6 unknown, 3 completed, 2 not yet recruiting, 2 recruiting. 13 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 13 | Unknown 6, Completed 3, Not yet recruiting 2, Recruiting 2 |
Follow Metformin: new trials by email Literature Review of Metformin trials Research Report on Metformin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Osteogenic Potential of Topical Metformin Gel on Cystic Jaw Defects For the Experimental Arm: 1% Metformin Gel, For the Comparator / Control Arm: Placebo Gel - Jaw Cysts, Metformin | Not applicable | Not yet recruiting | Fayoum University | 32 | 2026-10-30 | 2026-10-14 |
| Interaction Between Inorganic Nitrate Supplementation and Metformin in Individuals With Prediabetes Dietary Supplement: Inorganic Nitrate (Beetroot juice), Dietary supplement: Placebo (Nitrate-depleted beetroot juice) - Males, Females | Not applicable | Recruiting | University of Virginia | 24 | 2026-01-01 | 2026-06-03 |
| Study of Acupuncture to Control Weight and Improve Pregnancy Rates in Overweight/Obese PCOS Patients Acupuncture+lifestyle intervention, Metformin+lifestyle intervention - Polycystic Ovary Syndrome, Metformin | Not applicable | Not yet recruiting | RenJi Hospital | 92 | 2024-12-20 | 2024-12-04 |
| PCOS Immune Function Predicts Metformin Efficacy Metformin - Polycystic Ovary Syndrome, Metformin | Not applicable | Unknown | Shanghai 10th People's Hospital | 100 | 2024-03-16 | 2024-03-22 |
| Effect of Metformin on Healthy Live Birth in Women With Prediabetes Metformin pretreatment before ovarian stimulation, Placebo pretreatment before ovarian stimulation, Metformin pretreatment before endometrial preparation for frozen embryo transfer - Metformin, Prediabetes | Not applicable | Recruiting | Shandong University | 988 | 2024-02-22 | 2024-05-29 |
| Effects of GLP-1RA on Body Weight, Metabolism and Fat Distribution in Overweight/Obese Patients With Type 2 Diabetes Mellitus Liraglutide, Semaglutide, Metformin - Metformin, Obesity, Abdominal | Not applicable | Unknown | RenJi Hospital | 300 | 2023-02-23 | 2023-05-16 |
| Ameliorating Metabolic Profiling After Kidney Transplantation (AMPKT) SGLT2 inhibitor, Metformin, Placebo - Kidney Transplantation, Metabolic Disorder | Not applicable | Completed | West China Hospital | 105 | 2023-01-01 | 2026-03-18 |
| Interactions of Medicine and Exercise With Meal Timing EXERCISE TRAINING WITH OR WITHOUT MEDICATION - Metabolic Syndrome, Protection Against, Exercise Training | Not applicable | Unknown | University of Castilla-La Mancha | 160 | 2022-06-07 | 2023-08-25 |
| The Effect of Exercise and Metformin on Carotid Intima-media Thickness in Patients With Prediabetes Exercise - Pre Diabetes, Exercise | Not applicable | Unknown | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | 90 | 2021-09-08 | 2022-06-22 |
| Effects of Exercise and Metformin on Methylglyoxal Levels in Prediabetic Individuals Exercise, Metformin - Methylglyoxal, PreDiabetes | Not applicable | Completed | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | 96 | 2021-04-08 | 2024-09-19 |
| Metformin for the Prevention of CRA Recurrence low-dose metformin, high-dose metformin, Placebo - Colorectal Adenoma, Metformin | Not applicable | Unknown | Jing-yuan Fang, MD, Ph. D | 414 | 2020-08-01 | 2021-05-13 |
| A Clinical Trial of Metformin to Decrease Glucocorticoids Side Effects in Patients With Autoimmune Uveitis Metformin, Placebo - Uveitis, Metformin | Not applicable | Unknown | Tianjin Medical University | 138 | 2018-11-01 | 2022-05-06 |
| Comparison of the Effectiveness Metformin for Deceasing Proliferative Marker in Endometrial Cancer Cells Metformin Hydrochloride 850 MG, Placebo Oral Tablet - Metformin, CA Endometrium | Not applicable | Completed | Department of Medical Services Ministry of Public Health of Thailand | 50 | 2018-07-01 | 2024-12-03 |
Prediabetic State (4) · Insulin Resistance (2) · Motor Activity (2) · Polycystic Ovary Syndrome (2) · Atherosclerosis (1) · Diabetes Mellitus, Type 2 (1) · Dyslipidemias (1) · Glucose Intolerance (1) · Glucose Metabolism Disorders (1) · Hypertension (1) · Intermittent Fasting (1) · Jaw Cysts (1) · Lipid Metabolism Disorders (1) · Metabolic Diseases (1) · Metabolic Syndrome (1)
Endocrine System Diseases (7) · Nutritional and Metabolic Diseases (7) · Metabolic Diseases (6) · Diabetes Mellitus (5) · Glucose Metabolism Disorders (5) · Behavior (4) · Cysts (3) · Neoplasms (3) · Adnexal Diseases (2) · Cardiovascular Diseases (2) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Genital Diseases (2) · Genital Diseases, Female (2) · Gonadal Disorders (2)
Metformin (8) · Exercise (3) · Dosage Forms (1) · Hydroxymethylglutaryl-CoA Reductase Inhibitors (1) · Liraglutide (1) · Sodium-Glucose Transporter 2 Inhibitors (1) · semaglutide (1)
RenJi Hospital (2) · Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey (2) · Department of Medical Services Ministry of Public Health of Thailand (1) · Fayoum University (1) · Jing-yuan Fang, MD, Ph. D (1) · Shandong University (1) · Shanghai 10th People's Hospital (1) · Tianjin Medical University (1) · University of Castilla-La Mancha (1) · University of Virginia (1) · West China Hospital (1)
China (7) · Turkey (Türkiye) (2) · Egypt (1) · Spain (1) · Thailand (1) · United States (1)
Jason Allen, PhD (1) · Jing-Yuan Fang, Professor (1) · Manna Zhang, doctor (1) · Tao Tao, MD (1) · Xiaorong Li, M.D. (1) · Zi-Jiang Chen, Professor (1)
PMID 12441176, PMID 16054041, PMID 17130214, PMID 21908880, PMID 21953589, PMID 24103089, PMID 26789102, PMID 27416781, PMID 27527232, PMID 38015017, PMID 39548448