55 completed, 30 unknown, 7 not yet recruiting, 7 recruiting. 30 Not applicable, 12 Phase 2, 6 Phase 3, 4 Phase 4, 2 Phase 1.
Follow Hepatectomy: new trials by email Literature Review of Hepatectomy trials Research Report on Hepatectomy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| HRX215, A First Generation MKK4 Inhibitor Drug, for the Treatment of Patients With Colorectal Liver Metastasis After Undergoing a Portal Vein Embolization Biopsy Procedure, Biospecimen Collection, Computed Tomography - Metastatic Colorectal Carcinoma, Metastatic Malignant Neoplasm in the Liver | Phase 2 | Not yet recruiting | Mayo Clinic | 80 | 2026-12-01 | 2026-10-05 |
| TRANsplantation vs reSECTion After Conversion Therapy for Initially Unresectable Colorectal Liver Metastases Liver Transplantation, Liver Resection plus Ablation - Colorectal Liver Metastases | Not applicable | Recruiting | Niguarda Hospital | 70 | 2026-06-01 | 2026-07-17 |
| Prospective Clinical Database Construction for Liver Cancer Diagnosis and Treatment liver resection, Systemic therapy combined with locoregional interventions - Liver Cancer (Primary and Metastatic) | Recruiting | Tongji Hospital | 800 | 2026-01-01 | 2026-06-04 | |
| Evaluation Of Liver Resection Using Harmonic Scalpel Versus Cavitron Ultrasonic Surgical Aspirator (CUSA). Liver resection Cavitron Ultrasonic Surgical Aspirator (CUSA), Liver resection with the harmonic scalpel - Liver Resection, Liver Tumours | Not applicable | Not yet recruiting | Sohag University | 50 | 2025-08-22 | 2025-08-27 |
| NON-COlorectal Liver METastases Undergoing Liver Resection liver resection - Liver Metastases | Not yet recruiting | Azienda Ospedaliero Universitaria Maggiore della Carita | 300 | 2025-01-01 | 2024-08-07 | |
| Neoadjuvant Therapy in Patients With Resectable HCC Screened by a Multimodal Deep Learning Model Hepatic arterial infusion chemotherapy, Lenvatinib, Tislelizumab - HCC | Phase 2 | Recruiting | Chen Xiaoping | 160 | 2024-06-01 | 2025-05-01 |
| Efficacy and Safety of Neoadjuvant Therapy in Patients With Resectable HCC Screened by a Multimodal Deep Learning Model. HAIC + Tirelizumab +lenvatinib +liver resection, liver resection - HCC | Phase 4 | Not yet recruiting | Chen Xiaoping | 312 | 2024-05-01 | 2024-03-15 |
| Liver Resection and Simultaneous Sleeve Gastrectomy for MS-HCC (LIRESS) Liver resection and simultaneous sleeve gastrectomy for HCC induced by metabolic syndrome, Liver resection for HCC induced by metabolic syndrome - Carcinoma, Hepatocellular, Metabolic Syndrome | Not applicable | Not yet recruiting | Ospedale V. Fazzi | 50 | 2024-03-06 | 2023-12-19 |
| Precision Recurrence Risk Assessment in Early-stage Hepatocellular Carcinoma liver resection - Hepatocellular Carcinoma (HCC) | Completed | Tongji Hospital | 579 | 2023-08-25 | 2025-06-29 | |
| FOLFOX-HAIC as Conversion Treatment for Initially Unresectable Colorectal Liver Metastasis FOLFOX (oxaliplatin, leucovorin, 5-fluorouracil [5FU]), hepatic arterial infusion chemotherapy (HAIC), Bevacizumab - Colorectal Liver Metastasis (CRLM) | Phase 2 | Recruiting | Tongji Hospital | 300 | 2023-05-01 | 2025-05-25 |
| Effect of Hepatectomy on the Prognosis of Patients With Nasopharyngeal Carcinoma Liver Metastases Hepatectomy - Nasopharyngeal Carcinoma, Liver Metastases | Not applicable | Unknown | Fudan University | 55 | 2023-04-01 | 2023-05-19 |
| Image Driven Hepatocellular Carcinoma Invasiveness Evaluation Research Hepatectomy - Hepatocellular Carcinoma Stage III | Recruiting | Chinese PLA General Hospital | 500 | 2023-01-01 | 2024-08-19 | |
| Clinical Study of MRD Recurrence Monitoring After Surgical Resection of Hepatocellular Carcinoma Liver resection - HCC | Unknown | Anhui Provincial Hospital | 200 | 2022-09-30 | 2022-07-14 | |
| Surgical Approach for Adenocarcinoma of the Pancreas With Synchronous Liver Metastases Pancreatectomy and liver resection, Chemotherapy - Pancreas Neoplasms, Liver Metastasis | Completed | Azienda Ospedaliero-Universitaria di Modena | 90 | 2022-06-01 | 2025-05-20 | |
| TACE/HAIC Combined With Lenvatinib and Sintilimab in Neoadjuvant Therapy for Intermediate-stage HCC TACE/HAIC, Lenvatinib, Sintilimab - Hepatocellular Carcinoma | Phase 2 / Phase 3 | Unknown | Third Affiliated Hospital, Sun Yat-Sen University | 90 | 2022-05-30 | 2023-10-13 |
| Watch and Wait and Surgical Treatment for Clinical Complete Responders After Non-Curative Therapy for Hepatocellular Carcinoma Liver Resection - Hepatocellular Carcinoma | Phase 2 | Completed | Sun Yat-sen University | 74 | 2022-05-05 | 2026-01-15 |
| Surgery for Liver Metastases From PDAC Liver resection (ablation) - Disseminated Pancreatic Cancer | Not applicable | Not yet recruiting | Linkoeping University | 64 | 2022-03-01 | 2022-03-08 |
| Surgical Resection for Hepatocellular Carcinoma Liver Resection - Resectable Hepatocellular Carcinoma | Completed | Dr Cipto Mangunkusumo General Hospital | 91 | 2021-12-01 | 2023-08-28 | |
| Validation of the Classification for Resectability and Ablatability Criteria for the Treatment of Liver Only Colorectal Metastases Liver resection - Colorectal Adenocarcinoma Metastatic in the Liver | Completed | University Hospital, Linkoeping | 116 | 2021-11-01 | 2026-05-06 | |
| EXtended CriteriA Treatment for LIver Metastases and Heavy Tumour BURden Liver-resection or ablation, 2nd line chemotherapy - Liver Metastases, Colorectal Cancer | Phase 2 | Suspended | Oslo University Hospital | 62 | 2021-03-23 | 2026-10-22 |
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Carcinoma, Hepatocellular (42) · Liver Neoplasms (13) · Colorectal Neoplasms (11) · Cholangiocarcinoma (6) · Recurrence (6) · Liver Diseases (5) · Neoplasm Metastasis (5) · Fibrosis (4) · Colonic Neoplasms (3) · Pancreatic Neoplasms (3) · Postoperative Complications (3) · Hypertension, Portal (2) · Liver Failure (2) · Rupture, Spontaneous (2) · Abdominal Injuries (1)
Sun Yat-sen University (8) · University of Milan (8) · Tongji Hospital (6) · Chen Xiaoping (4) · Chinese PLA General Hospital (3) · Eastern Hepatobiliary Surgery Hospital (3) · First Affiliated Hospital, Sun Yat-Sen University (3) · Huazhong University of Science and Technology (3) · Humanitas Clinical and Research Center (3) · Southwest Hospital, China (3) · Azienda Ospedaliero Universitaria Maggiore della Carita (2) · Beaujon Hospital (2) · Memorial Sloan Kettering Cancer Center (2) · Oslo University Hospital (2) · Sohag University (2)
China (35) · Italy (12) · France (8) · United States (8) · United Kingdom (6) · Austria (2) · Germany (2) · Hong Kong (2) · Norway (2) · South Korea (2) · Spain (2) · Sweden (2) · Switzerland (2) · Taiwan (2) · Canada (1)
Guido Torzilli, MD, PhD (3) · Matteo Donadon, MD, PhD (3) · Shen Feng, MD (2) · Abdelkader Belkouchi, MD (1) · Andrea Cercek, MD (1) · Annarita Libia (1) · Baogang Peng, MD (1) · Bi-xiang Zhang, Prof, PHD (1) · Charing CN Chong, MBChB (1) · Chloe Atreya, MD, Ph.D. (1) · Christine Bernsmeier, PD Dr. Dr. (1) · Daniel Azoulay, MD PhD (1)
PMID 19541011, PMID 12143206, PMID 14762851, PMID 15915370, PMID 16183489, PMID 16269386, PMID 16953487, PMID 18362622, PMID 19094562, PMID 19300227, PMID 19858707, PMID 19942479, PMID 20137393, PMID 20409520, PMID 20632273, PMID 20799289, PMID 21975322, PMID 22359112, PMID 23269991, PMID 23360920, PMID 23426336, PMID 23874536, PMID 23880068, PMID 23943100, PMID 24277679, PMID 24585720, PMID 25217112, PMID 25243564, PMID 26148518, PMID 26330348, PMID 27724929, PMID 28083837, PMID 28192187, PMID 28406940, PMID 28585106, PMID 28842294, PMID 28935451, PMID 29140542, PMID 29149975, PMID 29254263, PMID 29373365, PMID 30003350, PMID 30401520, PMID 30701365, PMID 30704966, PMID 31851740, PMID 32399263, PMID 33102398, PMID 34688256, PMID 35383076
R01DK079879 (1), R01DK140085 (1)