12 completed, 2 recruiting, 2 terminated, 2 unknown. 11 Not applicable, 2 Phase 1, 2 Phase 2, 2 Phase 3, 1 Phase 4.
Follow Leg Ulcers: new trials by email Literature Review of Leg Ulcers trials Research Report on Leg Ulcers
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Modified Platform Trial Assessing Multiple Umbilical Cord-based CAMPs and SOC v SOC Alone in the Treatment of Hard-to-Heal VLUs Standard of Care (SOC), Corplex P, Theracor - Venous Leg Ulcers, Venous Leg Ulcers (VLUs) | Not applicable | Not yet recruiting | StimLabs | 272 | 2026-07-01 | 2026-03-04 |
| Efficacy of Human Placental Membrane Products and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers Tri-Membrane Wrap™ DFU, Membrane Wrap™ DFU, Membrane Wrap-Lite™ DFU - Diabetic Foot Ulcer, Foot Ulcer Chronic | Not applicable | Recruiting | BioLab Holdings | 50 | 2026-01-02 | 2026-10-01 |
| Efficacy and Safety of Light Compression System in the Local Treatment of Mixed Leg Ulcers (PROMETHEE Clinical Investigation) Treatment with light compression systeme during 16-week treatment period (6 medical visits are planned: D0, W2, W4, W8, W12, W16), Light compression system of the mixed leg ulcer stage C6 / C6r of the CEAP classification - Leg Ulcers | Not applicable | Recruiting | Laboratoires URGO | 210 | 2025-03-29 | 2025-04-08 |
| Vacuum Compression Therapy for Chronic Lower Limb Ulcers Vacuum Compression Therapy (VCT), Standardized Wound Care - Leg Ulcers, Diabetic Foot Ulcer | Not applicable | Completed | BTL Industries Ltd. | 50 | 2024-07-01 | 2026-08-03 |
| Resolution of Sickle Cell Leg Ulcers With Voxelotor Voxelotor Oral Tablet, Placebo - Sickle Cell Disease, Leg Ulcers | Phase 3 | Terminated | Pfizer | 88 | 2022-05-30 | 2025-07-09 |
| Physical Activity Interventions for Leg Ulcer Patients FOOTFIT - Leg Ulcers, Venous Ulcers | Not applicable | Completed | Medical University of South Carolina | 24 | 2015-04-01 | 2018-09-07 |
| Assessment of Efficacy & Safety for a New Wound Dressing Urgo 310 3166 in the Local Treatment of VLU or Mixed Leg Ulcers Urgo 3103166, Aquacel Extra - Leg Ulcers | Not applicable | Unknown | Laboratoires URGO | 2014-10-01 | 2015-10-22 | |
| Compare Aquacel® Ag Versus Mepilex® Border Ag to Manage Bioburden in Leg Ulcers Aquacel® Ag, Mepilex® Border Ag - Leg Ulcers | Phase 3 | Completed | ConvaTec Inc. | 18 | 2011-08-01 | 2013-07-30 |
| Physiotulle vs Urgotul in the Treatment of Leg Ulcer Physiotulle, URGOTUL - Leg Ulcers | Phase 4 | Completed | Coloplast A/S | 188 | 2009-11-01 | 2011-09-05 |
| A Clinical Trial on Diabetic Foot Using Peripheral Blood Derived Stem Cells for Treating Critical Limb Ischemia will receive G-CSF and peripheral blood derived mononuclear cells, G-CSF, Standard Therapy - Diabetic Foot, Critical Limb Ischemia | Phase 1 / Phase 2 | Unknown | Beike Biotech India Pvt.ltd | 36 | 2009-07-01 | 2009-06-17 |
| Biatain Ag vs Biatain in the Treament of Leg Ulcers Biatain Ag, Biatain - Leg Ulcers | Not applicable | Completed | Coloplast A/S | 182 | 2008-12-01 | 2018-01-16 |
| The AutoloGel™ Post-Market Surveillance (TAPS) Program AutoloGel System - Wounds, Leg Ulcers | Not applicable | Terminated | Cytomedix | 131 | 2008-09-01 | 2014-02-26 |
| Safety Evaluation of Biatain Ibu in Painful Chronic Venous Leg Ulcers Biatain Ibu, Local best practice - Leg Ulcers | Not applicable | Completed | Coloplast A/S | 93 | 2008-05-01 | 2017-04-26 |
| Potential Research Study Participant Registry Acne, Actinic Keratosis | Completed | University of California, Davis | 265 | 2008-05-01 | 2019-02-15 | |
| Biatain Ibu vs. Biatain in Painful Chronic Venous Leg Ulcers Biatain, Biatain Ibu - Leg Ulcers | Not applicable | Completed | Coloplast A/S | 120 | 2008-03-01 | 2017-09-15 |
| CLUE Study: Connective Tissue Disease Leg Ulcer Etiology Study Connective Tissue Diseases, Blood Coagulation Disorders | Completed | George Washington University | 40 | 2007-08-01 | 2017-08-30 | |
| Compression Device Versus 4-layer Compression System Compression Device, Profore - Leg Ulcers | Phase 2 | Completed | ConvaTec Inc. | 90 | 2006-05-01 | 2015-01-09 |
| Legtest Multi Centre Testing of the Lively Legs Program for Promoting Compliance in Leg Ulcer Patients Health Counseling - Leg Ulcers, Varicose Ulcers | Not applicable | Completed | Radboud University Medical Center | 180 | 2005-01-01 | 2010-02-09 |
| Bioengineered Skin and Wound Healing Bioengineered skin - Leg Ulcers | Phase 1 | Completed | Roger Williams Medical Center | 50 | 2000-10-01 | 2013-08-02 |
Leg Ulcer (19) · Varicose Ulcer (6) · Diabetic Foot (4) · Foot Ulcer (2) · Ulcer (2) · Acne Vulgaris (1) · Anemia, Sickle Cell (1) · Arthritis, Rheumatoid (1) · Blood Coagulation Disorders (1) · Chronic Limb-Threatening Ischemia (1) · Connective Tissue Diseases (1) · Dermatitis, Atopic (1) · Diabetes Complications (1) · Dysplastic Nevus Syndrome (1) · Eczema (1)
Skin Diseases (19) · Skin and Connective Tissue Diseases (19) · Skin Ulcer (18) · Cardiovascular Diseases (8) · Vascular Diseases (8) · Varicose Veins (6) · Diabetes Mellitus (4) · Diabetic Angiopathies (4) · Diabetic Neuropathies (4) · Endocrine System Diseases (4) · Diabetes Complications (3) · Foot Ulcer (3) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2)
Standard of Care (2) · Granulocyte Colony-Stimulating Factor (1) · Intermittent Pneumatic Compression Devices (1) · Therapeutics (1) · voxelotor (1)
Coloplast A/S (4) · ConvaTec Inc. (2) · Laboratoires URGO (2) · BTL Industries Ltd. (1) · Beike Biotech India Pvt.ltd (1) · BioLab Holdings (1) · Cytomedix (1) · George Washington University (1) · Medical University of South Carolina (1) · Pfizer (1) · Radboud University Medical Center (1) · Roger Williams Medical Center (1) · StimLabs (1) · University of California, Davis (1)
United States (6) · France (5) · Denmark (3) · Germany (3) · Spain (2) · United Kingdom (2) · Brazil (1) · Czechia (1) · India (1) · Ireland (1) · Kenya (1) · Netherlands (1) · Nigeria (1)
Karsten Fogh, MD (2) · Dr. Anoop Misra, MD (1) · Fu-Tong Liu, M.D., Ph.D. (1) · Gregory H Szeyko, MD (1) · Janaki Nadarajah, DPM (1) · John G Martinez, MD (1) · Jonathon Hopper, MD (1) · Keith Harding (1) · Macy G Hall, MD (1) · Moby Madisetti, MS (1) · Sylvie Meaume, MD (1)
R01AR046557 (1)