7 completed, 3 withdrawn, 2 terminated, 2 unknown. 14 Phase 2, 4 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 14 | Completed 7, Withdrawn 3, Terminated 2, Unknown 2 |
| Phase 1 | 4 | Completed 1, Terminated 1, Unknown 1, Withdrawn 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Liver Disease: new trials by email Literature Review of Liver Disease trials Research Report on Liver Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Alternate Dosing Study of MK-6024 in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) (MK-6024-016) Efinopegdutide - Metabolic Dysfunction-Associated Steatotic Liver Disease, Non-alcoholic Fatty Liver Disease | Phase 2 | Completed | Merck Sharp & Dohme LLC | 124 | 2024-07-29 | 2026-06-01 |
| Treatment of Chronic Delta Hepatitis With Lonafarnib, Ritonavir and Lambda Interferon Peg-interferon lambda, Lonafarnib, Ritonavir - Liver Disease, Hepatitis D | Phase 2 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 26 | 2018-08-01 | 2021-12-14 |
| Enteral Fish Oil is Superior to Ursodeoxycholic Acid (UDCA) and Placebo for the Treatment of Cholestasis in Infants Enteral fish oil, Ursodeoxycholic Acid, Placebo - Cholestasis, Liver Disease | Phase 2 | Withdrawn | The University of Texas Health Science Center at San Antonio | 2016-06-01 | 2016-06-21 | |
| Clinical Study of Lyophilized Plasma in Patients With Liver Disease Lyophilized Plasma, Licensed Plasma - Liver Disease | Phase 2 | Withdrawn | HemCon Medical Technologies, Inc | 2015-01-01 | 2015-03-18 | |
| Alisporivir With RBV in Chronic Hepatitis C Genotype 2 and 3 Participants for Whom Interferon is Not an Option Alisporivir, Ribavirin - Hepatitis C, Liver Disease | Phase 2 | Completed | Debiopharm International SA | 52 | 2014-03-01 | 2016-10-13 |
| Investigational Study of Oral Fish Oil in Treating Parenteral Nutrition Associated Liver Disease Lovaza (omega-3-acid ethyl ester), Corn oil - Liver Disease, Short Bowel Syndrome | Phase 1 / Phase 2 | Withdrawn | Boston Children's Hospital | 2011-01-01 | 2017-06-22 | |
| Human Menstrual Blood-derived Mesenchymal Stem Cells for Patients With Liver Cirrhosis conventional therapy plus MenSC transplantation, Conventional therapy plus placebo treatment - Liver Cirrhosis, Fibrosis | Phase 1 / Phase 2 | Unknown | S-Evans Biosciences Co., Ltd. | 50 | 2010-10-01 | 2012-06-07 |
| Immunity Against Varicella in Pediatric Orthotopic Liver Transplantation Recipients Vaccination with VZV vaccine - Liver Disease, Immunosuppression | Phase 2 / Phase 3 | Unknown | University Hospital, Geneva | 80 | 2007-06-01 | 2020-09-18 |
| Study to Assess the Safety, Tolerability, and Pharmacodynamics of RTA 402 in Patients With Hepatic Dysfunction RTA 402 - Liver Disease | Phase 1 / Phase 2 | Terminated | Biogen | 16 | 2007-04-30 | 2025-05-30 |
| Phase 2 Study of PEG-Intron in Hereditary Hemorrhagic Telangiectasia Pegylated Interferon Alpha2b, Standard care - Anemia, Liver Disease | Phase 2 | Terminated | Mayo Clinic | 10 | 2007-01-01 | 2013-02-22 |
| A Phase I/II Safety and Tolerability Dose Escalation Study of Autologous Stem Cells to Patients With Liver Insufficiency Autologous Expanded CD34+ Haemopoietic cells - Liver Disease | Phase 1 / Phase 2 | Completed | Imperial College London | 5 | 2006-01-01 | 2019-10-31 |
| Immune System Suppression With Alemtuzumab and Tacrolimus in Liver Transplantation Patients Alemtuzumab, Cyclosporine, Mycophenolate mofetil - Liver Disease, Liver Transplantation | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 27 | 2005-06-01 | 2012-12-27 |
| Pegylated Interferon Alfa-2a Maintenance Therapy and Liver Disease Progression in People Infected With Both HIV and Hepatitis C Virus (HCV) Peginterferon alfa-2a, Ribavirin - HIV Infections, Hepatitis C | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 333 | 2004-07-01 | 2021-11-08 |
| A Phase II Study of DMP 115 to Assess Focal Liver Lesions Peflutren Lipid Microsphere Injectable Suspension - Liver Disease | Phase 2 | Completed | Lantheus Medical Imaging | 80 | 2004-03-01 | 2011-08-18 |
Liver Diseases (14) · Fibrosis (2) · Hepatitis C (2) · Anemia (1) · Anemia, Iron-Deficiency (1) · Chickenpox (1) · Cholestasis (1) · Digestive System Diseases (1) · HIV Infections (1) · Hepatitis D (1) · Hypoxia (1) · Liver Cirrhosis (1) · Non-alcoholic Fatty Liver Disease (1) · Rejection, Psychology (1) · Short Bowel Syndrome (1)
Digestive System Diseases (13) · Infections (4) · Pathological Conditions, Signs and Symptoms (4) · Virus Diseases (4) · Hepatitis (3) · Hepatitis, Viral, Human (3) · Pathologic Processes (3) · RNA Virus Infections (3) · Blood-Borne Infections (2) · Communicable Diseases (2) · Flaviviridae Infections (2) · Anemia, Hypochromic (1) · Behavior (1) · Bile Duct Diseases (1) · Biliary Tract Diseases (1)
Ribavirin (2) · Ursodeoxycholic Acid (2) · Alemtuzumab (1) · Corn Oil (1) · Cyclosporine (1) · Fish Oils (1) · Interferons (1) · Liver Transplantation (1) · Mycophenolic Acid (1) · Omacor (1) · Ritonavir (1) · Standard of Care (1) · Tacrolimus (1) · Vaccination (1) · alisporivir (1)
National Institute of Allergy and Infectious Diseases (NIAID) (2) · Biogen (1) · Boston Children's Hospital (1) · Debiopharm International SA (1) · HemCon Medical Technologies, Inc (1) · Imperial College London (1) · Lantheus Medical Imaging (1) · Mayo Clinic (1) · Merck Sharp & Dohme LLC (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · S-Evans Biosciences Co., Ltd. (1) · The University of Texas Health Science Center at San Antonio (1) · University Hospital, Geneva (1)
United States (9) · Puerto Rico (2) · United Kingdom (2) · Canada (1) · China (1) · France (1) · Switzerland (1)
Charlie Xiang, Professor (1) · Christopher Koh, M.D. (1) · Cynthia Blanco, M.D. (1) · Edward L.S. Leen, MD (1) · J. Richard Thistlethwaite, MD (1) · Karen L Swanson, DO (1) · Kenneth E. Sherman, MD, PhD (1) · Klara M Posfay-Barbe, MD, MS (1) · Nagy Habib, ChM FRCS (1) · Raymond Chung, MD (1) · Thomas C. Marbury, MD (1) · Tom Jaksic, MD, PhD (1)
PMID 19268724, PMID 20921898, PMID 21535051, PMID 22510354, PMID 22563020, PMID 23739141