7 recruiting, 2 not yet recruiting, 1 completed. 4 Not applicable, 2 Early Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Recruiting 3, Not yet recruiting 1 |
| Early Phase 1 | 2 | Completed 1, Recruiting 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Microbiome Dysbiosis: new trials by email Literature Review of Microbiome Dysbiosis trials Research Report on Microbiome Dysbiosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trial Evaluating Nutritional Fiber in Digestive Symptoms of Endometriosis Fiber, Placebo - Endometriosis, Microbiome Dysbiosis | Not applicable | Recruiting | LOAM Science | 140 | 2026-10-01 | 2026-10-22 |
| The Bloom Infant Probiotic (BIP) Study Probiotic, Matching placebo - Infant, Newborn, Immunity | Phase 2 | Recruiting | South Australian Health and Medical Research Institute | 360 | 2026-05-25 | 2026-05-28 |
| LpD3.5 Intervention Study in Older Adults- LISA-I Trial LpD3.5, Placebo - Mild Cognitive Impairment (MCI), Cognition | Early Phase 1 | Recruiting | University of South Florida | 15 | 2026-03-03 | 2026-08-31 |
| Multi-Omics Integrative Analysis of Serum and Sputum to Uncover Key Determinants of Prognosis in Patients With ARDS Acute Respiratory Distress Syndrome (ARDS), Microbiome Dysbiosis | Not yet recruiting | Ruijin Hospital | 411 | 2026-03-01 | 2026-02-02 | |
| Accelerating Recovery After ICU Admission: Post-discharge Supplementation With Pasteurized Akkermansia Muciniphila. Pasteurized Akkermansia muciniphila, Placebo Control - Sepsis, Post Intensive Care Unit Syndrome | Not applicable | Not yet recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 50 | 2026-01-01 | 2025-12-19 |
| Dynamics of Dysbiosis in the Skin and Gut Microbiome of Burn Patients No Intervention: Observational Cohort - Burn Injuries, Skin Disease | Recruiting | Cho Yoon soo | 600 | 2025-09-15 | 2025-10-06 | |
| Pulmonary Microbiota Changes and Clinical Outcomes in Neurosurgical ICU Patients With Artificial Airways Ventilator-Associated Pneumonia (VAP), Intensive Care Unit (ICU) Patients | Recruiting | Jian-Xin Zhou | 220 | 2025-08-30 | 2026-05-22 | |
| Colon-delivered Riboflavin and Gut Microbiota Composition Colon-delivered riboflavin, Conventional riboflavin, Microcrystalline Cellulose - Microbiome Dysbiosis, Gut Health | Not applicable | Recruiting | dsm-firmenich Switzerland AG | 90 | 2025-07-18 | 2026-03-19 |
| Feasibility Study of Using Fecal Microbiota Transplants in Anorexia Nervosa Fecal Microbiome Transplant - Anorexia Nervosa, Microbiome Dysbiosis | Early Phase 1 | Completed | Hvidovre University Hospital | 17 | 2023-03-18 | 2025-06-27 |
| Synbiotics in Patients at RIsk fOr Preterm Birth Synbiotics, Placebo - Preterm Spontaneous Labor With Preterm Delivery, Preterm Birth | Not applicable | Recruiting | Ziekenhuis Oost-Limburg | 402 | 2023-03-16 | 2026-02-27 |
Anorexia Nervosa (1) · Burns (1) · Cognitive Dysfunction (1) · Communicable Diseases (1) · Critical Illness (1) · Dysbiosis (1) · Endometriosis (1) · Inflammation (1) · Pneumonia, Ventilator-Associated (1) · Premature Birth (1) · Respiratory Distress Syndrome (1) · Sepsis (1) · Skin Diseases (1)
Pathologic Processes (5) · Pathological Conditions, Signs and Symptoms (5) · Disease Attributes (3) · Infections (3) · Female Urogenital Diseases and Pregnancy Complications (2) · Lung Diseases (2) · Mental Disorders (2) · Respiratory Tract Diseases (2) · Urogenital Diseases (2) · Cognition Disorders (1) · Cross Infection (1) · Feeding and Eating Disorders (1) · Female Urogenital Diseases (1) · Genital Diseases (1) · Genital Diseases, Female (1)
Dietary Fiber (1) · Probiotics (1) · Synbiotics (1) · microcrystalline cellulose (1)
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Cho Yoon soo (1) · Hvidovre University Hospital (1) · Jian-Xin Zhou (1) · LOAM Science (1) · Ruijin Hospital (1) · South Australian Health and Medical Research Institute (1) · University of South Florida (1) · Ziekenhuis Oost-Limburg (1) · dsm-firmenich Switzerland AG (1)
United States (2) · Australia (1) · Belgium (1) · China (1) · Denmark (1) · Germany (1) · South Korea (1)
Bryce Jarman, PhD (1) · JW Wiersinga, Professor (1) · Jian-Xin Zhou, MD, PhD (1)
PMID 25948052, PMID 27763627, PMID 28709450, PMID 29282327, PMID 29682542, PMID 31814084, PMID 32129462, PMID 32302292, PMID 34500036, PMID 35535879, PMID 35573092, PMID 37213047, PMID 37224131, PMID 39289685, PMID 41535289