56 completed, 30 unknown, 24 recruiting, 10 active not recruiting. 93 Not applicable, 10 Phase 2, 6 Phase 3, 4 Phase 4, 2 Early Phase 1.
Follow Kidney Stone: new trials by email Literature Review of Kidney Stone trials Research Report on Kidney Stone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Heterozygous Individuals for AGXT and Kidney Stones Controlled Diet - Kidney Stone, Urolithiasis, Calcium Oxalate | Not applicable | Enrolling by invitation | University of Alabama at Birmingham | 4 | 2027-07-01 | 2026-08-31 |
| Novel Antimicrobial Solution to Prevent Infections antimicrobial irrigation - Kidney Stone, Infection | Not yet recruiting | Ohio State University | 50 | 2026-11-01 | 2026-10-23 | |
| Effect of Emergency Urinary Drainage on Subsequent PCNL Outcomes in Obstructive Urosepsis Retrograde Ureteral Stenting followed by PCNL, Percutaneous Nephrostomy followed by PCNL - Urosepsis, Kidney Stone | Not applicable | Recruiting | Beni-Suef University | 100 | 2026-10-01 | 2026-09-17 |
| Observational Approach Versus Surgical Intervention for Stones Surgery, Observation - Nephrolithiasis, Kidney Stone | Not applicable | Recruiting | Children's Hospital of Philadelphia | 1658 | 2026-08-17 | 2026-10-15 |
| Trial to Assess the Efficacy of EMPAgliflozin and Personalized Dietary Counseling for Kidney STONE Prevention Empagliflozin 10 MG, Placebo, Personalized dietary counseling - Kidney Stone, Nephrolithiasis | Phase 3 | Recruiting | Insel Gruppe AG, University Hospital Bern | 400 | 2026-07-02 | 2026-10-23 |
| Comparing Alkalinizing Agents Efficacy on Stone Risk in Patients on a Metabolically Controlled Diet Potassium citrate, Sodium bicarbonate, Litholyte - Kidney Stone | Early Phase 1 | Not yet recruiting | University of Texas Southwestern Medical Center | 15 | 2026-07-01 | 2026-02-13 |
| Standard Versus Flexible and Navigable Suction Ureteral Access Sheath in Pediatric Flexible Ureterorenoscopy for Renal Stones < 2 cm Standard Ureteral Access Sheath (Boston Scientific)., Flexible and Navigable Suction UAS (ClearPetra). - Pediatric Urolithiasis, Kidney Stone | Not applicable | Not yet recruiting | Tanta University | 60 | 2026-06-30 | 2026-07-08 |
| Effects of Virtual Reality Education on Anxiety and Learning in Patients Undergoing Urolithiasis Surgery VR Education, Two-Tier VR Education - Urolithiasis, Kidney Stone | Not applicable | Recruiting | Wei-Lin, Huang | 90 | 2026-06-28 | 2026-07-16 |
| Multimodal Opioid-Free Anesthesia in RIRS Dexmedetomidine-Ketamine Opioid-Free Anesthesia, Fentanyl-Based Anesthesia - Kidney Stone, Retrograde Intrarenal Surgery (RIRS) | Not applicable | Not yet recruiting | murat sahin | 60 | 2026-06-01 | 2026-06-09 |
| Prospective Multi-center Study Comparing Pulsed Tm:YAG Laser to Pulse Modulated Holmium Laser in the Treatment of Nephrolithiasis With FANS Access Sheaths Moses Holmium:YAG laser, Thulium:YAG laser - Kidney Stone | Not applicable | Not yet recruiting | NYU Langone Health | 70 | 2026-06-01 | 2026-04-07 |
| Evaluation of Renal Injury After RIRS Using Shear-Wave Elastography Aspiration-assisted ureteral access sheath, Standard ureteral access sheath - Kidney Stone | Not applicable | Not yet recruiting | Cengiz Canakci, MD | 60 | 2026-06-01 | 2026-06-03 |
| Safety and Efficacy of Combination of Tamsulosin 0.4 mg Plus Tadalafil 5mg Versus 2.5 mg Tamsulosin - Kidney Stone, Ureteric Stone | Not applicable | Recruiting | Ain Shams University | 140 | 2025-12-01 | 2026-05-01 |
| Oxalate and Citrate in Humans - Response to Citrate Kidney stone formers, Control cohort - Kidney Stone, Healthy | Not applicable | Recruiting | University of Chicago | 24 | 2025-10-01 | 2025-12-16 |
| Access Sheath and Stent Trial Surveys - Kidney Stone, Ureteral Stone | Not applicable | Recruiting | University of Michigan | 184 | 2025-09-24 | 2025-12-22 |
| Utilization of a Web-Based Application to Improve Patient Health Literacy and Reduce Clinic Visit Times in Holmium Laser Enucleation of the Prostate (HoLEP) Procedures and Kidney Stone Surgery WellPrept, Standard Care - Kidney Stone, Benign Prostatic Hyperplasia | Not applicable | Active not recruiting | Northwestern University | 300 | 2025-09-17 | 2026-11-09 |
| HoYAG vs TFL in miniPCNL With ClearPetra HoYAG laser, TFL laser platform - Nephrolithiasis, Kidney Stone | Not applicable | Recruiting | University of Kansas Medical Center | 150 | 2025-08-22 | 2026-05-06 |
| A Novel Ureteric Stent in Kidney Stone Patients and Oncology Patients Compared to a Conventional JJ Stent Experimental ureteric stent with specially shaped side-holes that prevent stagnation points (i.e., areas of low flow that cause particles to settle and E&B), Qualitative interview - Catheter Blockage, Oncology | Not applicable | Recruiting | University of Southampton | 50 | 2025-08-06 | 2026-05-11 |
| A Single-Center Clinical Study on the Efficacy and Safety of VISOR Multifunctional Integrated Flexible Ureteroscope - Urolithiasis, Calcium Oxalate, Kidney Stone | Not applicable | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 20 | 2025-08-06 | 2025-09-26 |
| Research on Early Warning and Diagnosis & Treatment Pathway for Micro Kidney Stones Detect the levels of metabolites in blood and urine - Kidney Stone | Completed | Xijing Hospital | 20 | 2025-08-01 | 2026-03-12 | |
| ClearPetra™ Vacuum-assisted Ureteral Access Sheath vs Traditional Approach ClearPetra Ureteral access sheath - Nephrolithiasis, Kidney Stone | Not applicable | Terminated | University of Kansas Medical Center | 3 | 2025-07-31 | 2026-05-06 |
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Kidney Calculi (146) · Nephrolithiasis (27) · Urolithiasis (23) · Ureterolithiasis (10) · Kidney Diseases (6) · Nephrolithiasis, Calcium Oxalate (5) · Pain, Postoperative (5) · Emergencies (4) · Renal Colic (4) · Ureteral Calculi (4) · Urinary Calculi (4) · Hyperoxaluria (3) · Infections (3) · Pain (2) · Recurrence (2)
Calculi (146) · Female Urogenital Diseases (146) · Female Urogenital Diseases and Pregnancy Complications (146) · Male Urogenital Diseases (146) · Pathological Conditions, Anatomical (146) · Pathological Conditions, Signs and Symptoms (146) · Urogenital Diseases (145) · Urologic Diseases (144) · Urinary Calculi (142) · Kidney Diseases (140) · Urolithiasis (123) · Nephrolithiasis (119) · Pathologic Processes (16) · Ureteral Diseases (15) · Signs and Symptoms (10)
Nephrolithotomy, Percutaneous (4) · Blood Specimen Collection (3) · Potassium Citrate (3) · Dust (2) · Furosemide (2) · Isoproterenol (2) · Ketorolac Tromethamine (2) · Lithotripsy (2) · Ropivacaine (2) · Sodium Bicarbonate (2) · Standard of Care (2) · Ureteroscopy (2) · empagliflozin (2) · Analgesics, Non-Narcotic (1) · Analgesics, Opioid (1)
University of Alabama at Birmingham (12) · The First Affiliated Hospital of Guangzhou Medical University (5) · University of Chicago (5) · Centre hospitalier de l'Université de Montréal (CHUM) (4) · Northwestern University (4) · Region Skane (4) · University of Kansas Medical Center (4) · Ankara Training and Research Hospital (3) · Assiut University (3) · Calyxo, Inc. (3) · Children's Hospital of Philadelphia (3) · Insel Gruppe AG, University Hospital Bern (3) · The Cleveland Clinic (3) · University of Michigan (3) · Agnieszka Pozdzik (2)
United States (63) · Canada (13) · China (12) · Egypt (12) · Turkey (Türkiye) (7) · France (5) · Sweden (4) · Switzerland (4) · Belgium (3) · Denmark (3) · Russia (3) · Italy (2) · Finland (1) · Germany (1) · India (1)
Dean Assimos, MD (3) · Sonia Fargue, PhD (3) · Tanecia Mitchell, PhD (3) · Ali Kaan Yildiz (2) · Amy Krambeck, MD (2) · Hazem Elmansy, MD (2) · Jorge Gutierrez-Aceves, MD (2) · Magnus Wagenius, PhD (2) · Manoj Monga, MD (2) · Naeem Bhojani, MD (2) · Wilson Molina, MD (2) · Abdul Latif Mohammed Zayed, professor of urology (1) · Abul-fotouh Ahmed (1) · Alana Desai, MD (1)
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P20DK119788 (2), R01DK137784 (2), 2005 (1), 2015 (1), 2023 (1), K23DK127252 (1), R01DK124469 (1), R01DK126774 (1), R01DK128160 (1), R03DK123542 (1)