6 recruiting, 3 completed, 2 not yet recruiting, 2 unknown. 15 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 15 | Recruiting 6, Completed 3, Not yet recruiting 2, Unknown 2, Active not recruiting 1, Withdrawn 1 |
Follow Left Bundle Branch Area Pacing: new trials by email Literature Review of Left Bundle Branch Area Pacing trials Research Report on Left Bundle Branch Area Pacing
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Comparison of Left Bundle Branch Optimized Cardiac Resynchronization Therapy vs Left Bundle Branch Area Pacing Alone LOT-CRT-P (Programming: LBBAP), LOT-CRT-P (Programming: LOT-CRT-P) - Heart Failure, Left Bundle Branch Area Pacing | Not applicable | Not yet recruiting | PD Dr. Guram Imnadze | 124 | 2027-02-01 | 2026-09-25 |
| Transesophageal Echocardiography in Conductive System Pacing in Pediatric Patients Left Bundle Branch Pacing - Left Bundle Branch Area Pacing | Not applicable | Not yet recruiting | Assiut University | 56 | 2026-12-01 | 2026-10-20 |
| Safety and Performances of the LINEA Cardiac Pacing Lead Optimized for the Implantation in Interventricular Septum Use of LINEA cardiac pacing lead - Bradycardia, Left Bundle Branch Area Pacing | Not applicable | Recruiting | MicroPort CRM | 450 | 2026-06-23 | 2026-09-23 |
| Left Bundle Branch Area Pacing (LBBAP) Monitoring Assistant: Evaluation of Portable ECG Solution LBBAP implant - Bradycardia, Left Bundle Branch Area Pacing | Not applicable | Completed | MicroPort CRM | 55 | 2025-11-14 | 2026-10-30 |
| Left Bundle Branch Area Pacing (LBBAP) PMCF Study LBBAP lead - Bradycardia, Right Ventricular Pacing | Not applicable | Recruiting | Abbott Medical Devices | 200 | 2025-07-24 | 2026-09-25 |
| Safety and Performance Evaluation of a New Catheter Range for Lead Implantation at Interventricular Septum Use of FLEXIGO delivery catheter - Bradycardia, Cardiac Resynchronization Therapy | Not applicable | Completed | MicroPort CRM | 216 | 2025-02-14 | 2026-09-23 |
| Left Bundle Branch Area Pacing in Patients With Heart Failure left bundle branch area pacing - Heart Failure With Reduced Ejection Fraction, Left Bundle Branch Area Pacing | Not applicable | Unknown | National Research Center for Cardiac Surgery, Kazakhstan | 50 | 2024-06-01 | 2024-07-05 |
| UHF ECG in LBBB and Response to CRT Prediction LBBAP CRT device implantation, BVP-CRT - Left Bundle Branch Block, Left Bundle Branch Area Pacing | Not applicable | Recruiting | Faculty Hospital Kralovske Vinohrady | 200 | 2024-05-01 | 2025-07-14 |
| The Impact of LBBAP vs RVP on the Incidence of New-onset Atrial Fibrillation in Patients With Atrioventricular Block left bundle branch area pacing, right ventricular pacing - Left Bundle Branch Area Pacing, Right Ventricular Pacing | Not applicable | Recruiting | Peking Union Medical College Hospital | 530 | 2023-09-30 | 2026-09-21 |
| "Physiological vs Right Ventricular Pacing Outcome Trial Evaluated for bradyCardia Treatment" (PROTECT-HF) Pacemaker - Physiological pacing, Pacemaker - Right Ventricular pacing - Bradycardia, Pacing | Not applicable | Recruiting | Imperial College London | 2600 | 2023-06-05 | 2026-07-22 |
| The Boston Pace Study Left Bundle Branch Area Pacemaker, Right Ventricular Pacemaker - Left Bundle Branch Area Pacing | Not applicable | Active not recruiting | Massachusetts General Hospital | 100 | 2023-05-01 | 2026-07-13 |
| Evaluation of Left Bundle Branch Area Pacing As A Rescue Strategy for Cardiac Resynchronization Therapy Non-Response Left bundle branch area pacing, Cardiac MRI - Systolic Heart Failure, Heart Failure With Reduced Ejection Fraction | Not applicable | Withdrawn | VA Office of Research and Development | 2023-04-30 | 2025-08-11 | |
| PReventive Effect Of Left Bundle Branch Area Pacing Versus righT vEntricular paCing on All Cause deaTh, Heart Failure Progression, and Ventricular dysSYNChrony in Patients With Substantial Ventricular Pacing (PROTECT-SYNC): Multicenter Prospective Randomized Controlled Trial Left bundle branch area pacing, Right ventricular pacing - Bradyarrhythmia, Atrioventricular Block | Not applicable | Recruiting | Yonsei University | 450 | 2022-11-01 | 2026-01-05 |
| Clinical Efficacy of Left Bundle Branch Area Pacing for Patients With Permanent Atrial Fibrillation and Heart Failure Left bundle branch area pacing, Biventricular pacing - Left Bundle Branch Area Pacing, Biventricular Pacing | Not applicable | Unknown | Fu Wai Hospital, Beijing, China | 60 | 2022-07-18 | 2024-01-10 |
| Impact of Left Bundle Branch Area Pacing vs. Right Ventricular Pacing in Atrioventricular Block (LEAP-Block) Left bundle branch area pacing, Right ventricular pacing - Atrioventricular Block, Left Bundle Branch Area Pacing | Not applicable | Completed | Fu Wai Hospital, Beijing, China | 486 | 2020-11-13 | 2025-12-30 |
Heart Failure (7) · Bradycardia (6) · Atrioventricular Block (3) · Atrial Fibrillation (2) · Bundle-Branch Block (2) · Heart Diseases (1) · Heart Failure, Systolic (1)
Cardiovascular Diseases (13) · Heart Diseases (12) · Arrhythmias, Cardiac (10) · Pathologic Processes (10) · Pathological Conditions, Signs and Symptoms (10) · Cardiac Conduction System Disease (5) · Heart Block (5)
Cardiac Resynchronization Therapy (1)
MicroPort CRM (3) · Fu Wai Hospital, Beijing, China (2) · Abbott Medical Devices (1) · Assiut University (1) · Faculty Hospital Kralovske Vinohrady (1) · Imperial College London (1) · Massachusetts General Hospital (1) · National Research Center for Cardiac Surgery, Kazakhstan (1) · PD Dr. Guram Imnadze (1) · Peking Union Medical College Hospital (1) · VA Office of Research and Development (1) · Yonsei University (1)
France (4) · China (3) · Germany (3) · Italy (3) · Spain (3) · Portugal (2) · United States (2) · Belgium (1) · Brazil (1) · Czechia (1) · India (1) · Ireland (1) · Kazakhstan (1) · Malaysia (1) · Singapore (1)
Dr Pierre- Antoine Catalan (1) · Mahmoud Abdelsabour, Professor (1) · Selma D Carlson, MD (1) · TaeHoon Kim (1) · Taibo Chen, PhD. (1) · Xiaohan Fan, PhD (1) · Xiaohan Fan, PhD. (1) · Yerlan Turubayev, MD (1)