73 completed, 21 unknown, 13 terminated, 6 withdrawn. 31 Not applicable, 19 Phase 1, 15 Phase 4, 14 Phase 2, 8 Phase 3.
Follow Liver Disease: new trials by email Literature Review of Liver Disease trials Research Report on Liver Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Digital Behavioral Therapy to Reduce Diabetes and Liver Disease Risk Behavioral Treatment - Type 2 Diabetes, Liver Disease | Not applicable | Not yet recruiting | SIPPA Solutions INC | 180 | 2026-08-20 | 2026-09-14 |
| Management Concepts of Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) Among Chinese Physicians No treatment is given - Liver Disease | Recruiting | Novo Nordisk A/S | 470 | 2026-06-03 | 2026-07-02 | |
| Cobas® Lumira Collection of Venous and Capillary Blood Samples for the Research, Optimization and Calibration of New Diagnostic Devices Blood samples are obtained and pseudonymized, prior to use for the development, optimization and calibration of diagnostic tests - Blood Clots, Infection and Inflammatory Reaction | Not yet recruiting | LumiraDx UK Limited | 30000 | 2026-04-01 | 2026-01-30 | |
| Alternate Dosing Study of MK-6024 in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) (MK-6024-016) Efinopegdutide - Metabolic Dysfunction-Associated Steatotic Liver Disease, Non-alcoholic Fatty Liver Disease | Phase 2 | Completed | Merck Sharp & Dohme LLC | 124 | 2024-07-29 | 2026-06-01 |
| Online Prehabilitation for Patients Awaiting Liver Transplantation Prehabilitation Programming - Cirrhosis, Liver, Liver Transplant Surgery | Not applicable | Active not recruiting | University of Alberta | 179 | 2023-07-12 | 2026-11-04 |
| Effectiveness and Safety of the COVID-19 Vaccination for Patients With Liver Disease (CHESS2101) COVID-19, Liver Disease | Completed | Hepatopancreatobiliary Surgery Institute of Gansu Province | 1000 | 2021-05-11 | 2023-04-25 | |
| The Purpose of This Study is to Investigate Safety and Tolerability of Tropifexor. triopifexor, Placebo - Liver Disease | Phase 1 | Completed | Novartis Pharmaceuticals | 89 | 2020-05-29 | 2022-02-09 |
| Safety and Efficacy of Fecal Microbiota Transplantation Fecal Microbiota Transplantation - Crohn Disease, Ulcerative Colitis | Not applicable | Recruiting | Chinese University of Hong Kong | 450 | 2019-07-15 | 2024-08-22 |
| A Study of Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems Azacitidine, Pevonedistat - Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic | Phase 1 | Completed | Takeda | 17 | 2019-07-10 | 2024-09-05 |
| Elafibranor Pharmacokinetic Parameters in Hepatic Impaired Patients Elafibranor - Hepatic Impairment, Liver Disease | Phase 1 | Completed | Genfit | 30 | 2018-12-12 | 2019-08-22 |
| Estimation of Minimum Efficacy Daily Dose of Jarlsberg Cheese Jarlsberg cheese - Heathy Women, Pre Menopausal Age | Not applicable | Completed | Prof Stig Larsen | 20 | 2018-09-01 | 2023-01-11 |
| Treatment of Chronic Delta Hepatitis With Lonafarnib, Ritonavir and Lambda Interferon Peg-interferon lambda, Lonafarnib, Ritonavir - Liver Disease, Hepatitis D | Phase 2 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 26 | 2018-08-01 | 2021-12-14 |
| Inhibition of VAP-1 by Caffeine in Healthy Human Volunteers Study Caffeine citrate - Liver Disease | Phase 1 | Withdrawn | University of Birmingham | 2018-03-01 | 2018-04-19 | |
| deLIVER: Direct Acting Antiviral Effects on the Liver Sofosbuvir/Velpatasvir/Voxilaprevir [SOF/VEL/VOX], Sofosbuvir/Velpatasvir (SOF/VEL) - HCV Coinfection, Liver Disease | Phase 4 | Completed | Johns Hopkins University | 15 | 2017-01-01 | 2022-02-24 |
| Controlled Attenuation Parameter (CAP) in Liver Allografts Fibroscan 402/530 - Liver Transplant, Liver Steatosis | Completed | Andres Duarte-Rojo | 160 | 2016-09-07 | 2020-07-31 | |
| Enteral Fish Oil is Superior to Ursodeoxycholic Acid (UDCA) and Placebo for the Treatment of Cholestasis in Infants Enteral fish oil, Ursodeoxycholic Acid, Placebo - Cholestasis, Liver Disease | Phase 2 | Withdrawn | The University of Texas Health Science Center at San Antonio | 2016-06-01 | 2016-06-21 | |
| Correlation and Comparison of the HepQuant® Disease Severity Index (DSI) With Hepatic Venous Pressure Gradient (HVPG) HepQuant-SHUNT (Drug and Device) #65,123 (4D-cholate) and IND #65,121 (13C-cholate), Hepatic Venous Pressure Gradient (HVPG) - Liver Disease | Phase 3 | Completed | University of Colorado, Denver | 20 | 2016-03-01 | 2021-08-09 |
| Effect of Synbiotic on Postoperative Complications After Liver Transplantation Synbiotic, Control - Liver Disease | Not applicable | Unknown | Hospital de Clinicas de Porto Alegre | 76 | 2016-03-01 | 2016-10-19 |
| Minocycline Administration During Human Liver Transplantation Minocycline (yes/no), Placebo - Liver Disease | Phase 4 | Withdrawn | Medical University of South Carolina | 2016-03-01 | 2018-06-18 | |
| Oral Hepatitis C Treatment for Indolent Lymphoma (OPTImaL) Study sofosbuvir/ledipasvir, sofosbuvir, Ribavirin - Liver Disease | Phase 4 | Terminated | University of Texas Southwestern Medical Center | 1 | 2016-02-25 | 2019-01-08 |
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Liver Diseases (123) · Hepatitis C (10) · Fibrosis (8) · Kidney Diseases (7) · Non-alcoholic Fatty Liver Disease (7) · Liver Cirrhosis (6) · Cholestasis (5) · Alcoholism (4) · Carcinoma, Hepatocellular (4) · Fatty Liver (4) · Hepatitis B (4) · Diabetes Mellitus (3) · Heart Diseases (3) · Heart Failure (3) · Hepatitis C, Chronic (3)
Digestive System Diseases (121) · Pathological Conditions, Signs and Symptoms (39) · Pathologic Processes (31) · Infections (20) · Virus Diseases (16) · RNA Virus Infections (14) · Blood-Borne Infections (13) · Communicable Diseases (13) · Hepatitis, Viral, Human (13) · Hepatitis (12) · Signs and Symptoms (12) · Flaviviridae Infections (11) · Nutritional and Metabolic Diseases (10) · Urogenital Diseases (10) · Female Urogenital Diseases (9)
Ribavirin (4) · Tacrolimus (4) · Hepatectomy (3) · Blood Specimen Collection (2) · Mycophenolic Acid (2) · Propofol (2) · Sofosbuvir (2) · Ursodeoxycholic Acid (2) · alisporivir (2) · conivaptan (2) · fish oil triglycerides (2) · 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid (1) · 4-((1,4,8,11-tetraazacyclotetradec-1-yl)methyl)benzoic acid (1) · Alemtuzumab (1) · Anesthesia, Conduction (1)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (8) · Federal University of Minas Gerais (3) · National Institute of Allergy and Infectious Diseases (NIAID) (3) · National Taiwan University Hospital (3) · Cumberland Pharmaceuticals (2) · Debiopharm International SA (2) · Helse Nord-Trøndelag HF (2) · Johns Hopkins Bloomberg School of Public Health (2) · Maastricht University Medical Center (2) · Medical University of South Carolina (2) · Rutgers, The State University of New Jersey (2) · Samsung Medical Center (2) · The University of Texas Health Science Center at San Antonio (2) · University of California, San Francisco (2) · University of Chicago (2)
United States (62) · United Kingdom (7) · Brazil (5) · France (5) · China (4) · Germany (4) · Belgium (3) · Canada (3) · Israel (3) · Netherlands (3) · Norway (3) · South Korea (3) · Switzerland (3) · Taiwan (3) · Italy (2)
Art Wheeler, MD (2) · Baburao Koneru, M.D. (2) · Yaron Rotman, M.D. (2) · Aldo Torre Delgadillo, M.D., M. Sc. (1) · Alessandra Mangia, MD (1) · Amanda Wieland, MD (1) · Amy Pollack, MD (1) · Andres Duarte-Rojo, MD (1) · Antonio Daniele Pinna, MD (1) · Asuncion Moreno, MD (1) · Babuaro Koneru, MD (1)
PMID 12149596, PMID 15888204, PMID 16003227, PMID 16029225, PMID 16539632, PMID 16628690, PMID 16850377, PMID 16970840, PMID 17058231, PMID 17195325, PMID 17611251, PMID 17635375, PMID 17876267, PMID 17949458, PMID 17949460, PMID 18031464, PMID 19059920, PMID 19268724, PMID 19281442, PMID 19298451, PMID 19776780, PMID 19800334, PMID 19940946, PMID 20005373, PMID 20346065, PMID 20921898, PMID 21083386, PMID 21092252, PMID 21535051, PMID 21680855, PMID 21810825, PMID 22030902, PMID 22410036, PMID 22510354, PMID 22521347, PMID 22559239, PMID 22563020, PMID 22647561, PMID 22759736, PMID 22762561, PMID 22858882, PMID 22938898, PMID 23290631, PMID 23492964, PMID 23512786, PMID 23625132, PMID 23714349, PMID 23739141, PMID 23828202, PMID 24030928
U01DK061730 (2), 2008 (1), 2018 (1), R01DK058763 (1), R01DK066368 (1), R03DK055618 (1), U01AI052748 (1), UL1TR001082 (1)