-term therapy, FOLFOX and standard long-term radiotherapy, FOLFIRI and standard long-term radiotherapy - Neoadjuvant Therapy
Not applicableUnknownShanghai Minimally Invasive Surgery Center1922023-01-012022-04-28
Reducing Excision Margins After Neoadjuvant Chemoimmunotherapy for HPV Negative Resectable Locally Advanced HNSCC
Reducing Excision Margins - Squamous Cell Carcinoma of Head and Neck, Neoadjuvant Therapy
Not applicableActive not recruitingUnion Hospital, Tongji Medical College, Huazhong University of Science and Technology542022-06-222022-07-15
Contrast-enhanced Ultrasonography Combined With Blue Dye as Dual-tracer for Sentinel Lymph Node Biopsy
CEUS, blue dye - Breast Neoplasms, Neoadjuvant Therapy
Not applicableUnknownFirst Affiliated Hospital, Sun Yat-Sen University3502021-06-152021-06-21
Clinical Application of Multi-modal Sentinel Lymph Node Staining Method in Breast Cancer Patients After Neoadjuvant Chemotherapy
Radioactive Isotope (RI) Mapping, Indocyanine Green Fluorescence (ICG-F) Mapping, Vital Dye Mapping - Sentinel Lymph Node Biopsy, Neoadjuvant Therapy
Not applicableCompletedNational Cancer Center, Korea3482021-05-042025-03-13
Multimodal Prehabilitation During Chemotherapy in Patients With Colorectal Liver Metastases
Physical Prehabilitation - Prehabilitation, Neoadjuvant Therapy
Not applicableRecruitingInstitut Investigacio Sanitaria Pere Virgili842021-02-012024-07-01
Multi-points and Full-thickness Biopsy in the Diagnosis of cCR After Neoadjuvant Therapy for Rectal Cancer
multi-points and full-thickness Biopsy, traditional cCR - Rectal Cancer, Neoadjuvant Therapy
Not applicableRecruitingBeijing Chao Yang Hospital2602021-01-012023-02-21

Showing 20 of 24. Sign in to see all of them.

Narrower conditions

Breast Neoplasms (9)  ·  Carcinoma, Non-Small-Cell Lung (2)  ·  Cholangiocarcinoma (1)  ·  Colorectal Neoplasms (1)  ·  Esophageal Neoplasms (1)  ·  Lung Neoplasms (1)  ·  Margins of Excision (1)  ·  Neoplasm Metastasis (1)  ·  Neoplasm, Residual (1)  ·  Pancreatic Neoplasms (1)  ·  Pathologic Complete Response (1)  ·  Postoperative Complications (1)  ·  Prostatic Neoplasms (1)  ·  Rectal Neoplasms (1)  ·  Sedentary Behavior (1)

Broader conditions

Neoplasms (18)  ·  Neoplasms by Site (17)  ·  Breast Diseases (9)  ·  Skin Diseases (9)  ·  Skin and Connective Tissue Diseases (9)  ·  Digestive System Diseases (5)  ·  Digestive System Neoplasms (5)  ·  Gastrointestinal Diseases (4)  ·  Gastrointestinal Neoplasms (4)  ·  Pathological Conditions, Signs and Symptoms (4)  ·  Lung Diseases (3)  ·  Pathologic Processes (3)  ·  Respiratory Tract Diseases (3)  ·  Respiratory Tract Neoplasms (3)  ·  Thoracic Neoplasms (3)

Interventions

Neoadjuvant Therapy (2)  ·  Standard of Care (2)  ·  130-nm albumin-bound paclitaxel (1)  ·  Ergocalciferols (1)  ·  Fluorouracil (1)  ·  Folfox protocol (1)  ·  Geriatric Assessment (1)  ·  Paclitaxel (1)  ·  Psychosocial Intervention (1)  ·  cemiplimab (1)  ·  dupilumab (1)  ·  pembrolizumab (1)

Sponsors

Fudan University (2)  ·  Fujian Medical University Union Hospital (2)  ·  Shanghai Pulmonary Hospital, Shanghai, China (2)  ·  Beijing Chao Yang Hospital (1)  ·  Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center (1)  ·  Centre hospitalier de l'Université de Montréal (CHUM) (1)  ·  Erasmus Medical Center (1)  ·  First Affiliated Hospital, Sun Yat-Sen University (1)  ·  Institut Investigacio Sanitaria Pere Virgili (1)  ·  Jena University Hospital (1)  ·  Jinsong Lu (1)  ·  Jiuda Zhao (1)  ·  M.D. Anderson Cancer Center (1)  ·  Mälardalen University (1)  ·  National Cancer Center, Korea (1)

Countries

China (13)  ·  Sweden (2)  ·  Canada (1)  ·  Netherlands (1)  ·  South Korea (1)  ·  Spain (1)  ·  United States (1)

Top investigators

Antoine Desilets, MD, MSc (1)  ·  Antonis Valachis, MD, PhD (1)  ·  China Fujian (1)  ·  Chuan Wang (1)  ·  Ernest JT Luiten, MD, PhD (1)  ·  Falk Rauchfuss, Prof (1)  ·  Jing Sun, PhD (1)  ·  Laia Estalella, PhD (1)  ·  Laura Schwenk, MD (1)  ·  Linetta B Koppert, MD, PhD (1)  ·  Marjolein L Smidt, MD, PhD (1)  ·  Rebecca A Snyder, MD (1)  ·  Seeyoun Lee, Doctor (1)  ·  Tao Zhen Yu, MD (1)

Results publications

PMID 16982773, PMID 17960012, PMID 18784101, PMID 21233014, PMID 21437225, PMID 23683750, PMID 24780112, PMID 25049329, PMID 25452445, PMID 28189914, PMID 28490940, PMID 28533474, PMID 29658848, PMID 29658856, PMID 30280658, PMID 30742122, PMID 31679945, PMID 33515668, PMID 33538338, PMID 38057662, PMID 39302345

NIH funding

2025 (1)