6 completed, 1 active not recruiting, 1 not yet recruiting, 1 unknown. 3 Phase 2, 2 Not applicable, 2 Phase 4, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 1, Not yet recruiting 1, Unknown 1 |
| Not applicable | 2 | Completed 2 |
| Phase 4 | 2 | Active not recruiting 1, Completed 1 |
| Phase 1 | 1 | Completed 1 |
Follow Naloxone: new trials by email Literature Review of Naloxone trials Research Report on Naloxone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Naloxone for Opioid Associated Out of Hospital Cardiac Arrest Naloxone 2 MG, Saline 2ml - Heart Arrest, Out-Of-Hospital, Opioid Overdose | Phase 2 | Not yet recruiting | University of California, San Francisco | 98 | 2027-03-01 | 2026-09-11 |
| Vending Machine Naloxone Distribution for Your Community (VENDY) VENDY - Harm Reduction, Naloxone | Phase 4 | Active not recruiting | University of Colorado, Denver | 4000 | 2024-06-01 | 2026-06-02 |
| Increasing Naloxone Access for Persons Who Use Opioids Opioid Overdose Education with Naloxone Distribution, Opioid Overdose Education - Naloxone | Phase 4 | Completed | University of Alabama at Birmingham | 111 | 2021-07-11 | 2023-10-30 |
| Nalox-Comm: Naloxone Communication Training for Pharmacists Nalox-comm Training Module, Prescribe to Prevent: Overdose Prevention and Naloxone Rescue Kits for Prescribers and Pharmacists - Naloxone | Not applicable | Completed | University of North Carolina, Chapel Hill | 48 | 2021-07-01 | 2024-06-26 |
| Effects of Intranasal Naloxone on Gambling Urges and Craving in Gambling Disorder Naloxone hydrochloride, Placebo - Pathological Gambling, Gambling Disorder | Phase 2 | Unknown | Finnish Institute for Health and Welfare | 126 | 2018-02-22 | 2019-07-16 |
| A Usability Assessment of Naloxone Administration by Untrained Community Members Nasal Spray Naloxone, Intramuscular Naloxone, Improvised Nasal Atomizer - Harm Reduction, Opioid-use Disorder | Not applicable | Completed | State University of New York - Upstate Medical University | 208 | 2017-08-23 | 2019-07-19 |
| Treatment of Gambling Disorder With Fast Acting Opiate Antagonist, Naloxone Nasal Spray Naloxone hydrochloride 20mg/ml - Gambling, Opioid | Phase 2 | Completed | Finnish Institute for Health and Welfare | 20 | 2017-02-14 | 2019-09-12 |
| Effect of High Dose Naloxone on Secondary Hyperalgesia Naloxone (2 mg/kg), Placebo - Hyperalgesia, Pain | Phase 1 | Completed | Copenhagen University Hospital, Rigshospitalet | 15 | 2013-06-01 | 2014-02-25 |
| Observational Study of Misuse of High Dose Buprenorphine (Subutex® or Generic) in Opiate-Addicted Patients in France (Study P05186AM1)(COMPLETED) buprenorphine - Buprenorphine, Naloxone | Completed | Indivior Inc. | 1307 | 2007-05-01 | 2023-03-20 |
Opiate Overdose (3) · Gambling (2) · Harm Reduction (2) · Opioid-Related Disorders (2) · Communication (1) · Hyperalgesia (1) · Out-of-Hospital Cardiac Arrest (1) · Pain (1) · Substance-Related Disorders (1)
Mental Disorders (7) · Behavior (5) · Chemically-Induced Disorders (5) · Narcotic-Related Disorders (5) · Substance-Related Disorders (4) · Drug Misuse (3) · Drug Overdose (3) · Opioid-Related Disorders (3) · Prescription Drug Misuse (3) · Disruptive, Impulse Control, and Conduct Disorders (2) · Risk-Taking (2) · Cardiovascular Diseases (1) · Heart Arrest (1) · Heart Diseases (1) · Nervous System Diseases (1)
Naloxone (5) · Buprenorphine (1) · Drugs, Generic (1) · Pharmacists (1) · Sodium Chloride (1)
Finnish Institute for Health and Welfare (2) · Copenhagen University Hospital, Rigshospitalet (1) · Indivior Inc. (1) · State University of New York - Upstate Medical University (1) · University of Alabama at Birmingham (1) · University of California, San Francisco (1) · University of Colorado, Denver (1) · University of North Carolina, Chapel Hill (1)
United States (5) · Finland (2) · Denmark (1)
Hannu Alho, Prof. (2) · Delesha Carpenter, PhD, MSPH (1) · Joergen B Dahl, M.D., DMSc (1) · Mads U. Werner, M.D., Ph.D., DMSc (1) · Michelle Sisson, MA (1) · Nicole Wagner, PhD (1) · Ralph Wang, MD, MAS (1)
PMID 36130734, PMID 37091508, PMID 37336007, PMID 39514898
2017 (1), R34DA046598 (1)