6 completed, 2 recruiting, 1 withdrawn. 3 Phase 1, 1 Early Phase 1, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 2, Withdrawn 1 |
| Early Phase 1 | 1 | Completed 1 |
| Not applicable | 1 | Completed 1 |
Follow Malignant Central Nervous System Neoplasm: new trials by email Literature Review of Malignant Central Nervous System Neoplasm trials Research Report on Malignant Central Nervous System Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pharmacodynamic Analyses of Metabolic Agents Following Brain Radiation Anhydrous Enol-oxaloacetate, Best Practice, Biospecimen Collection - Malignant Central Nervous System Neoplasm | Phase 1 | Withdrawn | Mayo Clinic | 2025-10-20 | 2025-10-22 | |
| Patient and Caregiver Priorities in Neuro-oncology Care Non-Interventional Study - Malignant Central Nervous System Neoplasm, Metastatic Malignant Neoplasm in the Central Nervous System | Completed | Mayo Clinic | 33 | 2024-04-24 | 2026-04-01 | |
| Study of Human Brain-Gut Axis and Gut Microbiome in Patients With Brain Lesions - Repository for Neuroscience Research Non-Interventional Study - Malignant Central Nervous System Neoplasm | Recruiting | Mayo Clinic | 100 | 2024-02-28 | 2026-02-05 | |
| Pro-Active Genetic Testing in Patients With Solid Tumors, Inherit Study Biospecimen Collection, Genetic Counseling, Genetic Testing - Breast Carcinoma, Digestive System Neoplasm | Phase 1 | Completed | Mayo Clinic | 230 | 2020-06-29 | 2023-07-24 |
| Memantine for the Reduction of Cognitive Impairment After Radiation Therapy in Pediatric Patients With Central Nervous System Tumors Cogstate Assessment Battery, Memantine, Memantine Hydrochloride - Malignant Central Nervous System Neoplasm, Primary Central Nervous System Neoplasm | Early Phase 1 | Completed | Mayo Clinic | 18 | 2020-02-17 | 2024-11-21 |
| Vertebral Body Sparing Craniospinal Irradiation for Pediatric Patients With Cancer of the Central Nervous System Intensity-Modulated Proton Therapy, Magnetic Resonance Imaging - Malignant Central Nervous System Neoplasm | Not applicable | Completed | Emory University | 10 | 2019-12-16 | 2024-03-21 |
| Brain Imaging Changes Following Proton Therapy for Pediatric Primary Central Nervous System and Base of Skull Tumors Medical Chart Review - Malignant Central Nervous System Neoplasm, Malignant Skull Base Neoplasm | Completed | Mayo Clinic | 36 | 2019-01-21 | 2024-05-17 | |
| Hyperpolarized Carbon C 13 Pyruvate Magnetic Resonance Spectroscopic Imaging in Detecting Lactate and Bicarbonate in Participants With Central Nervous System Tumors Gadolinium, Hyperpolarized Carbon C 13 Pyruvate, Magnetic Resonance Imaging - Malignant Central Nervous System Neoplasm, Metastatic Malignant Neoplasm in the Central Nervous System | Phase 1 | Completed | Daniel M. Spielman | 9 | 2018-11-06 | 2023-12-21 |
| Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated With Proton Therapy Quality-of-Life Assessment, Questionnaire Administration - Breast Carcinoma, Esophageal Carcinoma | Recruiting | M.D. Anderson Cancer Center | 5000 | 2005-05-27 | 2026-06-12 |
Central Nervous System Neoplasms (9) · Breast Neoplasms (2) · Brain Neoplasms (1) · Digestive System Neoplasms (1) · Esophageal Neoplasms (1) · Gastrointestinal Neoplasms (1) · Head and Neck Neoplasms (1) · Hematologic Neoplasms (1) · Lung Neoplasms (1) · Neoplasms, Unknown Primary (1) · Urogenital Neoplasms (1)
Neoplasms (9) · Neoplasms by Site (9) · Nervous System Diseases (9) · Nervous System Neoplasms (9) · Breast Diseases (2) · Digestive System Diseases (2) · Skin Diseases (2) · Skin and Connective Tissue Diseases (2) · Brain Diseases (1) · Central Nervous System Diseases (1) · Digestive System Neoplasms (1) · Esophageal Diseases (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Gastrointestinal Diseases (1)
Magnetic Resonance Spectroscopy (3) · Gadolinium (1) · Genetic Counseling (1) · Genetic Testing (1) · Memantine (1) · Oxaloacetic Acid (1) · Practice Guidelines as Topic (1) · Specimen Handling (1) · Standard of Care (1)
Mayo Clinic (6) · Daniel M. Spielman (1) · Emory University (1) · M.D. Anderson Cancer Center (1)
United States (9)
Alfredo Quinones-Hinojosa, M.D. (1) · Bree R Eaton (1) · Lawrence Recht (1) · Nadia N. Laack, M.D. (1) · Niloy J Samadder (1) · Steven J Frank (1) · Tamara Z. Vern-Gross, D.O. (1) · Terence C. Burns, MD, PhD (1) · Ugur T. Sener, MD (1)
P30CA138292 (1), R01CA245097 (1)