4 active not recruiting. 4 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Active not recruiting 4 |
| Phase 2 | 2 | Active not recruiting 2 |
Follow Liver Failure: new trials by email Literature Review of Liver Failure trials Research Report on Liver Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase I Trial of QH-1A Hybrid Bio-Artificial Liver With Ex Vivo Blood-Purifying MSCs in Acute-on-Chronic Liver Failure Combining the QH-1A bioartificial liver device with mesenchymal stem cells for blood purification（4 hours）, Combining the QH-1A bioartificial liver device with mesenchymal stem cells for blood purification（6 hours）, Combining the QH-1A bioartificial liver device with mesenchymal stem cells for blood purification（8 hours） - Acute-On-Chronic Liver Failure | Phase 1 | Active not recruiting | Third Affiliated Hospital, Sun Yat-Sen University | 15 | 2025-05-07 | 2025-05-30 |
| RTX001 Autologous Engineered Macrophages for Liver Cirrhosis RTX001 - End-stage Liver Disease (ESLD), Cirrhosis, Liver | Phase 1 / Phase 2 | Active not recruiting | Resolution Therapeutics Limited | 30 | 2024-10-15 | 2026-10-05 |
| Safety and Clinical Activity of QEL-001 in A2-mismatch Liver Transplant Patients QEL-001 - Rejection; Transplant, Liver, Liver Failure | Phase 1 / Phase 2 | Active not recruiting | Quell Therapeutics Limited | 33 | 2022-01-21 | 2026-07-02 |
| Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction Carboplatin, Laboratory Biomarker Analysis, Paclitaxel - Breast Carcinoma, Carcinoma of Unknown Primary | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 94 | 2011-06-20 | 2026-09-04 |
Liver Diseases (2) · Acute-On-Chronic Liver Failure (1) · Breast Neoplasms (1) · Carcinoma, Transitional Cell (1) · End Stage Liver Disease (1) · Endometrial Neoplasms (1) · Esophageal Neoplasms (1) · Fibrosis (1) · Head and Neck Neoplasms (1) · Hepatic Encephalopathy (1) · Jaundice (1) · Liver Cirrhosis (1) · Lung Neoplasms (1) · Melanoma (1)
Digestive System Diseases (4) · Hepatic Insufficiency (4) · Liver Diseases (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Adnexal Diseases (1) · Behavior (1) · Brain Diseases (1) · Brain Diseases, Metabolic (1) · Breast Diseases (1) · Carcinoma (1) · Central Nervous System Diseases (1) · Digestive System Neoplasms (1) · Endocrine Gland Neoplasms (1)
Carboplatin (1) · Paclitaxel (1) · Taxes (1) · veliparib (1)
National Cancer Institute (NCI) (1) · Quell Therapeutics Limited (1) · Resolution Therapeutics Limited (1) · Third Affiliated Hospital, Sun Yat-Sen University (1)
Spain (2) · United Kingdom (2) · Belgium (1) · China (1) · United States (1)
Hussein A Tawbi (1)
N01CM00100 (1), P30CA047904 (1), U01CA062490 (1), U01CA062502 (1), U01CA062505 (1), U01CA069856 (1), U01CA070095 (1), U01CA099168 (1), UM1CA186690 (1), UM1CA186691 (1), UM1CA186709 (1), UM1CA186716 (1), UM1CA186717 (1)