18 completed, 7 unknown, 5 recruiting, 2 not yet recruiting. 8 Not applicable, 8 Phase 1, 4 Phase 2, 2 Phase 4.
Follow Lupus Erythematosus: new trials by email Literature Review of Lupus Erythematosus trials Research Report on Lupus Erythematosus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy, in Patients With Refractory Systemic Lupus Erythematosus (GALLOP) CB-010 - Systemic Lupus Erythematosus, Lupus | Phase 1 | Withdrawn | Caribou Biosciences, Inc. | 2027-12-01 | 2025-09-19 | |
| Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stress TEAM-LEADS - Lupus, Dermatomyositis, Juvenile | Not applicable | Not yet recruiting | Duke University | 25 | 2027-02-01 | 2026-05-27 |
| Identification of Modifiable Sleep-related Factors in Patients With Systemic Lupus Erythematosus. Adults with systemic lupus erythematosus - Lupus Erythematosus | Not yet recruiting | Investigación en Hemofilia y Fisioterapia | 250 | 2026-05-05 | 2026-05-04 | |
| The Role of Cytokines and Regulatory T Lymphocytes in Migraine Pathophysiology. Blood test - Migraine Disorders, Pain | Not applicable | Recruiting | University Hospital, Clermont-Ferrand | 396 | 2025-06-02 | 2025-11-20 |
| Study Evaluating SC291 in Subjects With Severe r/r B-cell Mediated Autoimmune Diseases (GLEAM) SC291 - Lupus Erythematosus, Systemic Lupus Erythematosus | Phase 1 | Active not recruiting | Sana Biotechnology | 7 | 2024-04-29 | 2025-11-25 |
| Description of Compliance With Hydroxychloroquine Treatment in Patients With Systemic Lupus Erythematosus The Morisky Medication Adherence Scale - Lupus Erythematosus | Completed | University Hospital, Toulouse | 102 | 2023-11-27 | 2025-12-31 | |
| A Study of Imvotamab in Severe Systemic Lupus Erythematosus Imvotamab - Systemic Lupus Erythematosus, Lupus Erythematosus | Phase 1 | Terminated | IGM Biosciences, Inc. | 17 | 2023-08-15 | 2025-02-10 |
| Exploring Accessible Beauty for Individuals With Upper Extremity Deficits Use of Rare Beauty makeup products - Stroke, Ischemic, Stroke Hemorrhagic | Completed | Casa Colina Hospital and Centers for Healthcare | 57 | 2023-07-21 | 2023-12-06 | |
| The Living With a Long-Term Condition Study Living with LTC Questionnaire - Asthma, Atrial Fibrillation | Unknown | King's College London | 600 | 2023-06-28 | 2023-10-12 | |
| Treatment of Lupus Nephritis With Allogeneic Mesenchymal Stem Cells Mesenchymal stem cells (MSC), Placebo - Lupus Nephritis, Lupus Erythematosus | Phase 2 | Recruiting | Red de Terapia Celular | 20 | 2022-12-27 | 2026-08-18 |
| Transition to Adulthood Through Coaching and Empowerment in Rheumatology Transition coaching - Juvenile Idiopathic Arthritis, Juvenile Rheumatoid Arthritis | Not applicable | Completed | McMaster University | 26 | 2022-10-17 | 2026-02-11 |
| The Effects of Mesenchymal Stem Cell Secretome in Lupus Patients Secretome, Placebo - Lupus Erythematosus | Phase 1 / Phase 2 | Completed | Universitas Sebelas Maret | 15 | 2022-08-01 | 2023-06-27 |
| Clinico-biological Collection to Investigate the Physiopathology of Systemic Autoimmune Diseases Blood sampling - Lupus Erythematosus, Scleroderma | Recruiting | University Hospital, Toulouse | 3000 | 2022-04-04 | 2026-03-17 | |
| Methyl-donor Nutrient Supplementation and Methylation Profile in Lupus Patients With Obesity Vitamin B12 + folic acid supplementation, Placebo supplementation - Overweight and Obesity, Lupus Erythematosus | Not applicable | Enrolling by invitation | University of Sao Paulo | 51 | 2022-01-01 | 2024-05-02 |
| The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic Exposure of interest - Alopecia Areata, Alopecia Totalis | Completed | Faculty Hospital Kralovske Vinohrady | 123 | 2021-10-15 | 2024-12-03 | |
| Trial of Belimumab in Early Lupus Belimumab, Belimumab/Placebo, Placebo - Lupus Erythematosus, Systemic, Lupus Erythematosus | Phase 4 | Recruiting | Northwell Health | 30 | 2020-09-15 | 2026-06-12 |
| Long-term Immunogenicity of a Live Herpes Zoster Vaccine in Systemic Lupus Erythematosus (SLE) Patients Immunogenicity - Lupus Erythematosus | Completed | Tuen Mun Hospital | 68 | 2020-06-01 | 2024-02-16 | |
| Mobile Study to Measure and Predict Lupus Disease Activity Using Digital Signals Lupus Erythematosus, Systemic, Lupus Erythematosus | Unknown | Progentec Diagnostics, Inc. | 300 | 2020-04-28 | 2020-06-29 | |
| A Pilot Study to Explore the Role of Gut Flora in Lupus No Intervention - Lupus Erythematosus, Lupus Erythematosus, Systemic | Withdrawn | ProgenaBiome | 2020-03-02 | 2025-06-05 | ||
| Study of EQ001 (Itolizumab) in Systemic Lupus Erythematosus With or Without Active Proliferative Nephritis Itolizumab [Bmab 600] - Lupus Erythematosus, Lupus Nephritis | Phase 1 | Completed | Biocon Limited | 52 | 2019-10-01 | 2026-06-04 |
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Lupus Erythematosus, Systemic (15) · Autoimmune Diseases (8) · Arthritis, Rheumatoid (7) · Multiple Sclerosis (6) · Amyotrophic Lateral Sclerosis (4) · Crohn Disease (4) · Lupus Nephritis (4) · Psoriasis (4) · Anxiety Disorders (3) · Depression (3) · Dermatomyositis (3) · Diabetes Mellitus (3) · Eczema (3) · Inflammatory Bowel Diseases (3) · Migraine Disorders (3)
Immune System Diseases (26) · Skin and Connective Tissue Diseases (26) · Connective Tissue Diseases (25) · Autoimmune Diseases (16) · Musculoskeletal Diseases (11) · Nervous System Diseases (10) · Skin Diseases (10) · Joint Diseases (8) · Pathological Conditions, Signs and Symptoms (8) · Rheumatic Diseases (8) · Signs and Symptoms (8) · Arthritis (7) · Muscular Diseases (7) · Neuromuscular Diseases (7) · Nutritional and Metabolic Diseases (7)
Blood Specimen Collection (2) · Cyclophosphamide (2) · Hematologic Tests (2) · fludarabine (2) · Eating (1) · Genes, mos (1) · Immunogenicity, Vaccine (1) · Mycophenolic Acid (1) · Prednisone (1) · Saline Solution (1) · Secretome (1) · Tacrolimus (1) · Vitamin B 12 (1) · Whole-Body Irradiation (1) · belimumab (1)
ProgenaBiome (2) · Progentec Diagnostics, Inc. (2) · University Hospital, Toulouse (2) · AbbVie (prior sponsor, Abbott) (1) · Ampel BioSolutions, LLC (1) · Assistance Publique - Hôpitaux de Paris (1) · Assistance Publique Hopitaux De Marseille (1) · Biocon Limited (1) · CHU de Reims (1) · Caribou Biosciences, Inc. (1) · Casa Colina Hospital and Centers for Healthcare (1) · Centre Hospitalier Universitaire Dijon (1) · Duke University (1) · DxTerity Diagnostics (1) · Faculty Hospital Kralovske Vinohrady (1)
United States (19) · France (10) · Poland (2) · Spain (2) · Brazil (1) · Canada (1) · China (1) · Czechia (1) · Germany (1) · India (1) · Indonesia (1) · Mexico (1) · Puerto Rico (1) · South Korea (1) · United Kingdom (1)
Eldon Jupe, Ph.D. (2) · Sabine Hazan, MD (2) · Annie Jones, PhD (1) · Chi Chiu Mok (1) · Cynthia Aranow, MD (1) · Emily Rosario, PhD (1) · Emma Jenkinson, MSc (1) · Jean-Yves Cesbron, MD (1) · Julia Barbado, MD, PhD (1) · Kaveh Ardalan, MD, MS (1) · Kenneth Kalunian, MD (1)
PMID 11381086, PMID 12480667, PMID 20652065, PMID 22315398, PMID 22615568, PMID 22733998, PMID 23144449, PMID 23452295, PMID 23584529, PMID 23754628, PMID 27459457, PMID 28691866, PMID 29333561, PMID 31541431, PMID 31620787, PMID 33850015, PMID 34181079, PMID 34912736, PMID 35185888, PMID 35483736, PMID 36079877, PMID 36655762, PMID 36839324, PMID 39375179, PMID 39706212, PMID 41484640, PMID 41666998
K23AR084475 (1), UL1TR001082 (1)