2 completed, 1 available, 1 recruiting, 1 unknown. 2 Phase 1, 1 Early Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 1, Unknown 1 |
| Early Phase 1 | 1 | Recruiting 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Medulloepithelioma: new trials by email Literature Review of Medulloepithelioma trials Research Report on Medulloepithelioma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation Cytarabine IT, hydrocortisone, Cisplatin - CNS Embryonal Tumor, CNS, Medulloblastoma | Early Phase 1 | Recruiting | C17 Council | 15 | 2025-09-23 | 2026-07-14 |
| SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors Gemcitabine, ribociclib, sonidegib - Anaplastic Astrocytoma, Anaplastic Ependymoma | Phase 1 | Completed | St. Jude Children's Research Hospital | 68 | 2018-03-05 | 2024-05-31 |
| Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors Carboplatin, Mannitol, Melphalan - Central Nervous System Embryonal Neoplasm, Embryonal Tumor With Multilayered Rosettes, C19MC-Altered | Phase 1 / Phase 2 | Unknown | OHSU Knight Cancer Institute | 17 | 2009-07-09 | 2021-10-26 |
| Elucidating the Genetic Basis of the Pleuropulmonary Blastoma (PPB) Familial Cancer Syndrome Pleuropulmonary Blastoma, Cystic Nephroma | Completed | Ashley Hill | 1247 | 2005-03-01 | 2023-03-01 | |
| An Intermediate Expanded Use Trial of DFMO eflornithine HCl - Neuroblastoma, Medulloblastoma | Available | Giselle Sholler | 2026-02-20 |
Neuroectodermal Tumors, Primitive (5) · Medulloblastoma (4) · Pinealoma (3) · Neoplasms, Germ Cell and Embryonal (2) · Neuroblastoma (2) · Pyloric Stenosis, Hypertrophic (2) · Rhabdoid Tumor (2) · Astrocytoma (1) · Brain Neoplasms (1) · Central Nervous System Neoplasms (1) · Choroid Plexus Carcinoma (1) · Ependymoma (1) · Glioblastoma (1) · Glioma (1) · Goiter (1)
Neoplasms by Histologic Type (5) · Neoplasms, Glandular and Epithelial (5) · Neoplasms, Nerve Tissue (5) · Neuroectodermal Tumors (5) · Neoplasms (4) · Neoplasms, Neuroepithelial (4) · Brain Diseases (3) · Central Nervous System Diseases (3) · Glioma (3) · Neoplasms by Site (3) · Neoplasms, Complex and Mixed (3) · Neoplasms, Germ Cell and Embryonal (3) · Nervous System Diseases (3) · Nervous System Neoplasms (3) · Brain Neoplasms (2)
Carboplatin (2) · Filgrastim (2) · Granulocyte Colony-Stimulating Factor (2) · Celecoxib (1) · Cisplatin (1) · Cyclophosphamide (1) · Eflornithine (1) · Etoposide (1) · Gemcitabine (1) · Hydrocortisone (1) · Isotretinoin (1) · Mannitol (1) · Melphalan (1) · Mesna (1) · Tamoxifen (1)
Ashley Hill (1) · C17 Council (1) · Giselle Sholler (1) · OHSU Knight Cancer Institute (1) · St. Jude Children's Research Hospital (1)
United States (4) · Canada (1)
Annie Huang (1) · D. Ashley Hill, MD (1) · Edward A Neuwelt (1) · Giles W. Robinson, MD (1) · Giselle Sholler, MD (1) · Kris Ann Schultz, MD (1) · Lucie Lafay-Cousin (1) · Sylvia Cheng (1)
PMID 19556464, PMID 24481001, PMID 24761742, PMID 24821309, PMID 24909177, PMID 25118636, PMID 25209242, PMID 25356068, PMID 26555935, PMID 26925222, PMID 28323992, PMID 28748527, PMID 29037807, PMID 29343557
R01NS044687 (1)