8 completed. 8 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 8 |
| Phase 2 | 2 | Completed 2 |
Follow NAFLD: new trials by email Literature Review of NAFLD trials Research Report on NAFLD
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Amino Acids on Hepatic Fat Content in Adolescents (AMINOS Study) Essential Amino Acid Supplement by Amino Co, Placebo - Hepatic Steatosis, NAFLD | Phase 3 | Completed | University of Colorado, Denver | 31 | 2024-06-18 | 2026-08-31 |
| Efficacy and Tolerability of Lubiprostone in Patients With Nonalcoholic Fatty Liver Disease Lubiprostone 24Mcg Oral twice daily - NAFLD | Phase 3 | Completed | Helwan University | 116 | 2020-11-01 | 2023-12-13 |
| Comparison of the Effects of Metformin and Pioglitazone on Liver Enzymes and Ultrasound Changes in Non-Diabetic Non-Alcoholic Fatty Liver Metformin and Pioglitazone - NAFLD | Phase 3 | Completed | King Edward Medical University | 96 | 2019-06-06 | 2022-08-30 |
| Treating PCOS With Semaglutide vs Active Lifestyle Intervention Semaglutide 3mg and 7mg [Rybelsus], Weight loss diet - PCOS, Adolescent Obesity | Phase 2 / Phase 3 | Completed | University of Colorado, Denver | 60 | 2019-05-03 | 2025-11-25 |
| Impact of a Specific Micronutrient-probiotic-supplement on Fatty Liver of Patients After Mini-Gastric Bypass Surgery Micronutrient-probiotic-combination, Micronutrient-placebo-combination - Obesity, Gastric Bypass | Phase 3 | Completed | Bonn Education Association for Dietetics r.A., Cologne, Germany | 60 | 2018-08-31 | 2020-09-25 |
| Hydroxytyrosol and Vitamin E in Pediatric NASH Hydroxytyrosol plus Vitamin E, Placebo - NAFLD | Phase 3 | Completed | Bambino Gesù Hospital and Research Institute | 80 | 2017-04-01 | 2018-07-17 |
| Resveratrol for the Treatment of Non Alcoholic Fatty Liver Disease and Insulin Resistance in Overweight Adolescents Resveratrol, Placebo - NAFLD, TYPE 2 DIABETES | Phase 2 / Phase 3 | Completed | University of Manitoba | 10 | 2015-08-01 | 2017-05-05 |
| DHA and Vitamin D in Children With Biopsy-proven NAFLD DHA plus Vitamin D, Placebo - NAFLD, Non Alcoholic Steatohepatitis (NASH) | Phase 3 | Completed | Bambino Gesù Hospital and Research Institute | 66 | 2014-01-01 | 2016-01-14 |
Non-alcoholic Fatty Liver Disease (8) · Obesity (2) · Pediatric Obesity (2) · Diabetes Mellitus, Type 2 (1) · Fatty Liver (1) · Insulin Resistance (1) · Metabolic Syndrome (1)
Digestive System Diseases (8) · Liver Diseases (8) · Fatty Liver (7) · Nutritional and Metabolic Diseases (5) · Body Weight (4) · Nutrition Disorders (4) · Overnutrition (4) · Overweight (4) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Glucose Metabolism Disorders (2) · Hyperinsulinism (2) · Metabolic Diseases (2) · Obesity (2) · Diabetes Mellitus (1)
3,4-dihydroxyphenylethanol (1) · Diet, Reducing (1) · Lubiprostone (1) · Metformin (1) · Pioglitazone (1) · Resveratrol (1) · Vitamin D (1) · Vitamin E (1) · alpha-Tocopherol (1) · semaglutide (1)
Bambino Gesù Hospital and Research Institute (2) · University of Colorado, Denver (2) · Bonn Education Association for Dietetics r.A., Cologne, Germany (1) · Helwan University (1) · King Edward Medical University (1) · University of Manitoba (1)
Italy (2) · United States (2) · Canada (1) · Egypt (1) · Germany (1) · Pakistan (1)
Brandy A Wicklow, MD, MSc (1) · Dr. Mohammad Ibrahim, MBBS, MD (1) · Karl Peter Rheinwalt, MD (1) · Melanie Cree, MD, PhD (1) · Melanie Cree-Green, MD, PhD (1) · Valerio Nobili, Professor (1)
PMID 33060043, PMID 34919684, PMID 39339810, PMID 39744921, PMID 42014131
R01DK120612 (1), R44DK135312 (1)