8 completed, 2 unknown, 2 withdrawn, 1 not yet recruiting. 14 Phase 2, 2 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 14 | Completed 8, Unknown 2, Withdrawn 2, Not yet recruiting 1, Terminated 1 |
| Phase 1 | 2 | Completed 1, Withdrawn 1 |
| Phase 3 | 1 | Terminated 1 |
Follow Lacerations: new trials by email Literature Review of Lacerations trials Research Report on Lacerations
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Pain Management After Surgery When Using Nerve Blocks in the Pediatric Population Ropivacaine 0.2% Injectable Solution - Anterior Cruciate Ligament (ACL) Tear, Sports Injuries in Children | Phase 2 | Not yet recruiting | Texas Scottish Rite Hospital for Children | 160 | 2025-09-01 | 2025-09-16 |
| Clinical Efficacy of Exosome in Degenerative Meniscal Injury SF-MSC-EX, SF-MSC - Knee; Injury, Meniscus (Lateral) (Medial), Meniscus Tear | Phase 2 | Unknown | Eskisehir Osmangazi University | 30 | 2022-03-01 | 2022-03-04 |
| A Single Dose Pharmaco-Diagnostic for Peripheral Nerve Continuity After Trauma 4-Aminopyridine, Placebo oral tablet - Nerve Injury | Phase 2 / Phase 3 | Terminated | Milton S. Hershey Medical Center | 1 | 2021-08-17 | 2022-10-18 |
| Pain Free Laceration Repairs Using Intra-nasal Ketamine Intranasal Ketamine - Laceration | Phase 2 | Completed | Evelyne D.Trottier | 42 | 2017-02-16 | 2019-12-16 |
| Safety and Efficacy Study of AL-53817 and AL-78843 Ophthalmic Solutions for Allergic Conjunctivitis AL-53817 Ophthalmic Solution, 0.1%, AL-78843 Ophthalmic Solution, 0.03%, Dexamethasone Ophthalmic Suspension, 0.1% - Allergic Conjunctivitis | Phase 2 | Completed | Alcon Research | 224 | 2014-04-01 | 2015-08-24 |
| Safety and Feasibility of ADRCs (Adipose Derived Regenerative Cells) in Patients With Grade II Hamstring Tears ADRCs prepared by investigational Celution Device, Placebo - Muscle Tear | Phase 1 / Phase 2 | Withdrawn | Cytori Therapeutics | 2014-01-01 | 2014-11-21 | |
| Early Treatment for Acute ACL Tear Kenalog or placebo, Kenalog then Placebo, Kenalog - Anterior Cruciate Ligament (ACL) Tears | Phase 2 | Completed | Cale Jacobs | 49 | 2013-03-01 | 2018-12-05 |
| Effect on Tear Functions of Pretarsal and Preseptal Techniques of Botulinum Toxin Type A Injection in Hemifacial Spasm preseptal injection of botulinum toxin type A, pretarsal injection of Botulinum toxin type A - Hemifacial Spasm | Phase 2 | Unknown | Khon Kaen University | 26 | 2012-04-01 | 2012-03-28 |
| Gluing Lacerations Utilizing Epinephrine LET - Lidocaine Epinephrine Tetracaine - Lacerations | Phase 2 | Completed | Children's Hospital of Eastern Ontario | 222 | 2011-04-01 | 2013-04-10 |
| Determination of the Optimum Delivery Route for Botulinum Toxin A in Patients With Epiphora Botulinum Toxin Type A - Epiphora | Phase 2 | Completed | Merbs, Shannath, M.D., Ph.D. | 26 | 2011-02-01 | 2012-09-12 |
| Topical Cyclosporine vs. Placebo for Epiphora Associated With Docetaxel Cyclosporine Eye Drops (Restasis), Lubricant Eye Drops (Refresh Endura™), Fluorometholone Eye Drops (FML Forte®) - Epiphora | Phase 2 | Withdrawn | M.D. Anderson Cancer Center | 2009-06-01 | 2012-08-02 | |
| Autologous Chondrocyte Transplantation For Articular Cartilage Regeneration Arthroscopic matrix encapsulated chondrocyte implantation - Tear; Knee, Cartilage, Articular | Phase 1 / Phase 2 | Completed | Instituto Nacional de Rehabilitacion | 10 | 2008-12-01 | 2017-04-12 |
| Study to Show Equivalence of DERMABOND PROTAPE to DERMABOND HVD for Wound Closure cyanoacrylate with pressure sensitive mesh, cyanoacrylate - Lacerations | Phase 2 | Completed | Ethicon, Inc. | 216 | 2007-08-01 | 2013-08-06 |
| Intranasal Ketamine for Procedural Sedation in Pediatric Laceration Repair Intranasal ketamine - Laceration | Phase 2 | Completed | Rhode Island Hospital | 45 | 2007-05-01 | 2010-07-22 |
Agnosia (2) · Lacrimal Apparatus Diseases (2) · Arthralgia (1) · Blast Injuries (1) · Breast Neoplasms (1) · Carcinoma, Non-Small-Cell Lung (1) · Conjunctivitis, Allergic (1) · Endophthalmitis (1) · Esophageal Neoplasms (1) · Head and Neck Neoplasms (1) · Hemifacial Spasm (1) · Hypersensitivity (1) · Knee Injuries (1) · Lung Neoplasms (1)
Wounds and Injuries (13) · Neurologic Manifestations (4) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Eye Diseases (3) · Nervous System Diseases (3) · Neurobehavioral Manifestations (2) · Pain (2) · Perceptual Disorders (2) · Adnexal Diseases (1) · Barotrauma (1) · Breast Diseases (1) · Bronchial Neoplasms (1) · Carcinoma, Bronchogenic (1) · Conjunctival Diseases (1)
Botulinum Toxins, Type A (2) · 4-Aminopyridine (1) · Cyclosporins (1) · Dexamethasone (1) · Fluorometholone (1) · Lubricant Eye Drops (1) · Ropivacaine (1) · Triamcinolone Acetonide (1)
Alcon Research (1) · Cale Jacobs (1) · Children's Hospital of Eastern Ontario (1) · Cytori Therapeutics (1) · Eskisehir Osmangazi University (1) · Ethicon, Inc. (1) · Evelyne D.Trottier (1) · Instituto Nacional de Rehabilitacion (1) · Khon Kaen University (1) · M.D. Anderson Cancer Center (1) · Merbs, Shannath, M.D., Ph.D. (1) · Milton S. Hershey Medical Center (1) · Rhode Island Hospital (1) · Texas Scottish Rite Hospital for Children (1)
United States (7) · Canada (2) · Mexico (1) · Thailand (1) · Turkey (Türkiye) (1)
Aldo F Izaguirre, M.D. (1) · Bita Esmaeli, MD (1) · Christian Lattermann, MD (1) · Clemente Ibarra, M.D. (1) · Enrique Villalobos, M.D. (1) · Evelyne D Trottier, MD, FRCPC (1) · Helen Colquhoun, MD (1) · James G Linakis, PhD, MD (1) · John C Elfar, MD (1) · Luis Guillermo Ibarra, M.D. (1) · Onur Uysal, AssocProfDr. (1) · Philip Wilson, MD (1) · Roger Zemek, MD FRCPC (1)
PMID 27279368, PMID 28007090, PMID 28146402, PMID 30033738, PMID 34928491, PMID 36774905, PMID 8501266