9 completed, 2 terminated, 1 active not recruiting, 1 unknown. 7 Not applicable, 4 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 3, Terminated 2, Active not recruiting 1, Withdrawn 1 |
| Phase 3 | 4 | Completed 4 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
Follow Musculoskeletal Complications: new trials by email Literature Review of Musculoskeletal Complications trials Research Report on Musculoskeletal Complications
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Genetics in Predicting Risk of Bisphosphonate-Related Osteonecrosis of the Jaw in Patients With Cancer Receiving Zoledronic Acid zoledronic acid, pharmacological study - Malignant Neoplasm, Musculoskeletal Complications | Not applicable | Withdrawn | University of Southern California | 2016-06-01 | 2017-04-11 | |
| Levocarnitine in Treating Patients With Vismodegib-Associated Muscle Spasms levocarnitine, placebo, questionnaire administration - Musculoskeletal Complications | Not applicable | Completed | Stanford University | 12 | 2014-03-01 | 2017-08-04 |
| Testosterone in Treating Postmenopausal Patients With Arthralgia Caused by Adjuvant Aromatase Inhibitor Treatment testosterone, placebo - Arthralgia, Breast Cancer | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 227 | 2013-09-10 | 2025-01-28 |
| A Study to Evaluate Genetic Predictors of Aromatase Inhibitor Musculoskeletal Symptoms (AIMSS) anastrozole - Estrogen Receptor-positive Breast Cancer, Musculoskeletal Complications | Not applicable | Active not recruiting | ECOG-ACRIN Cancer Research Group | 1046 | 2013-06-11 | 2026-08-27 |
| S1202: Duloxetine Hydrochloride for Muscle/Joint Pain in Early-Stage Breast Cancer Receiving Hormone Therapy duloxetine hydrochloride, placebo - Breast Cancer, Musculoskeletal Complications | Phase 3 | Completed | SWOG Cancer Research Network | 299 | 2013-05-15 | 2022-12-16 |
| Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation levofloxacin - Acute Leukemias of Ambiguous Lineage, Bacterial Infection | Phase 3 | Completed | Children's Oncology Group | 624 | 2011-09-01 | 2020-12-07 |
| First-Line Chemotherapy With or Without Neuromuscular Electrical Stimulation in Treating Patients With Non-Small Cell Lung Cancer carboplatin, vinorelbine tartrate, neuromuscular electrical stimulation - Chemotherapeutic Agent Toxicity, Fatigue | Phase 2 | Unknown | Wales Cancer Trials Unit | 52 | 2009-09-01 | 2011-08-08 |
| Prevention of Pegfilgrastim-Induced Bone Pain (PIBP) naproxen, placebo - Musculoskeletal Complications, Pain | Phase 3 | Completed | Gary Morrow | 510 | 2008-06-01 | 2015-11-09 |
| Image-Guided Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Shoulder, Arm, Hip, or Leg Chemotherapy, Radiation therapy, Surgery - Lymphedema, Musculoskeletal Complications | Phase 2 | Completed | Radiation Therapy Oncology Group | 98 | 2008-03-01 | 2019-06-12 |
| Testosterone Gel in Preventing Weakness Caused by Steroid Therapy in Men With Glioma testosterone gel applied to skin, whey powder protein - Brain and Central Nervous System Tumors, Musculoskeletal Complications | Not applicable | Terminated | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 1 | 2008-01-01 | 2018-08-27 |
| Vitamin D Deficiency, Muscle Pain, Joint Pain, and Joint Stiffness in Postmenopausal Women Receiving Letrozole For Stage I-III Breast Cancer letrozole, calcium carbonate, laboratory biomarker analysis - Arthralgia, Musculoskeletal Complications | Phase 2 | Completed | University of Washington | 100 | 2006-10-01 | 2017-07-11 |
| Comparison of Two Schedules of Zoledronic Acid in Treating Patients With Breast Cancer That Has Spread to the Bone zoledronic acid, quality-of-life assessment - Breast Cancer, Hypercalcemia of Malignancy | Not applicable | Terminated | University of Leeds | 1500 | 2006-03-01 | 2022-05-27 |
| Individualized Exercise Programs for Patients Receiving Chemotherapy for Newly Diagnosed Acute or Relapsed Myeloid Leukemia or Lymphoblastic Leukemia Resting vitals, Body Composition, Timed Get-up and Go test (TGUG). - Depression, Fatigue | Not applicable | Completed | UNC Lineberger Comprehensive Cancer Center | 10 | 2006-02-01 | 2012-03-06 |
| Using Whole-Person-Care Guide in Patients Receiving Care for Cancer or Complications From Cancer Treatment informational intervention, medical chart review, questionnaire administration - Chemotherapeutic Agent Toxicity, Infection | Not applicable | Completed | Northwestern University | 750 | 2001-07-01 | 2012-07-10 |
Breast Neoplasms (5) · Pain (4) · Arthralgia (2) · Fatigue (2) · Leukemia, Biphenotypic, Acute (2) · Neutropenia (2) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (2) · Radiation Injuries (2) · Astrocytoma (1) · Bacterial Infections (1) · Basal Cell Nevus Syndrome (1) · Breast Neoplasms, Male (1) · Carcinoma, Basal Cell (1) · Carcinoma, Non-Small-Cell Lung (1) · Central Nervous System Neoplasms (1)
Neoplasms (11) · Pathological Conditions, Signs and Symptoms (9) · Signs and Symptoms (8) · Neoplasms by Site (7) · Breast Diseases (5) · Neoplasms by Histologic Type (5) · Neurologic Manifestations (5) · Skin Diseases (5) · Skin and Connective Tissue Diseases (5) · Hemic and Lymphatic Diseases (4) · Hematologic Diseases (3) · Lymphatic Diseases (3) · Musculoskeletal Diseases (3) · Agranulocytosis (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2)
Therapeutics (2) · Zoledronic Acid (2) · Anastrozole (1) · Body Composition (1) · Calcium (1) · Calcium Carbonate (1) · Calcium Citrate (1) · Calcium Gluconate (1) · Carboplatin (1) · Carnitine (1) · Cholecalciferol (1) · Drug Therapy (1) · Duloxetine Hydrochloride (1) · Glucaric Acid (1) · Letrozole (1)
Alliance for Clinical Trials in Oncology (1) · Children's Oncology Group (1) · ECOG-ACRIN Cancer Research Group (1) · Gary Morrow (1) · Northwestern University (1) · Radiation Therapy Oncology Group (1) · SWOG Cancer Research Network (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1) · Stanford University (1) · UNC Lineberger Comprehensive Cancer Center (1) · University of Leeds (1) · University of Southern California (1) · University of Washington (1) · Wales Cancer Trials Unit (1)
United States (11) · Canada (2) · United Kingdom (2) · Puerto Rico (1)
Andrew Wilcock, MD (1) · Anne F. Schott, MD (1) · Anne Lynn Chang (1) · Burton L. Eisenberg, MD (1) · Charles Loprinzi, MD (1) · Claudio L. Battaglini, PhD (1) · David G. Kirsch, MD, PhD (1) · Dian Wang, MD, PhD (1) · Gary R. Morrow, PhD, MS (1) · Hannah Linden (1) · Jaishri O. Blakeley, MD (1) · Jeffrey J. Kirshner, MD (1) · Jeffrey K. Giguere, MD, FACP (1) · John M. Kane, MD (1) · Linda Emanuel, MD, PhD (1)
PMID 25667281, PMID 29136387, PMID 32372176, PMID 36995690
P30CA006973 (1), P30CA014089 (1), P30CA124435 (1), U10CA037403 (1), U10CA037420 (1), U10CA037429 (1), U10CA037447 (1), U10CA095861 (1), UG1CA189823 (1)