7 completed. 7 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 7 |
| Phase 1 | 3 | Completed 3 |
Follow Malignant Solid Neoplasm: new trials by email Literature Review of Malignant Solid Neoplasm trials Research Report on Malignant Solid Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Topical Cannabidiol for the Treatment of Chemotherapy-Induced Peripheral Neuropathy Cannabidiol, Placebo Administration, Quality-of-Life Assessment - Chemotherapy-Induced Peripheral Neuropathy, Malignant Solid Neoplasm | Phase 2 | Completed | Mayo Clinic | 40 | 2022-06-09 | 2026-01-16 |
| Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1) nab-sirolimus - Tumor, Tumor, Solid | Phase 2 | Completed | Aadi Bioscience, Inc. | 128 | 2022-03-10 | 2026-10-28 |
| PHASE II SINGLE-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE, STUDY TO DETERMINE THE IMPACT OF SERIAL PROCALCITONIN Imipenem/Cilastatin/Relebactam, Cefepime, Meropenem - Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm | Phase 2 | Completed | M.D. Anderson Cancer Center | 100 | 2021-09-14 | 2026-04-06 |
| Leflunomide for the Treatment of Severe COVID-19 in Patients With a Concurrent Malignancy Best Practice, Leflunomide, Placebo Administration - Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm | Phase 1 / Phase 2 | Completed | City of Hope Medical Center | 2 | 2021-01-07 | 2024-07-03 |
| Alisertib and Pembrolizumab for the Treatment of Patients With Rb-deficient Head and Neck Squamous Cell Cancer Alisertib, Pembrolizumab - Head and Neck Squamous Cell Carcinoma, Malignant Solid Neoplasm | Phase 1 / Phase 2 | Completed | M.D. Anderson Cancer Center | 24 | 2020-09-15 | 2025-05-20 |
| Carvedilol in Preventing Heart Failure in Childhood Cancer Survivors Carvedilol, Laboratory Biomarker Analysis, Pharmacogenomic Study - Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm | Phase 2 | Completed | Children's Oncology Group | 196 | 2016-04-04 | 2025-04-23 |
| Pembrolizumab and Stereotactic Body Radiation Therapy or Non-Stereotactic Wide-Field Radiation Therapy in Treating Patients With Non-small Cell Lung Cancer 3-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, Laboratory Biomarker Analysis - Malignant Solid Neoplasm, Metastatic Lung Non-Small Cell Carcinoma | Phase 1 / Phase 2 | Completed | M.D. Anderson Cancer Center | 124 | 2015-09-17 | 2026-05-15 |
Hematologic Neoplasms (3) · Carcinoma, Non-Small-Cell Lung (1) · Head and Neck Neoplasms (1) · Hereditary Sensory and Autonomic Neuropathies (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Squamous Cell Carcinoma of Head and Neck (1) · Tuberous Sclerosis 1 (1) · Tuberous Sclerosis 2 (1)
Neoplasms (5) · Neoplasms by Site (5) · Hematologic Diseases (3) · Hemic and Lymphatic Diseases (3) · Bronchial Neoplasms (1) · Carcinoma (1) · Carcinoma, Bronchogenic (1) · Carcinoma, Squamous Cell (1) · Congenital Abnormalities (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Genetic Diseases, Inborn (1) · Heredodegenerative Disorders, Nervous System (1) · Lung Diseases (1) · Lung Neoplasms (1) · Neoplasms by Histologic Type (1)
pembrolizumab (2) · Cannabidiol (1) · Carvedilol (1) · Cefepime (1) · Daptomycin (1) · Leflunomide (1) · Linezolid (1) · MLN 8237 (1) · Meropenem (1) · Pharmacogenomic Testing (1) · Piperacillin, Tazobactam Drug Combination (1) · Practice Guidelines as Topic (1) · Proton Therapy (1) · Protons (1) · Radiation (1)
M.D. Anderson Cancer Center (3) · Aadi Bioscience, Inc. (1) · Children's Oncology Group (1) · City of Hope Medical Center (1) · Mayo Clinic (1)
United States (7) · Australia (1) · Canada (1) · New Zealand (1) · Puerto Rico (1) · South Korea (1)
Faye M Johnson, MD (1) · Issam I Raad (1) · James Welsh (1) · Sanjeet S Dadwal (1) · Saro H Armenian (1) · Stacy D. D'Andre, M.D. (1)
PMID 27716152, PMID 31996395, PMID 33051340, PMID 33096027, PMID 34749885, PMID 39016024, PMID 39456544
P30CA033572 (1), R01CA196854 (1), UG1CA189955 (1)