4 recruiting, 3 completed, 2 terminated, 1 active not recruiting. 9 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 9 | Completed 3, Recruiting 3, Active not recruiting 1, Terminated 1, Withdrawn 1 |
Follow Choroid Plexus Carcinoma: new trials by email Literature Review of Choroid Plexus Carcinoma trials Research Report on Choroid Plexus Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors NEO100 - Pediatric Tumor of CNS, Pediatric Tumor of Brain | Phase 1 | Recruiting | Neonc Technologies, Inc. | 12 | 2026-09-08 | 2026-09-15 |
| Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors Anaplastic Astrocytoma, Diffuse Brainstem Glioma | Terminated | Pediatric Brain Tumor Consortium | 57 | 2023-07-12 | 2026-04-23 | |
| Intra-Arterial Chemotherapy for Newly Diagnosed, Residual, or Recurrent Atypical Choroid Plexus Papilloma and Choroid Plexus Carcinoma Prior to Second-Look Surgery Melphalan, Carboplatin, Topotecan - Atypical Choroid Plexus Papilloma, Choroid Plexus Carcinoma | Phase 1 | Terminated | Weill Medical College of Cornell University | 1 | 2023-05-04 | 2026-06-08 |
| Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer Etoposide, Fludarabine Phosphate, Hematopoietic Cell Transplantation - Anaplastic Ependymoma, Atypical Teratoid/Rhabdoid Tumor | Phase 1 | Withdrawn | M.D. Anderson Cancer Center | 2021-01-14 | 2024-10-26 | |
| Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors SCRI-CARB7H3(s); B7H3-specific chimeric antigen receptor (CAR) T cel - Central Nervous System Tumor, Diffuse Intrinsic Pontine Glioma | Phase 1 | Recruiting | Seattle Children's Hospital | 90 | 2019-12-11 | 2026-04-13 |
| HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors G207 - Neoplasms, Brain, Glioblastoma Multiforme | Phase 1 | Recruiting | M.D. Anderson Cancer Center | 24 | 2019-09-12 | 2026-09-04 |
| EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors EGFR806-specific chimeric antigen receptor (CAR) T cell - Central Nervous System Tumor, Pediatric, Glioma | Phase 1 | Completed | Seattle Children's Hospital | 11 | 2019-03-19 | 2025-12-17 |
| HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors HER2-specific chimeric antigen receptor (CAR) T cell - Central Nervous System Tumor, Pediatric, Glioma | Phase 1 | Active not recruiting | Seattle Children's Hospital | 10 | 2018-07-26 | 2025-12-17 |
| SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors Gemcitabine, ribociclib, sonidegib - Anaplastic Astrocytoma, Anaplastic Ependymoma | Phase 1 | Completed | St. Jude Children's Research Hospital | 68 | 2018-03-05 | 2024-05-31 |
| Familial Investigations of Childhood Cancer Predisposition Acute Leukemia, Adenomatous Polyposis | Recruiting | St. Jude Children's Research Hospital | 1500 | 2017-04-06 | 2026-06-17 | |
| HSV G207 Alone or With a Single Radiation Dose in Children With Progressive or Recurrent Supratentorial Brain Tumors G207 - Supratentorial Neoplasms, Malignant, Malignant Glioma | Phase 1 | Completed | Gregory K. Friedman, MD | 13 | 2016-05-01 | 2024-01-19 |
Brain Neoplasms (8) · Ependymoma (8) · Glioma (8) · Rhabdoid Tumor (8) · Central Nervous System Neoplasms (7) · Medulloblastoma (7) · Neuroectodermal Tumors, Primitive (7) · Neoplasms, Germ Cell and Embryonal (6) · Pinealoma (6) · Astrocytoma (4) · Glioblastoma (4) · Oligodendroglioma (4) · Neoplasms (3) · Gliosarcoma (2)
Neoplasms by Histologic Type (9) · Neoplasms by Site (9) · Neoplasms, Glandular and Epithelial (9) · Neoplasms, Nerve Tissue (9) · Nervous System Diseases (9) · Neuroectodermal Tumors (9) · Brain Diseases (8) · Central Nervous System Diseases (8) · Neoplasms, Complex and Mixed (8) · Neoplasms, Neuroepithelial (8) · Nervous System Neoplasms (8) · Neoplasms (7) · Neoplasms, Germ Cell and Embryonal (4) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3)
Automobiles (3) · Melphalan (2) · Antilymphocyte Serum (1) · Carboplatin (1) · Etoposide (1) · Filgrastim (1) · Gemcitabine (1) · Granulocyte Colony-Stimulating Factor (1) · Hematopoietic Stem Cell Transplantation (1) · Mycophenolic Acid (1) · Stem Cell Transplantation (1) · Tacrolimus (1) · Thiotepa (1) · Topotecan (1) · fludarabine phosphate (1)
Seattle Children's Hospital (3) · M.D. Anderson Cancer Center (2) · St. Jude Children's Research Hospital (2) · Gregory K. Friedman, MD (1) · Neonc Technologies, Inc. (1) · Pediatric Brain Tumor Consortium (1) · Weill Medical College of Cornell University (1)
United States (10) · Canada (1)
Rebecca Ronsley, MD (2) · Alexandra Miller, MD, PhD (1) · Giles W. Robinson, MD (1) · Gregory Friedman, MD (1) · Gregory K Friedman, M.D. (1) · Josh Neman, PhD (1) · Juliane Gust, MD, PhD (1) · Kim E. Nichols, MD (1) · Kris M Mahadeo, MD (1) · Mark Souweidane, M.D. (1) · Thomas Chen, MD, PhD (1)
PMID 33838625, PMID 34253928, PMID 35468680, PMID 37640679, PMID 39775044, PMID 41798119
UM1CA081457 (1)